TY - JOUR
T1 - Three-year changes in fitness and adiposity are independently associated with cardiovascular risk factors among young danish children
AU - Jago, Russell
AU - Froberg, Karsten
AU - Cooper, Ashley R
AU - Eiberg, Stig
AU - Andersen, Lars Bo
PY - 2010/1/1
Y1 - 2010/1/1
N2 - BACKGROUND: It is not clear the extent to which change in adiposity and cardiovascular fitness (CRF) during early childhood are associated with change in cardiovascular risk factors or if associations are independent or interactive. METHODS: 383 Danish children were examined at ages 6 and 9. CRF, sum of skinfolds (SSF), and blood pressure were assessed. Fasting blood samples were used to calculate total cholesterol (TC), high and low density lipoprotein cholesterol (HDL-C & LDL-C), triglycerides, insulin, glucose, and HOMA-IR. Regression models examined whether CRF change or SSF change were independently or interactively associated with risk variables. RESULTS: Change in SSF was independently associated with change in TC (z = 4.83, P < .001), LDL-C (z = 4.38, P < .001), systolic (z = 3.45, P < .001), and diastolic (z = 2.45, P = .014) blood pressure. CRF change was independently associated with change in TC (z = -3.86, P < .001), HDL-C (z = 3.85, P < .001), and systolic blood pressure (z = 2.06, P = .040). CONCLUSIONS: Change in fitness and adiposity were independently associated with the development of cardiovascular risk factors among young children suggesting a need to increase CRF and prevent weight gain early during development to improve cardiovascular health.
AB - BACKGROUND: It is not clear the extent to which change in adiposity and cardiovascular fitness (CRF) during early childhood are associated with change in cardiovascular risk factors or if associations are independent or interactive. METHODS: 383 Danish children were examined at ages 6 and 9. CRF, sum of skinfolds (SSF), and blood pressure were assessed. Fasting blood samples were used to calculate total cholesterol (TC), high and low density lipoprotein cholesterol (HDL-C & LDL-C), triglycerides, insulin, glucose, and HOMA-IR. Regression models examined whether CRF change or SSF change were independently or interactively associated with risk variables. RESULTS: Change in SSF was independently associated with change in TC (z = 4.83, P < .001), LDL-C (z = 4.38, P < .001), systolic (z = 3.45, P < .001), and diastolic (z = 2.45, P = .014) blood pressure. CRF change was independently associated with change in TC (z = -3.86, P < .001), HDL-C (z = 3.85, P < .001), and systolic blood pressure (z = 2.06, P = .040). CONCLUSIONS: Change in fitness and adiposity were independently associated with the development of cardiovascular risk factors among young children suggesting a need to increase CRF and prevent weight gain early during development to improve cardiovascular health.
M3 - Journal article
C2 - 20231753
SN - 1543-3080
VL - 7
SP - 37
EP - 44
JO - Journal of Physical Activity & Health
JF - Journal of Physical Activity & Health
IS - 1
ER -