Activity: Talks and presentations › Talks and presentations in private or public companies
Self-assembled structures are wide spread in Nature and are a key feature of many biological small molecule recognition motifs. Not surprisingly, therefore, considerable effort has been devoted to developing synthetic self-assembled receptor systems, multi-component molecular hosts, that are able to interact with and binding specifically targeted substrates. In this context, the tetraTTF-calixpyrrole (Fig. 1), acts as a multi-faceted receptor in that it interacts with an assortment of different guests in different ways. It will be demonstrated that: a) tetra(TTF)-calixpyrrole function as an excellent chemosensor capable of detecting explosives - such as trinitrotoluene (TNT) - commonly used in landmines through a simple color change from yellow to green; b) that the conformation of the receptor can be reversibly switched between the 1,3-alternate conformation and the cone conformation by the repetitive addition of chloride and sodium ions, and finally; c) that the receptor is capable of encapsulate C60 and, in doing so, produce an easy-to-visualize color change.
30. Sep 2009
Supramolecular Receptor Design - Molecular Recognition of Electron Deficient Guests: null