What is the cause of death, when alcohol dependent persons die prematurely?

Ali Mohamad Abdul Ghani, Edris Faiz, Anette Søgaard Nielsen, Randi Marie Bilberg

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Resumé

Background
Although individuals with alcohol use disorder (AUD) have a significantly shorter lifespan than the general population, there is sparse evidence on cause of death when alcohol dependent people die prematurely. Especially the somatic causes of death are shed less light on.

Aim
To determine the cause of premature death in individuals with AUD based on recent studies.

Methods
This systematic review summarizes evidence from the last 10 years with cohort studies consisting of AUD patients with the subsequent outcome of cause of death and with at least two years of follow-up.

Results
Nine studies were included of which only two were assessed to be of good quality. Furthermore, two studies were of moderately good and acceptable quality, respectively. This review found increased mortality in AUD individuals with the main causes of death being malignancy, and problems of the cardiovascular- and the digestive system.

Conclusion
Malignancy was the most common cause of death in the included AUD cohorts, but the overall quality of the included studies in this review is low. There is a need for high-quality studies to better understand cause-specific mortality among AUD individuals.
OriginalsprogEngelsk
TidsskriftDrug and Alcohol Dependence
Vol/bind197
Sider (fra-til)120-126
ISSN0376-8716
DOI
StatusUdgivet - 1. apr. 2019

Fingeraftryk

Cause of Death
Alcohols
Digestive system
Digestive System
Premature Mortality
Cohort Studies
Population
Neoplasms

Citer dette

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title = "What is the cause of death, when alcohol dependent persons die prematurely?",
abstract = "BackgroundAlthough individuals with alcohol use disorder (AUD) have a significantly shorter lifespan than the general population, there is sparse evidence on cause of death when alcohol dependent people die prematurely. Especially the somatic causes of death are shed less light on.AimTo determine the cause of premature death in individuals with AUD based on recent studies.MethodsThis systematic review summarizes evidence from the last 10 years with cohort studies consisting of AUD patients with the subsequent outcome of cause of death and with at least two years of follow-up.ResultsNine studies were included of which only two were assessed to be of good quality. Furthermore, two studies were of moderately good and acceptable quality, respectively. This review found increased mortality in AUD individuals with the main causes of death being malignancy, and problems of the cardiovascular- and the digestive system.ConclusionMalignancy was the most common cause of death in the included AUD cohorts, but the overall quality of the included studies in this review is low. There is a need for high-quality studies to better understand cause-specific mortality among AUD individuals.",
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What is the cause of death, when alcohol dependent persons die prematurely? / Ghani, Ali Mohamad Abdul; Faiz, Edris; Nielsen, Anette Søgaard; Bilberg, Randi Marie.

I: Drug and Alcohol Dependence, Bind 197, 01.04.2019, s. 120-126.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

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T1 - What is the cause of death, when alcohol dependent persons die prematurely?

AU - Ghani, Ali Mohamad Abdul

AU - Faiz, Edris

AU - Nielsen, Anette Søgaard

AU - Bilberg, Randi Marie

PY - 2019/4/1

Y1 - 2019/4/1

N2 - BackgroundAlthough individuals with alcohol use disorder (AUD) have a significantly shorter lifespan than the general population, there is sparse evidence on cause of death when alcohol dependent people die prematurely. Especially the somatic causes of death are shed less light on.AimTo determine the cause of premature death in individuals with AUD based on recent studies.MethodsThis systematic review summarizes evidence from the last 10 years with cohort studies consisting of AUD patients with the subsequent outcome of cause of death and with at least two years of follow-up.ResultsNine studies were included of which only two were assessed to be of good quality. Furthermore, two studies were of moderately good and acceptable quality, respectively. This review found increased mortality in AUD individuals with the main causes of death being malignancy, and problems of the cardiovascular- and the digestive system.ConclusionMalignancy was the most common cause of death in the included AUD cohorts, but the overall quality of the included studies in this review is low. There is a need for high-quality studies to better understand cause-specific mortality among AUD individuals.

AB - BackgroundAlthough individuals with alcohol use disorder (AUD) have a significantly shorter lifespan than the general population, there is sparse evidence on cause of death when alcohol dependent people die prematurely. Especially the somatic causes of death are shed less light on.AimTo determine the cause of premature death in individuals with AUD based on recent studies.MethodsThis systematic review summarizes evidence from the last 10 years with cohort studies consisting of AUD patients with the subsequent outcome of cause of death and with at least two years of follow-up.ResultsNine studies were included of which only two were assessed to be of good quality. Furthermore, two studies were of moderately good and acceptable quality, respectively. This review found increased mortality in AUD individuals with the main causes of death being malignancy, and problems of the cardiovascular- and the digestive system.ConclusionMalignancy was the most common cause of death in the included AUD cohorts, but the overall quality of the included studies in this review is low. There is a need for high-quality studies to better understand cause-specific mortality among AUD individuals.

KW - Alcohol dependence

KW - Alcohol use disorders

KW - Cause of death

KW - Malignancy

KW - Mortality

KW - Somatic

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DO - 10.1016/j.drugalcdep.2018.11.032

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JO - Drug and Alcohol Dependence

JF - Drug and Alcohol Dependence

SN - 0376-8716

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