Unlocked nucleic acid (UNA) and UNA derivatives: thermal denaturation studies

Troels Bundgaard Jensen; Niels  Langkjær; Jesper Wengel

doi:10.1093/nass/nrn068

Unlocked nucleic acid (UNA) and UNA derivatives: thermal denaturation studies

Troels Bundgaard Jensen, Niels Langkjær, Jesper Wengel

Publikation: Bidrag til tidsskrift › Konferenceartikel › Forskning › peer review

Abstrakt

A study on the thermal stability of duplexes formed between unlocked nucleic acid (UNA) modified DNA and RNA oligonucleotides and complementary DNA and RNA is presented. The acyclic UNA monomers are shown to induce a decrease in duplex thermal stability.

Originalsprog	Engelsk
Bogserie	Nucleic Acids Symposium Series
Vol/bind	52
Udgave nummer	1
Sider (fra-til)	133-134
ISSN	0261-3166
DOI	https://doi.org/10.1093/nass/nrn068
Status	Udgivet - 2008
Begivenhed	Unlocked nucleic acid (UNA) and UNA derivatives - Varighed: 24. aug. 2010 → …

Konference

Konference	Unlocked nucleic acid (UNA) and UNA derivatives
Periode	24/08/2010 → …

Bibliografisk note

Volumne: 52

Dokumenter og links

10.1093/nass/nrn068

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Citationsformater

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title = "Unlocked nucleic acid (UNA) and UNA derivatives: thermal denaturation studies",

abstract = "A study on the thermal stability of duplexes formed between unlocked nucleic acid (UNA) modified DNA and RNA oligonucleotides and complementary DNA and RNA is presented. The acyclic UNA monomers are shown to induce a decrease in duplex thermal stability.",

author = "Jensen, {Troels Bundgaard} and Niels Langkj{\ae}r and Jesper Wengel",

note = "Volumne: 52; <strong>Unlocked nucleic acid (UNA) and UNA derivatives</strong> ; Conference date: 24-08-2010",

year = "2008",

doi = "10.1093/nass/nrn068",

language = "English",

volume = "52",

pages = "133--134",

journal = "Nucleic Acids Symposium Series",

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T2 - <strong>Unlocked nucleic acid (UNA) and UNA derivatives</strong>

AU - Jensen, Troels Bundgaard

AU - Langkjær, Niels

AU - Wengel, Jesper

N1 - Volumne: 52

PY - 2008

Y1 - 2008

N2 - A study on the thermal stability of duplexes formed between unlocked nucleic acid (UNA) modified DNA and RNA oligonucleotides and complementary DNA and RNA is presented. The acyclic UNA monomers are shown to induce a decrease in duplex thermal stability.

AB - A study on the thermal stability of duplexes formed between unlocked nucleic acid (UNA) modified DNA and RNA oligonucleotides and complementary DNA and RNA is presented. The acyclic UNA monomers are shown to induce a decrease in duplex thermal stability.

U2 - 10.1093/nass/nrn068

DO - 10.1093/nass/nrn068

M3 - Conference article

VL - 52

SP - 133

EP - 134

JO - Nucleic Acids Symposium Series

JF - Nucleic Acids Symposium Series

SN - 0261-3166

IS - 1

Y2 - 24 August 2010

ER -