Resumé
Although individuals with alcohol use disorder (AUD) have a significantly shorter lifespan than the general population, there is sparse evidence on cause of death when alcohol dependent people die prematurely. Especially the somatic causes of death are shed less light on.
Aim
To determine the cause of premature death in individuals with AUD based on recent studies.
Methods
This systematic review summarizes evidence from the last 10 years with cohort studies consisting of AUD patients with the subsequent outcome of cause of death and with at least two years of follow-up.
Results
Nine studies were included of which only two were assessed to be of good quality. Furthermore, two studies were of moderately good and acceptable quality, respectively. This review found increased mortality in AUD individuals with the main causes of death being malignancy, and problems of the cardiovascular- and the digestive system.
Conclusion
Malignancy was the most common cause of death in the included AUD cohorts, but the overall quality of the included studies in this review is low. There is a need for high-quality studies to better understand cause-specific mortality among AUD individuals.
| Originalsprog | Engelsk |
|---|---|
| Tidsskrift | Drug and Alcohol Dependence |
| Vol/bind | 197 |
| Sider (fra-til) | 120-126 |
| ISSN | 0376-8716 |
| DOI | |
| Status | Udgivet - 1. apr. 2019 |
Fingeraftryk
Citer dette
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What is the cause of death, when alcohol dependent persons die prematurely? / Ghani, Ali Mohamad Abdul; Faiz, Edris; Nielsen, Anette Søgaard; Bilberg, Randi Marie.
I: Drug and Alcohol Dependence, Bind 197, 01.04.2019, s. 120-126.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
TY - JOUR
T1 - What is the cause of death, when alcohol dependent persons die prematurely?
AU - Ghani, Ali Mohamad Abdul
AU - Faiz, Edris
AU - Nielsen, Anette Søgaard
AU - Bilberg, Randi Marie
PY - 2019/4/1
Y1 - 2019/4/1
N2 - BackgroundAlthough individuals with alcohol use disorder (AUD) have a significantly shorter lifespan than the general population, there is sparse evidence on cause of death when alcohol dependent people die prematurely. Especially the somatic causes of death are shed less light on.AimTo determine the cause of premature death in individuals with AUD based on recent studies.MethodsThis systematic review summarizes evidence from the last 10 years with cohort studies consisting of AUD patients with the subsequent outcome of cause of death and with at least two years of follow-up.ResultsNine studies were included of which only two were assessed to be of good quality. Furthermore, two studies were of moderately good and acceptable quality, respectively. This review found increased mortality in AUD individuals with the main causes of death being malignancy, and problems of the cardiovascular- and the digestive system.ConclusionMalignancy was the most common cause of death in the included AUD cohorts, but the overall quality of the included studies in this review is low. There is a need for high-quality studies to better understand cause-specific mortality among AUD individuals.
AB - BackgroundAlthough individuals with alcohol use disorder (AUD) have a significantly shorter lifespan than the general population, there is sparse evidence on cause of death when alcohol dependent people die prematurely. Especially the somatic causes of death are shed less light on.AimTo determine the cause of premature death in individuals with AUD based on recent studies.MethodsThis systematic review summarizes evidence from the last 10 years with cohort studies consisting of AUD patients with the subsequent outcome of cause of death and with at least two years of follow-up.ResultsNine studies were included of which only two were assessed to be of good quality. Furthermore, two studies were of moderately good and acceptable quality, respectively. This review found increased mortality in AUD individuals with the main causes of death being malignancy, and problems of the cardiovascular- and the digestive system.ConclusionMalignancy was the most common cause of death in the included AUD cohorts, but the overall quality of the included studies in this review is low. There is a need for high-quality studies to better understand cause-specific mortality among AUD individuals.
KW - Alcohol dependence
KW - Alcohol use disorders
KW - Cause of death
KW - Malignancy
KW - Mortality
KW - Somatic
U2 - 10.1016/j.drugalcdep.2018.11.032
DO - 10.1016/j.drugalcdep.2018.11.032
M3 - Journal article
VL - 197
SP - 120
EP - 126
JO - Drug and Alcohol Dependence
JF - Drug and Alcohol Dependence
SN - 0376-8716
ER -