The first woman to give birth to two children following transplantation of frozen/thawed ovarian tissue

Erik Ernst, Stinne Bergholdt, Jan Stener Jørgensen, Claus Yding Andersen

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Worldwide eight children have been born as a result of transplanting frozen/thawed ovarian tissue. Two of these children were born in Denmark following transport of the ovarian tissue for a period of 5 h prior to cryopreservation. One of these women, who was originally transplanted with six pieces of ovarian cortex, after having experienced a period of menopause has now conceived again following natural conception. She gave birth to a healthy girl on 23 September 2008 and is therefore the first woman in the world to have had two children, from separate pregnancies, born as a result of transplanting frozen/thawed ovarian tissue. This result encourages further development of cryopreservation of ovarian tissue for fertility preservation as a clinical procedure for girls and young women facing gonadotoxic treatment.
TidsskriftHuman Reproduction
Udgave nummer5
Sider (fra-til)1280-1
Antal sider2
StatusUdgivet - 1. maj 2010