Abstrakt
The pituitary-thyroid axis (PTA) set point is determined by a combination of genetic and environmental factors. However, despite considerable efforts to characterize the background, the causative genes as well as environmental factors are not well established. Theoretically, as shown for autoimmune thyroid disease, the pattern of X chromosome inactivation (XCI) could offer a novel explanation for the observed variability of the PTA set point in women.
Originalsprog | Engelsk |
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Tidsskrift | Clinical Endocrinology |
Vol/bind | 73 |
Udgave nummer | 5 |
Sider (fra-til) | 666-70 |
Antal sider | 5 |
ISSN | 0300-0664 |
DOI | |
Status | Udgivet - 1. nov. 2010 |