The role of baseline serum 25(OH)D concentration for a potential personalized vitamin D supplementation

Paola G. Ferrario*, Bernhard Watzl, Christian Ritz

*Kontaktforfatter

Publikation: Bidrag til tidsskriftKommentar/debatForskningpeer review

16 Downloads (Pure)

Abstract

There are many examples in clinical nutrition with individuals responding differently to a dietary intervention. Here, personalized nutritional recommendations could be targeted, tailoring interventions to address plurality in response. For this, we reconsidered two randomized controlled trials investigating whether two different supplementation doses of cholecalciferol resulted in an increased serum 25(OH)D concentration. Three different statistical methods were applied in order to identify participants who would enjoy an increased benefit from receiving a specific dose of cholecalciferol. We concluded that, for individuals with high baseline serum 25(OH)D concentrations, only the high supplementation dose will lead to a substantial increase in the serum 25(OH)D concentration. The presented statistical methods can be adequately used for more individualized approaches.

OriginalsprogEngelsk
TidsskriftEuropean Journal of Clinical Nutrition
Vol/bind76
Udgave nummer11
Sider (fra-til)1624-1629
ISSN0954-3007
DOI
StatusUdgivet - nov. 2022

Fingeraftryk

Dyk ned i forskningsemnerne om 'The role of baseline serum 25(OH)D concentration for a potential personalized vitamin D supplementation'. Sammen danner de et unikt fingeraftryk.

Citationsformater