The Odense Child Cohort

Aims, Design, and Cohort Profile

Henriette Boye Kyhl, Tina Kold Jensen, Torben Barington, Susanne Buhl, Lene Annette Norberg, Jan Stener Jørgensen, Ditlev Frank Granhøj Jensen, Henrik Thybo Christesen, Ronald F Lamont, Steffen Husby

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Resumé

BACKGROUND: The importance of the environment on the development of the fetus and infant throughout early life is increasingly recognised. To study such effects, biological samples and accurate data records are required. Based on multiple data collection from a healthy pregnant population, the Odense Childhood Cohort (OCC) study aims to provide new information about the environmental impact on child health by sequential follow-up to 18 years of age among children born between 2010 and 2012.

METHODS: A total of 2874 of 6707 pregnancies (43%) were recruited between January 2010 and December 2012. Three hundred seventy-four have since left the study, leaving 2500 active families. The non-participants act as controls contributing data through local registries. Biological material, questionnaires, and registry data were compiled. Anthropometric data and other physical data were collected.

RESULTS: Two thousand five hundred families actively participated in the study with 2549 children. Sixty-four per cent of the fathers and 60% and 58% of the mothers, respectively, donated a blood sample at 10 and 28 weeks of gestation. On average, 69% completed questionnaires, 78% of the children were regularly examined, and had a blood sample taken (46%). The participating pregnant women differed from the non-participants in several respects: age, body mass index, smoking, parity, education, and ethnicity. The infants were comparable with respect to gender and mode of delivery.

CONCLUSIONS: The OCC provides material for in-depth analysis of environmental and genetic factors that are important for child health and disease. Registry data from non-participating women and infants are available which ensures a high degree of comparable data.

OriginalsprogEngelsk
TidsskriftPaediatric and Perinatal Epidemiology (Print)
Vol/bind29
Udgave nummer3
Sider (fra-til)250–258
ISSN0269-5022
DOI
StatusUdgivet - 10. mar. 2015

Fingeraftryk

Registries
Parity
Fathers
Pregnant Women
Body Mass Index
Fetus
Cohort Studies
Smoking
Mothers
Education
Population
Child Health
Surveys and Questionnaires

Citer dette

@article{cb79efc960a04bc6a5435c83cf16b298,
title = "The Odense Child Cohort: Aims, Design, and Cohort Profile",
abstract = "BACKGROUND: The importance of the environment on the development of the fetus and infant throughout early life is increasingly recognised. To study such effects, biological samples and accurate data records are required. Based on multiple data collection from a healthy pregnant population, the Odense Childhood Cohort (OCC) study aims to provide new information about the environmental impact on child health by sequential follow-up to 18 years of age among children born between 2010 and 2012.METHODS: A total of 2874 of 6707 pregnancies (43{\%}) were recruited between January 2010 and December 2012. Three hundred seventy-four have since left the study, leaving 2500 active families. The non-participants act as controls contributing data through local registries. Biological material, questionnaires, and registry data were compiled. Anthropometric data and other physical data were collected.RESULTS: Two thousand five hundred families actively participated in the study with 2549 children. Sixty-four per cent of the fathers and 60{\%} and 58{\%} of the mothers, respectively, donated a blood sample at 10 and 28 weeks of gestation. On average, 69{\%} completed questionnaires, 78{\%} of the children were regularly examined, and had a blood sample taken (46{\%}). The participating pregnant women differed from the non-participants in several respects: age, body mass index, smoking, parity, education, and ethnicity. The infants were comparable with respect to gender and mode of delivery.CONCLUSIONS: The OCC provides material for in-depth analysis of environmental and genetic factors that are important for child health and disease. Registry data from non-participating women and infants are available which ensures a high degree of comparable data.",
author = "Kyhl, {Henriette Boye} and Jensen, {Tina Kold} and Torben Barington and Susanne Buhl and Norberg, {Lene Annette} and J{\o}rgensen, {Jan Stener} and Jensen, {Ditlev Frank Granh{\o}j} and Christesen, {Henrik Thybo} and Lamont, {Ronald F} and Steffen Husby",
note = "{\circledC} 2015 John Wiley & Sons Ltd.",
year = "2015",
month = "3",
day = "10",
doi = "10.1111/ppe.12183",
language = "English",
volume = "29",
pages = "250–258",
journal = "Paediatric and Perinatal Epidemiology (Print)",
issn = "0269-5022",
publisher = "Wiley-Blackwell",
number = "3",

}

The Odense Child Cohort : Aims, Design, and Cohort Profile. / Kyhl, Henriette Boye; Jensen, Tina Kold; Barington, Torben; Buhl, Susanne; Norberg, Lene Annette; Jørgensen, Jan Stener; Jensen, Ditlev Frank Granhøj; Christesen, Henrik Thybo; Lamont, Ronald F; Husby, Steffen.

I: Paediatric and Perinatal Epidemiology (Print), Bind 29, Nr. 3, 10.03.2015, s. 250–258.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

TY - JOUR

T1 - The Odense Child Cohort

T2 - Aims, Design, and Cohort Profile

AU - Kyhl, Henriette Boye

AU - Jensen, Tina Kold

AU - Barington, Torben

AU - Buhl, Susanne

AU - Norberg, Lene Annette

AU - Jørgensen, Jan Stener

AU - Jensen, Ditlev Frank Granhøj

AU - Christesen, Henrik Thybo

AU - Lamont, Ronald F

AU - Husby, Steffen

N1 - © 2015 John Wiley & Sons Ltd.

PY - 2015/3/10

Y1 - 2015/3/10

N2 - BACKGROUND: The importance of the environment on the development of the fetus and infant throughout early life is increasingly recognised. To study such effects, biological samples and accurate data records are required. Based on multiple data collection from a healthy pregnant population, the Odense Childhood Cohort (OCC) study aims to provide new information about the environmental impact on child health by sequential follow-up to 18 years of age among children born between 2010 and 2012.METHODS: A total of 2874 of 6707 pregnancies (43%) were recruited between January 2010 and December 2012. Three hundred seventy-four have since left the study, leaving 2500 active families. The non-participants act as controls contributing data through local registries. Biological material, questionnaires, and registry data were compiled. Anthropometric data and other physical data were collected.RESULTS: Two thousand five hundred families actively participated in the study with 2549 children. Sixty-four per cent of the fathers and 60% and 58% of the mothers, respectively, donated a blood sample at 10 and 28 weeks of gestation. On average, 69% completed questionnaires, 78% of the children were regularly examined, and had a blood sample taken (46%). The participating pregnant women differed from the non-participants in several respects: age, body mass index, smoking, parity, education, and ethnicity. The infants were comparable with respect to gender and mode of delivery.CONCLUSIONS: The OCC provides material for in-depth analysis of environmental and genetic factors that are important for child health and disease. Registry data from non-participating women and infants are available which ensures a high degree of comparable data.

AB - BACKGROUND: The importance of the environment on the development of the fetus and infant throughout early life is increasingly recognised. To study such effects, biological samples and accurate data records are required. Based on multiple data collection from a healthy pregnant population, the Odense Childhood Cohort (OCC) study aims to provide new information about the environmental impact on child health by sequential follow-up to 18 years of age among children born between 2010 and 2012.METHODS: A total of 2874 of 6707 pregnancies (43%) were recruited between January 2010 and December 2012. Three hundred seventy-four have since left the study, leaving 2500 active families. The non-participants act as controls contributing data through local registries. Biological material, questionnaires, and registry data were compiled. Anthropometric data and other physical data were collected.RESULTS: Two thousand five hundred families actively participated in the study with 2549 children. Sixty-four per cent of the fathers and 60% and 58% of the mothers, respectively, donated a blood sample at 10 and 28 weeks of gestation. On average, 69% completed questionnaires, 78% of the children were regularly examined, and had a blood sample taken (46%). The participating pregnant women differed from the non-participants in several respects: age, body mass index, smoking, parity, education, and ethnicity. The infants were comparable with respect to gender and mode of delivery.CONCLUSIONS: The OCC provides material for in-depth analysis of environmental and genetic factors that are important for child health and disease. Registry data from non-participating women and infants are available which ensures a high degree of comparable data.

U2 - 10.1111/ppe.12183

DO - 10.1111/ppe.12183

M3 - Journal article

VL - 29

SP - 250

EP - 258

JO - Paediatric and Perinatal Epidemiology (Print)

JF - Paediatric and Perinatal Epidemiology (Print)

SN - 0269-5022

IS - 3

ER -