The effect of dietary calcium and phosphorus supplementation in zeolite a treated dry cows on periparturient calcium and phosphorus homeostasis

Trine Thilsing, T Larsen, R J Jørgensen, H Houe

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Resumé

Previous studies have proved the possibility of preventing parturient hypocalcaemia by zeolite A supplementation during the dry period, and a recent in vitro study has indicated a marked calcium (Ca) as well as phosphorus (P) binding effect of zeolite A in rumen fluid solutions. Because of the connection between the Ca and P homeostatic systems, the preventive effect against parturient hypocalcaemia may arise from zeolite induced decreased availability of dietary Ca as well as P. In the present study, the expected Ca and P binding capacity was challenged by feeding high and low levels of dietary Ca and/or P to zeolite A treated dry cows. Twenty-one pregnant dry cows were assigned to four experimental groups receiving a dry cow ration unsupplemented or supplemented with extra Ca and/or P. During the last 2 weeks of the dry period all cows additionally received 600 g of zeolite A per day. A high level of dietary P prepartum significantly decreased the plasma Ca concentration before as well as immediately after calving (day 0-3). Conversely, the plasma inorganic phosphate concentration was higher among these cows than among cows receiving no supplemental P. The prepartum dietary Ca level significantly affected the serum 1,25-dihydroxyvitamin D concentration during zeolite supplementation, whereas the periparturient plasma Ca concentration was apparently not affected by the dietary Ca level. During zeolite A supplementation plasma parathyroid hormone was significantly higher among cows receiving additional P. The urinary deoxypyridinoline/creatinine ratio was not affected by the prepartal dietary Ca or P level. Serum aluminium (Al) was significantly higher during zeolite A supplementation than during the preceding period, indicating partial destruction of the zeolite in the intestinal tract with subsequent release and absorption of Al. It is suggested that the effect of prepartum zeolite supplementation on the periparturient Ca homeostasis depends on the level of Ca as well as P in the dry cow ration.
OriginalsprogEngelsk
TidsskriftTransboundary and Emerging Diseases
Vol/bind54
Udgave nummer2
Sider (fra-til)82-91
Antal sider10
ISSN1865-1674
DOI
StatusUdgivet - 1. mar. 2007

Fingeraftryk

Dietary Phosphorus
Zeolites
Phosphorus
homeostasis
Homeostasis
calcium
cows
phosphorus
Aluminum
dry period (lactation)
hypocalcemia
aluminum
Rumen
Parathyroid Hormone
Serum
parathyroid hormone
Creatinine
binding capacity
rumen fluids

Citer dette

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title = "The effect of dietary calcium and phosphorus supplementation in zeolite a treated dry cows on periparturient calcium and phosphorus homeostasis",
abstract = "Previous studies have proved the possibility of preventing parturient hypocalcaemia by zeolite A supplementation during the dry period, and a recent in vitro study has indicated a marked calcium (Ca) as well as phosphorus (P) binding effect of zeolite A in rumen fluid solutions. Because of the connection between the Ca and P homeostatic systems, the preventive effect against parturient hypocalcaemia may arise from zeolite induced decreased availability of dietary Ca as well as P. In the present study, the expected Ca and P binding capacity was challenged by feeding high and low levels of dietary Ca and/or P to zeolite A treated dry cows. Twenty-one pregnant dry cows were assigned to four experimental groups receiving a dry cow ration unsupplemented or supplemented with extra Ca and/or P. During the last 2 weeks of the dry period all cows additionally received 600 g of zeolite A per day. A high level of dietary P prepartum significantly decreased the plasma Ca concentration before as well as immediately after calving (day 0-3). Conversely, the plasma inorganic phosphate concentration was higher among these cows than among cows receiving no supplemental P. The prepartum dietary Ca level significantly affected the serum 1,25-dihydroxyvitamin D concentration during zeolite supplementation, whereas the periparturient plasma Ca concentration was apparently not affected by the dietary Ca level. During zeolite A supplementation plasma parathyroid hormone was significantly higher among cows receiving additional P. The urinary deoxypyridinoline/creatinine ratio was not affected by the prepartal dietary Ca or P level. Serum aluminium (Al) was significantly higher during zeolite A supplementation than during the preceding period, indicating partial destruction of the zeolite in the intestinal tract with subsequent release and absorption of Al. It is suggested that the effect of prepartum zeolite supplementation on the periparturient Ca homeostasis depends on the level of Ca as well as P in the dry cow ration.",
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The effect of dietary calcium and phosphorus supplementation in zeolite a treated dry cows on periparturient calcium and phosphorus homeostasis. / Thilsing, Trine; Larsen, T; Jørgensen, R J; Houe, H.

I: Transboundary and Emerging Diseases, Bind 54, Nr. 2, 01.03.2007, s. 82-91.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

TY - JOUR

T1 - The effect of dietary calcium and phosphorus supplementation in zeolite a treated dry cows on periparturient calcium and phosphorus homeostasis

AU - Thilsing, Trine

AU - Larsen, T

AU - Jørgensen, R J

AU - Houe, H

PY - 2007/3/1

Y1 - 2007/3/1

N2 - Previous studies have proved the possibility of preventing parturient hypocalcaemia by zeolite A supplementation during the dry period, and a recent in vitro study has indicated a marked calcium (Ca) as well as phosphorus (P) binding effect of zeolite A in rumen fluid solutions. Because of the connection between the Ca and P homeostatic systems, the preventive effect against parturient hypocalcaemia may arise from zeolite induced decreased availability of dietary Ca as well as P. In the present study, the expected Ca and P binding capacity was challenged by feeding high and low levels of dietary Ca and/or P to zeolite A treated dry cows. Twenty-one pregnant dry cows were assigned to four experimental groups receiving a dry cow ration unsupplemented or supplemented with extra Ca and/or P. During the last 2 weeks of the dry period all cows additionally received 600 g of zeolite A per day. A high level of dietary P prepartum significantly decreased the plasma Ca concentration before as well as immediately after calving (day 0-3). Conversely, the plasma inorganic phosphate concentration was higher among these cows than among cows receiving no supplemental P. The prepartum dietary Ca level significantly affected the serum 1,25-dihydroxyvitamin D concentration during zeolite supplementation, whereas the periparturient plasma Ca concentration was apparently not affected by the dietary Ca level. During zeolite A supplementation plasma parathyroid hormone was significantly higher among cows receiving additional P. The urinary deoxypyridinoline/creatinine ratio was not affected by the prepartal dietary Ca or P level. Serum aluminium (Al) was significantly higher during zeolite A supplementation than during the preceding period, indicating partial destruction of the zeolite in the intestinal tract with subsequent release and absorption of Al. It is suggested that the effect of prepartum zeolite supplementation on the periparturient Ca homeostasis depends on the level of Ca as well as P in the dry cow ration.

AB - Previous studies have proved the possibility of preventing parturient hypocalcaemia by zeolite A supplementation during the dry period, and a recent in vitro study has indicated a marked calcium (Ca) as well as phosphorus (P) binding effect of zeolite A in rumen fluid solutions. Because of the connection between the Ca and P homeostatic systems, the preventive effect against parturient hypocalcaemia may arise from zeolite induced decreased availability of dietary Ca as well as P. In the present study, the expected Ca and P binding capacity was challenged by feeding high and low levels of dietary Ca and/or P to zeolite A treated dry cows. Twenty-one pregnant dry cows were assigned to four experimental groups receiving a dry cow ration unsupplemented or supplemented with extra Ca and/or P. During the last 2 weeks of the dry period all cows additionally received 600 g of zeolite A per day. A high level of dietary P prepartum significantly decreased the plasma Ca concentration before as well as immediately after calving (day 0-3). Conversely, the plasma inorganic phosphate concentration was higher among these cows than among cows receiving no supplemental P. The prepartum dietary Ca level significantly affected the serum 1,25-dihydroxyvitamin D concentration during zeolite supplementation, whereas the periparturient plasma Ca concentration was apparently not affected by the dietary Ca level. During zeolite A supplementation plasma parathyroid hormone was significantly higher among cows receiving additional P. The urinary deoxypyridinoline/creatinine ratio was not affected by the prepartal dietary Ca or P level. Serum aluminium (Al) was significantly higher during zeolite A supplementation than during the preceding period, indicating partial destruction of the zeolite in the intestinal tract with subsequent release and absorption of Al. It is suggested that the effect of prepartum zeolite supplementation on the periparturient Ca homeostasis depends on the level of Ca as well as P in the dry cow ration.

KW - Animal Nutritional Physiological Phenomena

KW - Animals

KW - Calcium

KW - Calcium, Dietary

KW - Cattle

KW - Cattle Diseases

KW - Dietary Supplements

KW - Female

KW - Hypocalcemia

KW - Nutritional Requirements

KW - Parturition

KW - Phosphorus

KW - Phosphorus, Dietary

KW - Pregnancy

KW - Zeolites

U2 - 10.1111/j.1439-0442.2007.00887.x

DO - 10.1111/j.1439-0442.2007.00887.x

M3 - Journal article

VL - 54

SP - 82

EP - 91

JO - Transboundary and Emerging Diseases

JF - Transboundary and Emerging Diseases

SN - 1865-1674

IS - 2

ER -