Research Output 2006 2019

2019

A pilot study in PROMETHEUS: MRI Proton density fat fraction is feasible in morbidly obese patients and results equivalent to liver biopsy

Wernberg, C., 1. Jul 2019.

Research output: Contribution to conference without publisher/journalPosterResearch

Combination of CCL4 with alcoholic and metabolic injuries mimics human liver fibrosis

Galaxy Consortium, 1. Aug 2019, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 317, 2, p. G182-G194

Research output: Contribution to journalJournal articleResearchpeer-review

Liver Cirrhosis
Wounds and Injuries
Ethanol
Alcoholic Fatty Liver
Pharmaceutical Preparations

Cost-effectiveness of non-invasive screening for alcohol-related liver fibrosis

Galaxy Consortium, 8. Oct 2019, In : Hepatology (Baltimore, Md.).

Research output: Contribution to journalJournal articleResearchpeer-review

Liver Cirrhosis
Cost-Benefit Analysis
Quality-Adjusted Life Years
Alcohols
Liver

Extracellular Matrix Fragments of the Basement Membrane and the Interstitial Matrix Are Serological Markers of Intestinal Tissue Remodeling and Disease Activity in Dextran Sulfate Sodium Colitis

Lindholm, M., Manon-Jensen, T., Madsen, G. I., Krag, A., Karsdal, M. A., Kjeldsen, J. & Mortensen, J. H., 24. May 2019, In : Digestive Diseases and Sciences.

Research output: Contribution to journalJournal articleResearchpeer-review

Dextran Sulfate
Colitis
Extracellular Matrix Proteins
Collagen Type III
Matrix Metalloproteinases

Lever- og galdevejssygdomme

Ott, P., Bendtsen, F., Grønbæk, H., Krag, A. & Larsen, F. S., 2019, Medicinsk Kompendium. de Muckadell, O. B. S., Hastrup Svendsen, J. & Vilstrup, H. (eds.). 19. ed. Munksgaard , Vol. 1. p. 1121-1201

Research output: Chapter in Book/Report/Conference proceedingBook chapterEducation

Liver Fibrosis and Metabolic Alterations in Adults With alpha-1-antitrypsin Deficiency Caused by the Pi*ZZ Mutation

European Alpha1-Liver Study Group, 1. Sep 2019, In : Gastroenterology. 157, 3, p. 705-719.e18

Research output: Contribution to journalJournal articleResearchpeer-review

alpha 1-Antitrypsin Deficiency
Liver Cirrhosis
Mutation
Liver
Liver Diseases

Serological Assessment of the Quality of Wound Healing Processes in Crohn's Disease

Sun, S., Karsdal, M. A., Mortensen, J. H., Luo, Y., Kjeldsen, J., Krag, A., Jensen, M. D., Bay-Jensen, A. C. & Manon-Jensen, T., 1. Jun 2019, In : Journal of gastrointestinal and liver diseases : JGLD. 28, 2, p. 175-182

Research output: Contribution to journalJournal articleResearchpeer-review

Crohn Disease
Area Under Curve
Intestines
Peptides
Serum

Spleen stiffness to liver stiffness ratio significantly differs between ALD and HCV and predicts disease-specific complications

Elshaarawy, O., Mueller, J., Guha, I. N., Chalmers, J., Harris, R., Krag, A., Stæhr Madsen, B., Stefanescu, H., Farcau, O., Ardelean, A., Procopet, B., Thiele, M. & Mueller, S., Aug 2019, In : JHEP Reports. 1, 2, p. 99-106

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File

Statiner er sikre ved leversygdom og har muligvis en gunstig effekt

Translated title of the contribution: Statins are safe in patients with liver diseases and may have a beneficial effectBalle Hugger, M., Bastrup Israelsen, M., Dalby Hansen, C. & Krag, A., 8. Jul 2019, In : Ugeskrift for Laeger. 181, V11180794.

Research output: Contribution to journalJournal articleResearchpeer-review

Hydroxymethylglutaryl-CoA Reductase Inhibitors
Liver Diseases
Liver
Wounds and Injuries
Enzymes

Time to Reconsider Listing Criteria for Alcohol-Associated Liver Disease?

Louvet, A. & Krag, A., Sep 2019, In : Liver Transplantation. 25, 9, p. 1303-1304

Research output: Contribution to journalEditorialResearchpeer-review

Trænger din lever til en måned uden fedt og alkohol?

Lindvig, K. P. & Thiele, M., 12. Jan 2019, In : Videnskab.dk.

Research output: Contribution to journalJournal articleCommunication

Transient elastography for screening of liver fibrosis: cost-effectiveness analysis from six prospective cohorts in Europe and Asia

investigators of the LiverScreen Consortium, 27. Aug 2019, In : Journal of Hepatology.

Research output: Contribution to journalJournal articleResearchpeer-review

Liver Cirrhosis
Cost-Benefit Analysis
Quality-Adjusted Life Years
Liver
Delivery of Health Care
2018
59 Downloads (Pure)

Accuracy of the Enhanced Liver Fibrosis Test vs Fibrotest, Elastography and Indirect Markers in Detection of Advanced Fibrosis in Patients with Alcoholic Liver Disease

Thiele, M., Madsen, B. S., Hansen, J. F., Detlefsen, S., Antonsen, S. & Krag, A., Apr 2018, In : Gastroenterology. 154, 5, p. 1369-1379

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Liver Cirrhosis
ROC Curve
Primary Health Care
Secondary Care Centers
Alcohols
99 Downloads (Pure)

Acute decompensation boosts hepatic collagen type III deposition and deteriorates experimental and human cirrhosis

Praktiknjo, M., Lehmann, J., Nielsen, M. J., Schierwagen, R., Uschner, F. E., Meyer, C., Thomas, D., Strassburg, C. P., Bendtsen, F., Møller, S., Krag, A., Karsdal, M. A., Leeming, D. J. & Trebicka, J., 2018, In : Hepatology communications. 2, 2, p. 211-222

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Collagen Type III
Liver Cirrhosis
Liver
Transjugular Intrahepatic Portasystemic Shunt
Ligation
107 Downloads (Pure)

Antifibrotic and molecular aspects of rifaximin in alcoholic liver disease: Study protocol for a randomized controlled trial

Madsen, B. S., Trebicka, J., Thiele, M., Israelsen, M., Arumugan, M., Havelund, T. & Krag, A., 26. Feb 2018, In : Trials. 19, 5 p., 143.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Liver Cirrhosis
Randomized Controlled Trials
Microbiota
Liver Diseases
Placebos
89 Downloads (Pure)

Assessment of biopsy-proven liver fibrosis by two-dimensional shear wave elastography: An individual patient data based meta-analysis

Herrmann, E., de Lédinghen, V., Cassinotto, C., Chu, W. C-W., Leung, V. Y-F., Ferraioli, G., Filice, C., Castera, L., Vilgrain, V., Ronot, M., Dumortier, J., Guibal, A., Pol, S., Trebicka, J., Jansen, C., Strassburg, C. P., Zheng, R., Zheng, J., Francque, S., Vanwolleghem, T. & 11 others, Vonghia, L., Manesis, E. K., Zoumpoulis, P., Sporea, I., Thiele, M., Krag, A., Cohen-Bacrie, C., Criton, A., Gay, J., Deffieux, T. & Friedrich-Rust, M., Jan 2018, In : Hepatology. 67, 1, p. 260–272

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Liver Cirrhosis
Meta-Analysis
Hepatitis B
ROC Curve
Chronic Hepatitis C
78 Downloads (Pure)

Association Between Portosystemic Shunts and Increased Complications and Mortality in Patients With Cirrhosis

Simón-Talero, M., Roccarina, D., Martínez, J., Lampichler, K., Baiges, A., Low, G., Llop, E., Praktiknjo, M., Maurer, M. H., Zipprich, A., Triolo, M., Vangrinsven, G., Garcia-Martinez, R., Dam, A., Majumdar, A., Picón, C., Toth, D., Darnell, A., Abraldes, J. G., Lopez, M. & 31 others, Kukuk, G., Krag, A., Bañares, R., Laleman, W., La Mura, V., Ripoll, C., Berzigotti, A., Trebicka, J., Calleja, J. L., Tandon, P., Hernandez-Gea, V., Reiberger, T., Albillos, A., Tsochatzis, E. A., Augustin, S., Genescà, J., Quiroga, S., Yu, D., Mandorfer, M., Garcia-Pagan, J. C., Berbel, C., Ferrusquia, J., Ble, M., Garcia-Criado, M. A., Belmonte, E., Ney, M., Margini, C., Casu, S., Murgia, G., Ludwig, C. & Baveno VI-SPSS group from the Baveno Cooperation, Baveno VI-SPSS group, May 2018, In : Gastroenterology. 154, 6, p. 1694-1705.e4

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Hepatic Encephalopathy
Liver Diseases
Liver
Confidence Intervals
Viscera
95 Downloads (Pure)

Controlled Attenuation Parameter And Alcoholic Hepatic Steatosis: Diagnostic Accuracy and Role Of Alcohol Detoxification

Thiele, M., Rausch, V., Fluhr, G., Kjærgaard, M., Piecha, F., Mueller, J., Straub, B. K., Lupşor-Platon, M., De-Ledinghen, V., Seitz, H. K., Detlefsen, S., Madsen, B., Krag, A. & Mueller, S., May 2018, In : Journal of Hepatology. 68, 5, p. 1025-1032

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Alcohols
Liver
Area Under Curve
Fats
Fatty Liver

EASL Clinical Practice Guidelines for the management of patients with decompensated cirrhosis

Krag, A. & European Association for the Study of the Liver, Aug 2018, In : Journal of Hepatology. 69, 2, p. 406-460

Research output: Contribution to journalJournal articleCommunication

Managing excessive alcohol consumption at a population level: The earlier the better

Louvet, A. & Krag, A., 1. Mar 2018, In : Journal of Hepatology. 68, 3, p. 389-390

Research output: Contribution to journalEditorialResearchpeer-review

57 Downloads (Pure)

Rifaximin has minor effects on bacterial composition, inflammation and bacterial translocation in cirrhosis: A randomized trial

Kimer, N., Pedersen, J. S., Tavenier, J., Christensen, J. E., Busk, T. M., Hobolth, L., Krag, A., Al-Soud, W. A., Mortensen, M. S., Sørensen, S. J., Møller, S., Bendtsen, F. & And members of the CoRif study group, Jan 2018, In : Journal of Gastroenterology and Hepatology. 33, 1, p. 307–314

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Bacterial Translocation
rRNA Genes
Feces
Placebos
Bacterial DNA

Sådan påvirker decembers flæsk, sovs og snaps din fordøjelse

Thiele, M., 9. Dec 2018, In : Videnskab.dk.

Research output: Contribution to journalContribution to newspaper - Newspaper articleCommunication

2017

Contemporary use of elastography in liver fibrosis and portal hypertension

Thiele, M., Kjærgaard, M., Thielsen, P. & Krag, A., 2017, In : Clinical Physiology and Functional Imaging. 37, 3, p. 235–242

Research output: Contribution to journalReviewResearchpeer-review

Portal Hypertension
Liver Cirrhosis
Liver Diseases
Liver
Precision Medicine
93 Downloads (Pure)

High risk of misinterpreting liver and spleen stiffness using 2D shear-wave and transient elastography after a moderate or high calorie meal

Kjærgaard, M., Thiele, M., Jansen, C., Stæhr Madsen, B., Görtzen, J., Strassburg, C. P., Trebicka, J. & Krag, A., 2017, In : PLOS ONE. 12, 4, 15 p., e0173992.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Shear waves
Liver
shears
Meals
spleen
144 Downloads (Pure)

Pharmacological interventions for alcoholic liver disease (alcohol-related liver disease): an attempted network meta-analysis

Buzzetti, E., Kalafateli, M., Thorburn, D., Davidson, B. R., Thiele, M., Gluud, L. L., Del Giovane, C., Askgaard, G., Krag, A., Tsochatzis, E. & Gurusamy, K. S., 2017, In : Cochrane Database of Systematic Reviews. 2017, 3, 182 p., CD011646.

Research output: Contribution to journalReviewResearchpeer-review

Open Access
File
Alcoholic Hepatitis
Liver Diseases
Alcohols
Randomized Controlled Trials
Propylthiouracil

Prediction of presence of oesophageal varices just by shear-wave elastography of the liver and spleen

Jansen, C., Thiele, M., Verlinden, W., Krag, A., Francque, S. & Trebicka, J., 2017, In : Liver International. 37, 9, p. 1406-1407

Research output: Contribution to journalComment/debateResearch

116 Downloads (Pure)

Quality of life and pituitary function in patients with hereditary hemochromatosis: An observational study

Dahl, E., Haaber, A., Kimer, N., Thiele, M., Bach, J. & Gluud, L. L., 2017, In : Journal of Gastroenterology and Hepatology Research. 2, 1, 6 p., 006.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
67 Downloads (Pure)

Terlipressin versus other vasoactive drugs for hepatorenal syndrome

Israelsen, M., Krag, A., Allegretti, A. S., Jovani, M., Goldin, A. H., Winter, R. W. & Gluud, L. L., 2017, In : Cochrane Database of Systematic Reviews. 9, 62 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Hepatorenal Syndrome
Odds Ratio
Pharmaceutical Preparations
Confidence Intervals
Octreotide
2012

Meta-analysis: Banding ligation and medical interventions for the prevention of rebleeding from oesophageal varices

Thiele, M., Krag, A., Rohde, U. & Gluud, L. L., 1. May 2012, In : Alimentary Pharmacology and Therapeutics. 35, 10, p. 1155-1165 11 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
Esophageal and Gastric Varices
Ligation
Meta-Analysis
Numbers Needed To Treat
Regression Analysis
2011

Common variable immunodeficiency diagnosed by capsule endoscopy.

Theede, K., Thiele, M. & Langholz, E., 2011, In : Endoskopie.

Research output: Contribution to journalJournal articleResearchpeer-review

2009

Higher intramuscular triacylglycerol in women does not impair insulin sensitivity and proximal insulin signaling

Høeg, L., Roepstorff, C., Thiele, M., Richter, E. A., Wojtaszewski, J. F. P. & Kiens, B., 1. Sep 2009, In : Journal of Applied Physiology. 107, 3, p. 824-831 8 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Insulin Resistance
Insulin
Slow-Twitch Muscle Fibers
Leg
Follicular Phase
2006

Higher skeletal muscle α2AMPK activation and lower energy charge and fat oxidation in men than in women during submaximal exercise

Roepstorff, C., Thiele, M., Hillig, T., Pilegaard, H., Richter, E. A., Wojtaszewski, J. F. P. & Kiens, B., 1. Jul 2006, In : Journal of Physiology. 574, 1, p. 125-138 14 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
AMP-Activated Protein Kinases
Skeletal Muscle
Fats
Exercise
Muscles

Sex differences in hormone-sensitive lipase expression, activity, and phosphorylation in skeletal muscle at rest and during exercise

Roepstorff, C., Donsmark, M., Thiele, M., Vistisen, B., Stewart, G., Vissing, K., Schjerling, P., Hardie, D. G., Galbo, H. & Kiens, B., 24. Nov 2006, In : American Journal of Physiology - Endocrinology and Metabolism. 291, 5

Research output: Contribution to journalJournal articleResearchpeer-review

Sterol Esterase
Sex Characteristics
Skeletal Muscle
Exercise
Muscles