The simultaneous use of 99m-Tc-HIDA scintigraphy and ultrasound in determination of gallbladder storage and emptying in the fasting state.

Niels Qvist, Søren Rafael Rafaelsen, E. Øster-Jørgensen, Lars Rasmussen, Claus Hovendal, S.A. Pedersen

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Resumé

In eight healthy fasting young men simultaneous hepatobiliary scintigraphy and ultrasonography of the gallbladder was performed using intravenous infusion of 99m-Tc-HIA administered at a rate of 40 Mbq/h. Time-activity curves over the gallbladder and intestinal area were generated. Gallbladder volume for the corresponding counting periods (each of 270 s) was measured by ultrasonography. There was good concordance (92% of the total monitoring period) between the course of the time-activity curves over the gallbladder and intestinal area with respect to describing the partitioning of bile between gallbladder and intestine. All subjects had cyclic variations in gallbladder radioactivity with episodes of filling and emptying. However, in 30% of the time with gallbladder filling at HIA-scintigraphy, ultrasonography revealed increasing gallbladder volume, and in only 46% of the time where HIA-scintigraphy showed gallbladder emptying was this accompanied by a decrease in gallbladder volume at ultrasonography. There was poor correlation between biliary flow to and from the gallbladder, as well as changes in gallbladder volume. This does not necessarily suggest a difference in sensitivity between scintigraphy and ultrasonography, because fluid transport across the gallbladder epithelium could alter the gallbladder volume without changing the scintigraphic counts obtained from the gallbladder.
OriginalsprogEngelsk
TidsskriftEuropean journal of gastroenterology & hepatology
Vol/bind3/(9)
Sider (fra-til)657-661
ISSN0954-691X
StatusUdgivet - 1991

Fingeraftryk

Gallbladder Emptying
Gallbladder
Radionuclide Imaging
Fasting
Ultrasonography
lidofenin

Citer dette

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title = "The simultaneous use of 99m-Tc-HIDA scintigraphy and ultrasound in determination of gallbladder storage and emptying in the fasting state.",
abstract = "In eight healthy fasting young men simultaneous hepatobiliary scintigraphy and ultrasonography of the gallbladder was performed using intravenous infusion of 99m-Tc-HIA administered at a rate of 40 Mbq/h. Time-activity curves over the gallbladder and intestinal area were generated. Gallbladder volume for the corresponding counting periods (each of 270 s) was measured by ultrasonography. There was good concordance (92{\%} of the total monitoring period) between the course of the time-activity curves over the gallbladder and intestinal area with respect to describing the partitioning of bile between gallbladder and intestine. All subjects had cyclic variations in gallbladder radioactivity with episodes of filling and emptying. However, in 30{\%} of the time with gallbladder filling at HIA-scintigraphy, ultrasonography revealed increasing gallbladder volume, and in only 46{\%} of the time where HIA-scintigraphy showed gallbladder emptying was this accompanied by a decrease in gallbladder volume at ultrasonography. There was poor correlation between biliary flow to and from the gallbladder, as well as changes in gallbladder volume. This does not necessarily suggest a difference in sensitivity between scintigraphy and ultrasonography, because fluid transport across the gallbladder epithelium could alter the gallbladder volume without changing the scintigraphic counts obtained from the gallbladder.",
keywords = "ultrasound, Gallbladder, volumen",
author = "Niels Qvist and Rafaelsen, {S{\o}ren Rafael} and E. {\O}ster-J{\o}rgensen and Lars Rasmussen and Claus Hovendal and S.A. Pedersen",
year = "1991",
language = "English",
volume = "3/(9)",
pages = "657--661",
journal = "European Journal of Gastroenterology and Hepatology",
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The simultaneous use of 99m-Tc-HIDA scintigraphy and ultrasound in determination of gallbladder storage and emptying in the fasting state. / Qvist, Niels; Rafaelsen, Søren Rafael; Øster-Jørgensen, E.; Rasmussen, Lars; Hovendal, Claus; Pedersen, S.A.

I: European journal of gastroenterology & hepatology, Bind 3/(9), 1991, s. 657-661.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

TY - JOUR

T1 - The simultaneous use of 99m-Tc-HIDA scintigraphy and ultrasound in determination of gallbladder storage and emptying in the fasting state.

AU - Qvist, Niels

AU - Rafaelsen, Søren Rafael

AU - Øster-Jørgensen, E.

AU - Rasmussen, Lars

AU - Hovendal, Claus

AU - Pedersen, S.A.

PY - 1991

Y1 - 1991

N2 - In eight healthy fasting young men simultaneous hepatobiliary scintigraphy and ultrasonography of the gallbladder was performed using intravenous infusion of 99m-Tc-HIA administered at a rate of 40 Mbq/h. Time-activity curves over the gallbladder and intestinal area were generated. Gallbladder volume for the corresponding counting periods (each of 270 s) was measured by ultrasonography. There was good concordance (92% of the total monitoring period) between the course of the time-activity curves over the gallbladder and intestinal area with respect to describing the partitioning of bile between gallbladder and intestine. All subjects had cyclic variations in gallbladder radioactivity with episodes of filling and emptying. However, in 30% of the time with gallbladder filling at HIA-scintigraphy, ultrasonography revealed increasing gallbladder volume, and in only 46% of the time where HIA-scintigraphy showed gallbladder emptying was this accompanied by a decrease in gallbladder volume at ultrasonography. There was poor correlation between biliary flow to and from the gallbladder, as well as changes in gallbladder volume. This does not necessarily suggest a difference in sensitivity between scintigraphy and ultrasonography, because fluid transport across the gallbladder epithelium could alter the gallbladder volume without changing the scintigraphic counts obtained from the gallbladder.

AB - In eight healthy fasting young men simultaneous hepatobiliary scintigraphy and ultrasonography of the gallbladder was performed using intravenous infusion of 99m-Tc-HIA administered at a rate of 40 Mbq/h. Time-activity curves over the gallbladder and intestinal area were generated. Gallbladder volume for the corresponding counting periods (each of 270 s) was measured by ultrasonography. There was good concordance (92% of the total monitoring period) between the course of the time-activity curves over the gallbladder and intestinal area with respect to describing the partitioning of bile between gallbladder and intestine. All subjects had cyclic variations in gallbladder radioactivity with episodes of filling and emptying. However, in 30% of the time with gallbladder filling at HIA-scintigraphy, ultrasonography revealed increasing gallbladder volume, and in only 46% of the time where HIA-scintigraphy showed gallbladder emptying was this accompanied by a decrease in gallbladder volume at ultrasonography. There was poor correlation between biliary flow to and from the gallbladder, as well as changes in gallbladder volume. This does not necessarily suggest a difference in sensitivity between scintigraphy and ultrasonography, because fluid transport across the gallbladder epithelium could alter the gallbladder volume without changing the scintigraphic counts obtained from the gallbladder.

KW - ultrasound

KW - Gallbladder

KW - volumen

M3 - Journal article

VL - 3/(9)

SP - 657

EP - 661

JO - European Journal of Gastroenterology and Hepatology

JF - European Journal of Gastroenterology and Hepatology

SN - 0954-691X

ER -