Use of MRI and Biological Therapy in incident patients diagnosed as Ankylosing Spondylitis and Spondyloarthritis: Danish Nationwide Cohort Study 2000-2013

Publikation: Konferencebidrag uden forlag/tidsskriftPosterFormidling


Introduction. Only a few studies have reported incidence of Ankylosing Spondylitis (AS) and Spondyloarthritis (SpA), use of MRI and biological therapy during the last decade.
Aim. To describe the incidence of AS and SpA in the Danish population from 2000-2013 and rates of MRI and biological therapy.

Materials and Methods. All patients with the diagnosis of AS (ICD10:DM45) or SpA (ICD10:DM46) with a valid civil registration in Denmark in the time period from the January1st 2000 until December 31th 2013 were identified in the Danish National Patient Registry. Incident cases were identified and rates of MRI and biological therapy were calculated for each year.

Results. During 2000 until 2013 3620 incident cases were identified (AS: 2116, SpA: 1504). AS are overrepresented by males (58-80%) and SpA by females (58%).
The incident cases of AS increases from 534 (0.52 rate per 100.000) to 828 cases (0.82) from 2005-2009. In 2010-2013 the incidence of AS has decreased to 754 (0.94).
The incident cases of SpA increases from 220 (0.21) in 2009 to 430 (0.43) in 2009 with an additional increase in incidence to 854 (1.06) in 2010-2013.
MRI was used for diagnostic purpose in only 10-15% in 2002. In 2013 the number increased to 95%.
In 2002 biological therapy was prescribed for only a few number of patients followed by an increased number primarily for MB later for SpA, ending at approximately 25% in 2013.

Discussion and conclusion. The incidence of AS stabilizes from 2005 which is in line with previous studies exploring the trends of AS incidence. The incidence of SpA has increased significantly during the time period 2000 to 2013, which is in accordance with introduction of MRI scans for diagnostic use and biological therapy for treatment
Publikationsdato5. okt. 2018
StatusUdgivet - 5. okt. 2018
Begivenhed11th International Congress on Spondyloarthritides - Belgien, Gent, Belgien
Varighed: 4. okt. 20186. okt. 2018


Konference11th International Congress on Spondyloarthritides