The bactericidal action of benzoic acid and sodium acetate on the gram-negative flora of dialysis fluid

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Abstrakt

Benzoic acid in concentrations from 0.18 per cent and upwards exerted a bactericidal action on the gram-negative flora of dialysis fluid at pH 4.75 in vitro. At a concentration of 0.32 per cent, a reduction of 10(5) was obtained with 24 hours. Sulphonamide resistance did not affect the bactericidal action. The killing effect was hardly more than directly proportional to the concentration of benzoic acid. Increasing inoculum decreased the bactericidal effect. Therefore, benbzoic acid should not be used as an artificial kidney disinfectant when the concentration of microorganisms exceeded 10(5.5)/0.1 ml.

OriginalsprogEngelsk
TidsskriftActa pathologica et microbiologica Scandinavica. Section B, Microbiology
Vol/bind84B
Udgave nummer5
Sider (fra-til)259-64
Antal sider6
ISSN0105-0656
StatusUdgivet - 1976
Udgivet eksterntJa

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