TY - PAT
T1 - Use of soluble trem2 as a non-invasive biomarker for non-alcoholic steatohepatitis (NASH)
AU - Graversen, Niels Jonas Heilskov
AU - Chandran, Vineesh Indira
AU - Moestrup, Søren Kragh
AU - Skytthe, Maria Kløjgaard
AU - Krag, Aleksander Ahm
AU - Wernberg, Charlotte
AU - Lauridsen, Mette Enok Munk
PY - 2022/12/1
Y1 - 2022/12/1
N2 - Reliable non-invasive biomarkers are an unmet clinical need for the diagnosis of NASH patients. Herein we identify soluble TREM2 as a non-invasive plasma biomarker to diagnose NASH in obese patients and provides evidence for sTREM2 as an accurate predictor of advanced hepatic inflammation, ballooning, and fibrosis.
AB - Reliable non-invasive biomarkers are an unmet clinical need for the diagnosis of NASH patients. Herein we identify soluble TREM2 as a non-invasive plasma biomarker to diagnose NASH in obese patients and provides evidence for sTREM2 as an accurate predictor of advanced hepatic inflammation, ballooning, and fibrosis.
M3 - Patent
M1 - WO2022248363
ER -