# Tutorial: using confidence curves in medical research

Ralf Bender, Gabriele Berg, Hajo Zeeb

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

### Resumé

Confidence intervals represent a routinely used standard method to document the uncertainty of estimated effects. In most cases, for the calculation of confidence intervals the conventional fixed 95% confidence level is used. Confidence curves represent a graphical illustration of confidence intervals for confidence levels varying between 0 and 100%. Although such graphs have been repeatedly proposed under different names during the last 40 years, confidence curves are rarely used in medical research. In this paper, we introduce confidence curves and present a short historical review. We draw attention to the different interpretation of one- and two-sided statistical inference. It is shown that these two options also have influence on the plotting of appropriate confidence curves. We illustrate the use of one- and two-sided confidence curves and explain their correct interpretation. In medical research more emphasis on the choice between the one- and two-sided approaches should be given. One- and two-sided confidence curves are useful complements to the conventional methods of presenting study results.

Originalsprog Engelsk Biometrical Journal 47 2 237-47 11 0323-3847 Udgivet - apr. 2005

### Fingeraftryk

Confidence
Curve
Confidence interval
Confidence Level
Statistical Inference
Tutorial
Medical research
Complement
Uncertainty
Graph in graph theory
Interpretation

### Citer dette

Bender, Ralf ; Berg, Gabriele ; Zeeb, Hajo. / Tutorial : using confidence curves in medical research. I: Biometrical Journal. 2005 ; Bind 47, Nr. 2. s. 237-47.
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Bender, R, Berg, G & Zeeb, H 2005, 'Tutorial: using confidence curves in medical research', Biometrical Journal, bind 47, nr. 2, s. 237-47.

Tutorial : using confidence curves in medical research. / Bender, Ralf; Berg, Gabriele; Zeeb, Hajo.

I: Biometrical Journal, Bind 47, Nr. 2, 04.2005, s. 237-47.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

TY - JOUR

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T2 - using confidence curves in medical research

AU - Bender, Ralf

AU - Berg, Gabriele

AU - Zeeb, Hajo

PY - 2005/4

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N2 - Confidence intervals represent a routinely used standard method to document the uncertainty of estimated effects. In most cases, for the calculation of confidence intervals the conventional fixed 95% confidence level is used. Confidence curves represent a graphical illustration of confidence intervals for confidence levels varying between 0 and 100%. Although such graphs have been repeatedly proposed under different names during the last 40 years, confidence curves are rarely used in medical research. In this paper, we introduce confidence curves and present a short historical review. We draw attention to the different interpretation of one- and two-sided statistical inference. It is shown that these two options also have influence on the plotting of appropriate confidence curves. We illustrate the use of one- and two-sided confidence curves and explain their correct interpretation. In medical research more emphasis on the choice between the one- and two-sided approaches should be given. One- and two-sided confidence curves are useful complements to the conventional methods of presenting study results.

AB - Confidence intervals represent a routinely used standard method to document the uncertainty of estimated effects. In most cases, for the calculation of confidence intervals the conventional fixed 95% confidence level is used. Confidence curves represent a graphical illustration of confidence intervals for confidence levels varying between 0 and 100%. Although such graphs have been repeatedly proposed under different names during the last 40 years, confidence curves are rarely used in medical research. In this paper, we introduce confidence curves and present a short historical review. We draw attention to the different interpretation of one- and two-sided statistical inference. It is shown that these two options also have influence on the plotting of appropriate confidence curves. We illustrate the use of one- and two-sided confidence curves and explain their correct interpretation. In medical research more emphasis on the choice between the one- and two-sided approaches should be given. One- and two-sided confidence curves are useful complements to the conventional methods of presenting study results.

KW - Animals

KW - Biometry

KW - Cattle

KW - Confidence Intervals

KW - Decision Making, Computer-Assisted

KW - Humans

KW - Melanoma

KW - Models, Statistical

KW - Research Design

KW - Risk Factors

KW - Superinfection

KW - Survival Analysis

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VL - 47

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JO - Biometrical Journal

JF - Biometrical Journal

SN - 0323-3847

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