Virtual magnetic resonance elastography predicts the intraoperative consistency of meningiomas

Jan Saip Aunan-Diop*, Mikkel Christian Schou Andersen, Ancuta Ioana Friismose, Bo Halle, Christian Bonde Pedersen, Bo Mussmann, Mads Hjortdal Grønhøj, Troels Halfeld Nielsen, Ulla Jensen, Frantz Rom Poulsen


Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

7 Downloads (Pure)


Background and purpose: Virtual magnetic resonance elastography (vMRE) is an experimental imaging modality designed to non-invasively predict the haptic properties of tissues. The modality is sensitive to tissue stiffness and fibrosis. Information about meningioma consistency prior to resection is of great interest in neurological surgery as the surgical plan and outcome may be affected by the tumor's stiffness. In this study, we assessed the ability of vMRE to predict the intraoperative consistency and mechanical heterogeneity of intracranial meningiomas. Materials and methods: We included 12 patients scheduled for meningioma resection, of which one patient was found to have a solitary fibrous tumor on histological examination. All participants underwent preoperative vMRE and intraoperative consistency grading. Results and Conclusions: Intraoperative qualitative consistency correlated positively with vMRE-based consistency assessment (odds ratio 5.63, 95% CI 1.12–28.30, p = 0.04) at b1000. Mechanically homogenous tumors had significantly lower ∆ mean stiffness than heterogeneous tumors (8.13 vs 18.07 kPa, p = 0.01). This study thus demonstrates a possible clinical application of vMRE in predicting the intraoperative consistency and mechanical heterogeneity of meningiomas.

TidsskriftJournal of Neuroradiology
Udgave nummer4
Sider (fra-til)396-401
StatusUdgivet - jun. 2023

Bibliografisk note

Funding Information:
We wish to thank MD-PhD Claire Gudex - medical writer, for contributing with proofreading and document editing.

Publisher Copyright:
© 2022 The Author(s)


Dyk ned i forskningsemnerne om 'Virtual magnetic resonance elastography predicts the intraoperative consistency of meningiomas'. Sammen danner de et unikt fingeraftryk.