Vitamin D status and health-related quality of life in patients with Type 2 diabetes

Y H M Krul-Poel, S Westra, H J van Wijland, F Stam, Paul Lips, F Pouwer, S Simsek

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Abstrakt

AIMS: To test whether vitamin D status was associated with health-related quality of life in people with Type 2 diabetes mellitus.

METHODS: Demographic and clinical characteristics, including health-related quality of life scores, were obtained from 241 adult patients with Type 2 diabetes managed with oral hypoglycaemic agents. Health-related quality of life was assessed using the Short-Form 36 Health Survey. Multiple logistic regression analysis was used to investigate the association between vitamin D status and health-related quality of life, with adjustment for confounders.

RESULTS: The mean age of the patients included in the study was 67 ± 8 years. Their mean HbA1c concentration was 52 ± 8 mmol/mol (6.9 ± 0.7%) and their mean serum 25-hydroxyvitamin D concentration was 59 ± 23 nmol/l. Vitamin D deficiency (serum 25-hydroxyvitamin D < 50 nmol/l) was present in 38% of patients. No significant associations were found between vitamin D status and health-related quality of life.

CONCLUSIONS: Vitamin D status was not associated with health-related quality of life in patients with Type 2 diabetes. This could be explained by the relatively high serum 25-hydroxyvitamin D concentration, good glycaemic control and relatively good health-related quality of life of all patients. A prospective study among patients with vitamin D deficiency and poor glycaemic control would be interesting for future research.

OriginalsprogEngelsk
TidsskriftDiabetic Medicine
Vol/bind33
Udgave nummer3
Sider (fra-til)300-6
Antal sider7
ISSN0742-3071
DOI
StatusUdgivet - mar. 2016

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