Tumor-site specific geometric distortions in high field integrated magnetic resonance linear accelerator radiotherapy

Signe Winther Hasler; Uffe Bernchou; Anders Bertelsen; Elisabeth van Veldhuizen; Tine Schytte; Vibeke Nordmark Hansen; Carsten Brink; Faisal Mahmood

doi:10.1016/j.phro.2020.07.007

Tumor-site specific geometric distortions in high field integrated magnetic resonance linear accelerator radiotherapy

Signe Winther Hasler^*
, Uffe Bernchou
, Anders Bertelsen
, Elisabeth van Veldhuizen
, Tine Schytte
, Vibeke Nordmark Hansen
, Carsten Brink
, Faisal Mahmood

^*Kontaktforfatter

KI, OUH, Forskningsenhed for Onkologi (Odense)

Odense Universitetshospital

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

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Abstract

Magnetic resonance imaging (MRI) has exquisite soft-tissue contrast and is the foundation for image guided radiotherapy (IGRT) with integrated magnetic resonance linacs. However, MRI suffers from geometrical distortions. In this study the MRI system- and patient-induced geometric distortion at four different tumor-sites was investigated: adrenal gland (7 patients), liver (4 patients), pancreas (6 patients), prostate (20 patients). Maximum level of total distortion within the gross-tumor-volume (GTV) was 0.96 mm with no significant difference between abdominal patients (adrenal gland, liver, pancreas) and pelvic patients (prostate). Total tumor-site specific distortion depended on location in the field-of-view and increased with the distance to MRI iso-center.

Originalsprog	Engelsk
Tidsskrift	Physics and Imaging in Radiation Oncology
Vol/bind	15
Sider (fra-til)	100-104
ISSN	2405-6316
DOI	https://doi.org/10.1016/j.phro.2020.07.007
Status	Udgivet - jul. 2020

Finansiering

This work is supported by DCCC Radiotherapy - The Danish National Research Center for Radiotherapy, Danish Cancer Society (grant no. R191-A11526 ) and Danish Comprehensive Cancer Center , OUH & RH Research Fund (grant no. 58-A2857 ) and the Danish Cancer Society (grant no. R231-A13852 ). The funding sources have no other involvement than financial support.

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10.1016/j.phro.2020.07.007Licens: CC BY-NC-ND

Open Access VersionForlagets udgivne version, 2,42 MBLicens: CC BY-NC-ND

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1 Ph.d.-afhandling

Investigating geometric distortions in MRI used for radiotherapy: A national study
Bidragets oversatte titel: Undersøgelse af geometriske forvrængninger i MR billeder brugt i stråleterapi: Et nationalt studieHasler, S. W., 7. feb. 2024, Syddansk Universitet. Det Sundhedsvidenskabelige Fakultet. 131 s.
Publikation: Afhandling › Ph.d.-afhandling

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Citationsformater

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title = "Tumor-site specific geometric distortions in high field integrated magnetic resonance linear accelerator radiotherapy",

abstract = "Magnetic resonance imaging (MRI) has exquisite soft-tissue contrast and is the foundation for image guided radiotherapy (IGRT) with integrated magnetic resonance linacs. However, MRI suffers from geometrical distortions. In this study the MRI system- and patient-induced geometric distortion at four different tumor-sites was investigated: adrenal gland (7 patients), liver (4 patients), pancreas (6 patients), prostate (20 patients). Maximum level of total distortion within the gross-tumor-volume (GTV) was 0.96 mm with no significant difference between abdominal patients (adrenal gland, liver, pancreas) and pelvic patients (prostate). Total tumor-site specific distortion depended on location in the field-of-view and increased with the distance to MRI iso-center.",

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author = "Hasler, \{Signe Winther\} and Uffe Bernchou and Anders Bertelsen and \{van Veldhuizen\}, Elisabeth and Tine Schytte and Hansen, \{Vibeke Nordmark\} and Carsten Brink and Faisal Mahmood",

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T1 - Tumor-site specific geometric distortions in high field integrated magnetic resonance linear accelerator radiotherapy

AU - Hasler, Signe Winther

AU - Bernchou, Uffe

AU - Bertelsen, Anders

AU - van Veldhuizen, Elisabeth

AU - Schytte, Tine

AU - Hansen, Vibeke Nordmark

AU - Brink, Carsten

AU - Mahmood, Faisal

PY - 2020/7

Y1 - 2020/7

N2 - Magnetic resonance imaging (MRI) has exquisite soft-tissue contrast and is the foundation for image guided radiotherapy (IGRT) with integrated magnetic resonance linacs. However, MRI suffers from geometrical distortions. In this study the MRI system- and patient-induced geometric distortion at four different tumor-sites was investigated: adrenal gland (7 patients), liver (4 patients), pancreas (6 patients), prostate (20 patients). Maximum level of total distortion within the gross-tumor-volume (GTV) was 0.96 mm with no significant difference between abdominal patients (adrenal gland, liver, pancreas) and pelvic patients (prostate). Total tumor-site specific distortion depended on location in the field-of-view and increased with the distance to MRI iso-center.

AB - Magnetic resonance imaging (MRI) has exquisite soft-tissue contrast and is the foundation for image guided radiotherapy (IGRT) with integrated magnetic resonance linacs. However, MRI suffers from geometrical distortions. In this study the MRI system- and patient-induced geometric distortion at four different tumor-sites was investigated: adrenal gland (7 patients), liver (4 patients), pancreas (6 patients), prostate (20 patients). Maximum level of total distortion within the gross-tumor-volume (GTV) was 0.96 mm with no significant difference between abdominal patients (adrenal gland, liver, pancreas) and pelvic patients (prostate). Total tumor-site specific distortion depended on location in the field-of-view and increased with the distance to MRI iso-center.

KW - Adaptive radiotherapy

KW - Geometric distortion

KW - MR guided radiotherapy

KW - MR-linac

KW - MRI

KW - QA

U2 - 10.1016/j.phro.2020.07.007

DO - 10.1016/j.phro.2020.07.007

M3 - Journal article

C2 - 33458333

AN - SCOPUS:85089497461

SN - 2405-6316

VL - 15

SP - 100

EP - 104

JO - Physics and Imaging in Radiation Oncology

JF - Physics and Imaging in Radiation Oncology

ER -

Tumor-site specific geometric distortions in high field integrated magnetic resonance linear accelerator radiotherapy

Abstract

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Investigating geometric distortions in MRI used for radiotherapy: A national study

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