The value of contrast-enhanced laparoscopic ultrasound during robotic-assisted surgery for primary colorectal cancer

Signe Bremholm Ellebaek, Claus Wilki Fristrup, Torsten Pless, Peiman Hossein Poornoroozy, Per Vadgaard Andersen, Bassam Mahdi, Michael Bau Mortensen

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Resumé

AIM: The aim of this study was to assess the potential clinical value of contrast enhanced laparoscopic ultrasonography (CE-LUS) as a screening modality for liver metastases during robotic assisted surgery for primary colorectal cancer (CRC).

METHOD: A prospective, descriptive (feasibility) study including 50 consecutive patients scheduled for robotic assisted surgery for primary CRC. CE-LUS was performed by 2 experienced specialists. Only patients without metastatic disease were included. Follow-up was obtained with contrast-enhanced CT imaging at 3 and 12 months postoperatively.

RESULTS: Fifty patients were included; 45 patients were available for final analysis. The patients were equally distributed between stage I, II, and III according to the TNM classification system. No liver metastasis was detected during LUS and CE-LUS. CE-LUS was easy to perform and there was no complication. Follow-up revealed no liver metastasis in any of the patients.

CONCLUSION: CE-LUS did not increase the detection rate of occult liver metastasis during robotic assisted primary CRC surgery. The use of CE-LUS as a screening modality for detection of liver metastasis cannot be recommended based on this study, but larger controlled studies on high-risk patients seem relevant.

OriginalsprogEngelsk
TidsskriftJournal of Clinical Ultrasound
Vol/bind46
Udgave nummer3
Sider (fra-til)178-182
ISSN0091-2751
DOI
StatusUdgivet - mar. 2018

Fingeraftryk

Robotics
Colorectal Neoplasms
Ultrasonography
Liver
Colorectal Surgery
Neoplasm Staging
Feasibility Studies

Citer dette

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title = "The value of contrast-enhanced laparoscopic ultrasound during robotic-assisted surgery for primary colorectal cancer",
abstract = "AIM: The aim of this study was to assess the potential clinical value of contrast enhanced laparoscopic ultrasonography (CE-LUS) as a screening modality for liver metastases during robotic assisted surgery for primary colorectal cancer (CRC).METHOD: A prospective, descriptive (feasibility) study including 50 consecutive patients scheduled for robotic assisted surgery for primary CRC. CE-LUS was performed by 2 experienced specialists. Only patients without metastatic disease were included. Follow-up was obtained with contrast-enhanced CT imaging at 3 and 12 months postoperatively.RESULTS: Fifty patients were included; 45 patients were available for final analysis. The patients were equally distributed between stage I, II, and III according to the TNM classification system. No liver metastasis was detected during LUS and CE-LUS. CE-LUS was easy to perform and there was no complication. Follow-up revealed no liver metastasis in any of the patients.CONCLUSION: CE-LUS did not increase the detection rate of occult liver metastasis during robotic assisted primary CRC surgery. The use of CE-LUS as a screening modality for detection of liver metastasis cannot be recommended based on this study, but larger controlled studies on high-risk patients seem relevant.",
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author = "Ellebaek, {Signe Bremholm} and Fristrup, {Claus Wilki} and Torsten Pless and Poornoroozy, {Peiman Hossein} and Andersen, {Per Vadgaard} and Bassam Mahdi and Mortensen, {Michael Bau}",
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The value of contrast-enhanced laparoscopic ultrasound during robotic-assisted surgery for primary colorectal cancer. / Ellebaek, Signe Bremholm; Fristrup, Claus Wilki; Pless, Torsten; Poornoroozy, Peiman Hossein; Andersen, Per Vadgaard; Mahdi, Bassam; Mortensen, Michael Bau.

I: Journal of Clinical Ultrasound, Bind 46, Nr. 3, 03.2018, s. 178-182.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

TY - JOUR

T1 - The value of contrast-enhanced laparoscopic ultrasound during robotic-assisted surgery for primary colorectal cancer

AU - Ellebaek, Signe Bremholm

AU - Fristrup, Claus Wilki

AU - Pless, Torsten

AU - Poornoroozy, Peiman Hossein

AU - Andersen, Per Vadgaard

AU - Mahdi, Bassam

AU - Mortensen, Michael Bau

N1 - © 2017 Wiley Periodicals, Inc.

PY - 2018/3

Y1 - 2018/3

N2 - AIM: The aim of this study was to assess the potential clinical value of contrast enhanced laparoscopic ultrasonography (CE-LUS) as a screening modality for liver metastases during robotic assisted surgery for primary colorectal cancer (CRC).METHOD: A prospective, descriptive (feasibility) study including 50 consecutive patients scheduled for robotic assisted surgery for primary CRC. CE-LUS was performed by 2 experienced specialists. Only patients without metastatic disease were included. Follow-up was obtained with contrast-enhanced CT imaging at 3 and 12 months postoperatively.RESULTS: Fifty patients were included; 45 patients were available for final analysis. The patients were equally distributed between stage I, II, and III according to the TNM classification system. No liver metastasis was detected during LUS and CE-LUS. CE-LUS was easy to perform and there was no complication. Follow-up revealed no liver metastasis in any of the patients.CONCLUSION: CE-LUS did not increase the detection rate of occult liver metastasis during robotic assisted primary CRC surgery. The use of CE-LUS as a screening modality for detection of liver metastasis cannot be recommended based on this study, but larger controlled studies on high-risk patients seem relevant.

AB - AIM: The aim of this study was to assess the potential clinical value of contrast enhanced laparoscopic ultrasonography (CE-LUS) as a screening modality for liver metastases during robotic assisted surgery for primary colorectal cancer (CRC).METHOD: A prospective, descriptive (feasibility) study including 50 consecutive patients scheduled for robotic assisted surgery for primary CRC. CE-LUS was performed by 2 experienced specialists. Only patients without metastatic disease were included. Follow-up was obtained with contrast-enhanced CT imaging at 3 and 12 months postoperatively.RESULTS: Fifty patients were included; 45 patients were available for final analysis. The patients were equally distributed between stage I, II, and III according to the TNM classification system. No liver metastasis was detected during LUS and CE-LUS. CE-LUS was easy to perform and there was no complication. Follow-up revealed no liver metastasis in any of the patients.CONCLUSION: CE-LUS did not increase the detection rate of occult liver metastasis during robotic assisted primary CRC surgery. The use of CE-LUS as a screening modality for detection of liver metastasis cannot be recommended based on this study, but larger controlled studies on high-risk patients seem relevant.

KW - Adult

KW - Aged

KW - Aged, 80 and over

KW - Colon/diagnostic imaging

KW - Colorectal Neoplasms/diagnostic imaging

KW - Contrast Media

KW - Feasibility Studies

KW - Female

KW - Follow-Up Studies

KW - Humans

KW - Image Enhancement/methods

KW - Laparoscopy/methods

KW - Male

KW - Middle Aged

KW - Prospective Studies

KW - Rectum/diagnostic imaging

KW - Robotic Surgical Procedures/methods

KW - Ultrasonography/methods

U2 - 10.1002/jcu.22560

DO - 10.1002/jcu.22560

M3 - Journal article

VL - 46

SP - 178

EP - 182

JO - Journal of Clinical Ultrasound

JF - Journal of Clinical Ultrasound

SN - 0091-2751

IS - 3

ER -