Temporal trends in survival after out-of-hospital cardiac arrest in patients with and without underlying chronic obstructive pulmonary disease

Sidsel G. Møller, Shahzleen Rajan, Frederik Folke, Carolina Malta Hansen, Steen Møller Hansen, Kristian Kragholm, Freddy K Lippert, Lars Karlsson, Lars Køber, Christian Torp-Pedersen, G. H. Gislason, Mads Wissenberg

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

    Abstrakt

    Aim: Survival after out-of-hospital cardiac arrest (OHCA) has tripled during the past decade in Denmark as a likely result of improvements in cardiac arrest management. This study analyzed whether these improvements were applicable for patients with chronic obstructive pulmonary disease (COPD). Methods: Patients ≥18 years with OHCA of presumed cardiac cause were identified through the Danish Cardiac Arrest Registry, 2001-2011. Patients with a history of COPD up to ten years prior to arrest were identified from the Danish National Patient Register and compared to non-COPD patients. Results: Of 21,480 included patients, 3056 (14.2%) had history of COPD. Compared to non-COPD patients, COPD patients were older (75 vs. 71 years), less likely male (61.2% vs. 68.5%), had higher prevalence of other comorbidities, and were less likely to have: arrests outside private homes (17.7% vs. 28.3%), witnessed arrests (48.7% vs. 52.9%), bystander cardiopulmonary resuscitation (25.8% vs. 34.8%), and shockable heart rhythm (15.6% vs. 29.9%), all p <0.001; while no significant difference in the time-interval from recognition of arrest to rhythm analysis by ambulance-crew; p = 0.24. From 2001 to 2011, survival upon hospital arrival increased in both patient-groups (from 6.8% to 17.1% in COPD patients and from 8.2% to 25.6% in non-COPD patients, p <0.001). However, no significant change was observed in 30-day survival in COPD patients (from 3.7% to 2.1%, p = 0.27), in contrast to non-COPD patients (from 3.5% to 13.0%, p <0.001). Conclusions: Despite generally improved 30-day survival after OHCA over time, no improvement was observed in 30-day survival in COPD patients. © 2016 Elsevier Ireland Ltd.
    OriginalsprogEngelsk
    TidsskriftResuscitation
    Vol/bind104
    Sider (fra-til)76-82
    ISSN0300-9572
    DOI
    StatusUdgivet - 2016

    Bibliografisk note

    Export Date: 22 March 2017 CODEN: RSUSB

    Citationsformater

    Møller, S. G., Rajan, S., Folke, F., Malta Hansen, C., Hansen, S. M., Kragholm, K., Lippert, F. K., Karlsson, L., Køber, L., Torp-Pedersen, C., Gislason, G. H., & Wissenberg, M. (2016). Temporal trends in survival after out-of-hospital cardiac arrest in patients with and without underlying chronic obstructive pulmonary disease. Resuscitation, 104, 76-82. https://doi.org/10.1016/j.resuscitation.2016.04.017