Non-specific granulomatous prostatitis (NGP) is histologically defined and reported with an incidence below 3.4% in unselected series of patients. A survey of the literature concerning NGP is given on the basis of a retrospective investigation of 14 case-histories. Microscopically, NGP is characterized by focal or diffuse occurrence of granulomas in the prostate. The etiological significance has been attributed to acute non-specific prostatitis and local hypersensitivity and/or simple foreign-body reactions are considered to be pathogenetic factors. The mean age of patients suffering from NGP is stated to be 54-65 years. Clinically, NGP is poorly defined. Complaints of cystitis/urethritis within the last month and subsequently rapid development or aggravation of urinary obstruction are frequently reported on admission. On digital rectal examination the gland is enlarged, and carcinoma is often suspected. Fine-needle aspiration biopsy may be of some guidance. However, the diagnosis is settled postoperatively by histologic investigation, where prostatic cancer, iatrogenic granulomas and specific granulomatous inflammations must be considered as differential diagnoses. Irrespective the choice of treatment, conservative or surgery, the prognosis of NGP is excellent.
|Tidsskrift||Ugeskrift for Laeger|
|Status||Udgivet - 30. jan. 1989|
- Diagnosis, Differential
- Middle Aged