The circadian variation in Anti-Müllerian hormone in patients with polycystic ovary syndrome differs significantly from normally ovulating women

Leif Johan Bungum, Florencia Franssohn, Mona Berger Håkonsen Bungum, Peter Humaidan, Aleksander Giwercman

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Abstrakt

To improve the biologic understanding of the Polycystic Ovarian Syndrome (PCOS) condition by examining the circadian variation and relationship between Anti Müllerian Hormone (AMH), gonadotropins and ovarian steroids in PCOS patients compared to normally ovulating and menstruating women. By comparing the pattern of co-variation between AMH and Luteinizing Hormone, two compounds closely linked to hyperandrogenism and anovulation in PCOS, the involvement of the Hypothalamic-Pituitary-Ovarian axis in PCOS pathology could be elucidated.
OriginalsprogEngelsk
Artikelnummere68223
TidsskriftPLOS ONE
Vol/bind8
Udgave nummer9
ISSN1932-6203
DOI
StatusUdgivet - 2013

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