Supramolecular Receptor Design - Molecular Recognition of Electron Deficient Guests

Kent Nielsen (Lecturer)

Activity: Talks and presentationsTalks and presentations in private or public companies

Description

 

 

Self-assembled structures are wide spread in Nature and are a key feature of many biological small molecule recognition motifs.  Not surprisingly, therefore, considerable effort has been devoted to developing synthetic self-assembled receptor systems, multi-component molecular hosts, that are able to interact with and binding specifically targeted substrates. In this context, the tetraTTF-calix[4]pyrrole (Fig. 1), acts as a multi-faceted receptor in that it interacts with an assortment of different guests in different ways. It will be demonstrated that: a) tetra(TTF)-calix[4]pyrrole function as an excellent chemosensor capable of detecting explosives - such as trinitrotoluene (TNT) - commonly used in landmines through a simple color change from yellow to green; b) that the conformation of the receptor can be reversibly switched between the 1,3-alternate conformation and the cone conformation by the repetitive addition of chloride and sodium ions, and finally; c) that the receptor is capable of encapsulate C60 and, in doing so, produce an easy-to-visualize color change.
Period30. Sep 2009
Event title  Supramolecular Receptor Design - Molecular Recognition of Electron Deficient Guests: null
Event typeConference
LocationSuwon, Korea, Republic of