Introduction and hypothesis: Our aim was to compare urodynamic findings in urinary incontinent (UI) women with and without diabetes. Methods: In the extensive Lolland-Falster Health Study, women with lower urinary tract symptoms were offered urodynamic testing. After excluding 6 women with incomplete urodynamic testing and 88 women without UI, our analysis ended up including 417 women (31 with and 386 without diabetes). Student’s t-test and chi-squared test were used to compare differences of urodynamic findings. Urodynamic testing consisted of a 2-day bladder diary, post-void residual urine volume, filling cystometry, pressure-flow study, cough stress test, and uroflowmetry. Three experienced physicians in urogynecology evaluated all urodynamic findings leading to an overall conclusion of the test results. Results: Self-reported data showed that compared to incontinent women without diabetes, incontinent women with diabetes had more frequent leakage, a larger amount of leakage, and a higher ICIQ score. A positive ICS Uniform cough stress test was more prevalent in women with diabetes. There were no significant differences in other urodynamic findings or overall conclusion between the two groups. Controlling for age and BMI did not affect our findings. Conclusions: Women with diabetes complained more about UI, had a higher ICIQ score, and had a positive ICS Uniform cough stress test more often than women without diabetes. Based on these findings, we recommend to include the history of urinary incontinence in the care of women with diabetes. This sample consists of women from a comprehensive health study with different severity of UI. Therefore, it can serve as a reference cohort for future studies.
Bibliografisk noteFunding Information:
This study was funded by Nykøbing Falster Hospital; Department of Gynecology and Obstetrics, Nykøbing Falster Hospital; Region Zealand Health Research Fund; Department of Gynecology and Obstetrics, Zealand University Hospital, Roskilde; Production, Research and Innovation, Region Zealand; "Cutting the Edge” prize from Astellas to co-supervisor Lea Laird Andersen; Edith and Henrik Henriksens Memorial Fund; King Christian X's memorial Fund; Grosserer L.F. Foghts Fund; Aase and Ejnar Danielsen Fund; AP Møller Fund.
© 2021, The International Urogynecological Association.