Use of soluble TREM2 as non-invasive biomarker for NASH

Jonas Heilskov Graversen (Opfinder), Vineesh Indira Chandran (Opfinder), Søren Kragh Moestrup (Opfinder), Maria Kløjgaard Skytthe (Opfinder), Aleksander Krag (Opfinder), Charlotte Wernberg (Opfinder), MM Lauridsen (Opfinder)

Publikation: Patent

Abstract

Reliable non-invasive biomarkers are an unmet clinical need for the diagnosis of NASH patients. Herein we identify soluble TREM2 as a non-invasive plasma biomarker to diagnose NASH in obese patients and provides evidence for sTREM2 as an accurate predictor of advanced hepatic inflammation, ballooning, and fibrosis.
OriginalsprogEngelsk
IPCG01N33/68
PatentnummerWO2022248363 (A1)
Land/OmrådeDanmark
Prioritetsdato28/05/2021
PrioritetsnummerEP20210176575
StatusUdgivet - 1. dec. 2022

Fingeraftryk

Dyk ned i forskningsemnerne om 'Use of soluble TREM2 as non-invasive biomarker for NASH'. Sammen danner de et unikt fingeraftryk.

Citationsformater