The continuous separation of molecules on the basis of their polarizability using optical electric fields

Nicolas Javier Alvarez, Claus Jeppesen, Kresten Yvind, N. Asger Mortensen, Iwao Teraoka, Ole Hassager

Publikation: Konferencebidrag uden forlag/tidsskriftKonferenceabstrakt til konferenceForskningpeer review

42 Downloads (Pure)

Abstract

We introduce a new and revolutionary way to separate macromolecules. The principle is to use light to selectively retain some molecules over others depending on their differential interaction with optical fields. We call the method Photonic Waveguide Chromatography (PWC), as it combines photonic waveguides and a flow channel that constitutes a ”column” of conventional liquid chromatography. This presentation will focus on the underlying physics and our current theoretical efforts to characterize the parameter space of this process: considering both the design of the optical electric fields and the fluid dynamics needed to effectively separate molecules. This new method has a higher selectivity than traditional techniques and avoids the problem of fouling. The theoretical separation efficiency and resolution of PWC will be compared to other chromatographic techniques for various macromolecular and biological systems.
OriginalsprogEngelsk
Publikationsdato2012
Antal sider1
StatusUdgivet - 2012
Udgivet eksterntJa
Begivenhed6th Conference of the International Marangoni Association: Interfacial Fluid Dynamics and Processes - Technion University, Haifa, Israel
Varighed: 18. jun. 201222. jun. 2012
Konferencens nummer: 6
http://ima6.technion.ac.il/

Konference

Konference6th Conference of the International Marangoni Association
Nummer6
LokationTechnion University
Land/OmrådeIsrael
ByHaifa
Periode18/06/201222/06/2012
Internetadresse

Fingeraftryk

Dyk ned i forskningsemnerne om 'The continuous separation of molecules on the basis of their polarizability using optical electric fields'. Sammen danner de et unikt fingeraftryk.

Citationsformater