The quantification of vaccine uptake in the Nordic countries and impact on key indicators of COVID-19 severity and healthcare stress level via age range comparative analysis

Anna Sigridur Islind, María Óskarsdóttir*, Corentin Cot, Giacomo Cacciapaglia, Francesco Sannino

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Abstract

In this paper we analyze the impact of vaccinations on spread of the COVID-19 virus for different age groups. More specifically, we examine the deployment of vaccines in the Nordic countries in a comparative analysis where we focus on factors such as healthcare stress level and severity of disease through new infections, hospitalizations, intensive care unit (ICU) occupancy and deaths. Moreover, we analyze the impact of the various vaccine types, vaccination rate on the spread of the virus in each age group for Denmark, Finland, Iceland, Norway and Sweden from the start of the vaccination period in December 2020 until the end of September 2021. We perform a threefold analysis: (i) frequency analysis of infections and vaccine rates by age groups; (ii) rolling correlations between vaccination strategies, severity of COVID-19 and healthcare stress level and; (iii) we also employ the epidemic Renormalization Group (eRG) framework. The eRG is used to mathematically model wave structures, as well as the impact of vaccinations on wave dynamics. We further compare the Nordic countries with England. Our main results outline the quantification of the impact of the vaccination campaigns on age groups epidemiological data, across countries with high vaccine uptake. The data clearly shows that vaccines markedly reduce the number of new cases and the risk of serious illness.

OriginalsprogEngelsk
Artikelnummer16891
TidsskriftScientific Reports
Vol/bind12
ISSN2045-2322
DOI
StatusUdgivet - 7. okt. 2022

Bibliografisk note

Funding Information:
European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (TransMID 682,540: CF, PN, NH).

Funding Information:
This research was partly funded by the Global Challenges Research Fund (GCRF) project RECAP managed through RCUK and ESRC (ES/P010873/1: CIJ).

Funding Information:
HPRU in Modelling & Health Economics,NIHR200908,European Union's Horizon 2020 research and innovation programme,EpiPose 101003688,TransMID 682540,TransMID 682540,TransMID 682540,EpiPose 101003688,Wellcome Trust,213589/Z/18/Z,National Institute for Health Research,CV220-088—COMIX,CV220-088—COMIX,CV220-088—COMIX,Global Challenges Research Fund,ES/P010873/1,Medical Research Council,MC_PC_19065,NIHR,PR-OD-1017-20002

Publisher Copyright:
© 2022, The Author(s).

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