Validating the HeartQoL questionnaire in patients with atrial fibrillation

Marie S Kristensen, Ann-Dorthe Zwisler, Selina K Berg, Graziella Zangger, Charlotte N Grønset, Signe S Risom, Susanne S Pedersen, Neil Oldridge, Lau C Thygesen

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Resumé

BACKGROUND: Atrial fibrillation (AF) is associated with impaired health-related quality-of-life (HRQL). When assessing HRQL, disease-specific and generic instruments are used, which may hinder outcome comparisons across studies. A newly developed core ischaemic heart disease-specific HRQL questionnaire, the HeartQoL, offers a single measurement instrument which may allow outcome comparisons across cardiac diseases. The aim of the study was to evaluate the psychometric properties of HeartQoL in an AF population treated with ablation by assessing its factor structure, construct validity, internal consistency, and test-retest reliability.

DESIGN AND METHODS: Data were collected in two phases: (a) a cross-sectional study including 462 patients with AF/atrial flutter who completed the HeartQoL and the Short-Form 36 (SF-36), allowing for the evaluation of internal consistency, factor structure and construct validity; and (b) a longitudinal study including 55 patients completing HeartQoL twice to evaluate test-retest reliability.

RESULTS: The two-factor structure of HeartQoL was largely confirmed in patients with AF. Internal consistency was high (Cronbach's alpha (α) ≥ 0.90) and test-retest reliability good (intra-class correlation ≥ 0.90). The construct validity was supported, as subscales of HeartQoL correlated strongly with similar (r ≥ 0.78) and weakly (r ≤ 0.47) with dissimilar subscales of SF-36. The HeartQoL demonstrated ability to distinguish between different clinical subgroups of patients, indicating sensitivity.

CONCLUSION: The HeartQoL showed overall satisfactory psychometric properties, demonstrating it to be a valid instrument in the evaluation of HRQL in patients with AF treated with ablation. This suggests that HeartQoL may be a valuable instrument for making HRQL comparisons across the spectrum of cardiac diseases.

OriginalsprogEngelsk
TidsskriftEuropean Journal of Preventive Cardiology
Vol/bind23
Udgave nummer14
Sider (fra-til)1496-1503
ISSN2047-4873
DOI
StatusUdgivet - 14. mar. 2016

Fingeraftryk

Quality of Life
Reproducibility of Results
Psychometrics
Longitudinal Studies
Cross-Sectional Studies
Surveys and Questionnaires
Population

Citer dette

Kristensen, Marie S ; Zwisler, Ann-Dorthe ; Berg, Selina K ; Zangger, Graziella ; Grønset, Charlotte N ; Risom, Signe S ; Pedersen, Susanne S ; Oldridge, Neil ; Thygesen, Lau C. / Validating the HeartQoL questionnaire in patients with atrial fibrillation. I: European Journal of Preventive Cardiology. 2016 ; Bind 23, Nr. 14. s. 1496-1503.
@article{947ee0d31a6a4f7e9fd6e20ee9cbf4b6,
title = "Validating the HeartQoL questionnaire in patients with atrial fibrillation",
abstract = "BACKGROUND: Atrial fibrillation (AF) is associated with impaired health-related quality-of-life (HRQL). When assessing HRQL, disease-specific and generic instruments are used, which may hinder outcome comparisons across studies. A newly developed core ischaemic heart disease-specific HRQL questionnaire, the HeartQoL, offers a single measurement instrument which may allow outcome comparisons across cardiac diseases. The aim of the study was to evaluate the psychometric properties of HeartQoL in an AF population treated with ablation by assessing its factor structure, construct validity, internal consistency, and test-retest reliability.DESIGN AND METHODS: Data were collected in two phases: (a) a cross-sectional study including 462 patients with AF/atrial flutter who completed the HeartQoL and the Short-Form 36 (SF-36), allowing for the evaluation of internal consistency, factor structure and construct validity; and (b) a longitudinal study including 55 patients completing HeartQoL twice to evaluate test-retest reliability.RESULTS: The two-factor structure of HeartQoL was largely confirmed in patients with AF. Internal consistency was high (Cronbach's alpha (α) ≥ 0.90) and test-retest reliability good (intra-class correlation ≥ 0.90). The construct validity was supported, as subscales of HeartQoL correlated strongly with similar (r ≥ 0.78) and weakly (r ≤ 0.47) with dissimilar subscales of SF-36. The HeartQoL demonstrated ability to distinguish between different clinical subgroups of patients, indicating sensitivity.CONCLUSION: The HeartQoL showed overall satisfactory psychometric properties, demonstrating it to be a valid instrument in the evaluation of HRQL in patients with AF treated with ablation. This suggests that HeartQoL may be a valuable instrument for making HRQL comparisons across the spectrum of cardiac diseases.",
author = "Kristensen, {Marie S} and Ann-Dorthe Zwisler and Berg, {Selina K} and Graziella Zangger and Gr{\o}nset, {Charlotte N} and Risom, {Signe S} and Pedersen, {Susanne S} and Neil Oldridge and Thygesen, {Lau C}",
note = "{\circledC} The European Society of Cardiology 2016.",
year = "2016",
month = "3",
day = "14",
doi = "10.1177/2047487316638485",
language = "English",
volume = "23",
pages = "1496--1503",
journal = "European Journal of Preventive Cardiology",
issn = "2047-4873",
publisher = "SAGE Publications",
number = "14",

}

Validating the HeartQoL questionnaire in patients with atrial fibrillation. / Kristensen, Marie S; Zwisler, Ann-Dorthe; Berg, Selina K; Zangger, Graziella; Grønset, Charlotte N; Risom, Signe S; Pedersen, Susanne S; Oldridge, Neil; Thygesen, Lau C.

I: European Journal of Preventive Cardiology, Bind 23, Nr. 14, 14.03.2016, s. 1496-1503.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

TY - JOUR

T1 - Validating the HeartQoL questionnaire in patients with atrial fibrillation

AU - Kristensen, Marie S

AU - Zwisler, Ann-Dorthe

AU - Berg, Selina K

AU - Zangger, Graziella

AU - Grønset, Charlotte N

AU - Risom, Signe S

AU - Pedersen, Susanne S

AU - Oldridge, Neil

AU - Thygesen, Lau C

N1 - © The European Society of Cardiology 2016.

PY - 2016/3/14

Y1 - 2016/3/14

N2 - BACKGROUND: Atrial fibrillation (AF) is associated with impaired health-related quality-of-life (HRQL). When assessing HRQL, disease-specific and generic instruments are used, which may hinder outcome comparisons across studies. A newly developed core ischaemic heart disease-specific HRQL questionnaire, the HeartQoL, offers a single measurement instrument which may allow outcome comparisons across cardiac diseases. The aim of the study was to evaluate the psychometric properties of HeartQoL in an AF population treated with ablation by assessing its factor structure, construct validity, internal consistency, and test-retest reliability.DESIGN AND METHODS: Data were collected in two phases: (a) a cross-sectional study including 462 patients with AF/atrial flutter who completed the HeartQoL and the Short-Form 36 (SF-36), allowing for the evaluation of internal consistency, factor structure and construct validity; and (b) a longitudinal study including 55 patients completing HeartQoL twice to evaluate test-retest reliability.RESULTS: The two-factor structure of HeartQoL was largely confirmed in patients with AF. Internal consistency was high (Cronbach's alpha (α) ≥ 0.90) and test-retest reliability good (intra-class correlation ≥ 0.90). The construct validity was supported, as subscales of HeartQoL correlated strongly with similar (r ≥ 0.78) and weakly (r ≤ 0.47) with dissimilar subscales of SF-36. The HeartQoL demonstrated ability to distinguish between different clinical subgroups of patients, indicating sensitivity.CONCLUSION: The HeartQoL showed overall satisfactory psychometric properties, demonstrating it to be a valid instrument in the evaluation of HRQL in patients with AF treated with ablation. This suggests that HeartQoL may be a valuable instrument for making HRQL comparisons across the spectrum of cardiac diseases.

AB - BACKGROUND: Atrial fibrillation (AF) is associated with impaired health-related quality-of-life (HRQL). When assessing HRQL, disease-specific and generic instruments are used, which may hinder outcome comparisons across studies. A newly developed core ischaemic heart disease-specific HRQL questionnaire, the HeartQoL, offers a single measurement instrument which may allow outcome comparisons across cardiac diseases. The aim of the study was to evaluate the psychometric properties of HeartQoL in an AF population treated with ablation by assessing its factor structure, construct validity, internal consistency, and test-retest reliability.DESIGN AND METHODS: Data were collected in two phases: (a) a cross-sectional study including 462 patients with AF/atrial flutter who completed the HeartQoL and the Short-Form 36 (SF-36), allowing for the evaluation of internal consistency, factor structure and construct validity; and (b) a longitudinal study including 55 patients completing HeartQoL twice to evaluate test-retest reliability.RESULTS: The two-factor structure of HeartQoL was largely confirmed in patients with AF. Internal consistency was high (Cronbach's alpha (α) ≥ 0.90) and test-retest reliability good (intra-class correlation ≥ 0.90). The construct validity was supported, as subscales of HeartQoL correlated strongly with similar (r ≥ 0.78) and weakly (r ≤ 0.47) with dissimilar subscales of SF-36. The HeartQoL demonstrated ability to distinguish between different clinical subgroups of patients, indicating sensitivity.CONCLUSION: The HeartQoL showed overall satisfactory psychometric properties, demonstrating it to be a valid instrument in the evaluation of HRQL in patients with AF treated with ablation. This suggests that HeartQoL may be a valuable instrument for making HRQL comparisons across the spectrum of cardiac diseases.

U2 - 10.1177/2047487316638485

DO - 10.1177/2047487316638485

M3 - Journal article

VL - 23

SP - 1496

EP - 1503

JO - European Journal of Preventive Cardiology

JF - European Journal of Preventive Cardiology

SN - 2047-4873

IS - 14

ER -