Symptoms of depression in young adulthood is associated with unfavorable clinical- and behavioral cardiovascular disease risk factors

Heidi Klakk*, Peter Lund Kristensen, Lars Bo Andersen, Karsten Froberg, Niels Christian Møller, Anders Grøntved

*Kontaktforfatter for dette arbejde

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Resumé

Depression in young adults is a growing concern to public health. This study aims to investigate if depression status in young adults is related to clinical and behavioral cardiovascular disease (CVD) risk factors. Cross-sectional data from a population-based sample of young Danish adults participating in the European Youth Heart Study 2009–2010 were used to examine this (n = 644, mean age 24.3 years 47% male). Measures of cardiorespiratory fitness (CRF), body composition, blood pressure, fasting levels of high and low density lipids (HDL, LDL), insulin, and glucose were obtained. Symptoms of depression were obtained using the Major Depression Inventory scale. Information on sleep disorders; drinking and smoking habits were obtained by questionnaires. Associations of depression with CVD risk factors were examined using logistic and linear regression adjusted for age and sex. Prevalence of mild-moderate-severe depression was 8.7% (5.6% males, 11.5% females). Significant sex differences were found in the association between several CVD risk factors and depression status. Women with depression had higher odds of overweight (OR = 2.2, 95%CI: 1.01–4.0), abdominal adiposity (OR = 2.5, 95%CI: 1.2–4.8), low CRF (OR = 2.5, 95%CI: 1.2–5.5), insulin resistance (OR = 2.3, 95%CI: 1.1–4.6), low HDL (OR = 2.0, 95%CI: 1.01–4.1) and high LDL (OR = 2.2, 95%CI: 1.04–4.5) compared to women without depression. Men with depression had significantly increased odds of having high blood pressure and being smokers compared to men without depression (OR: 3.1, 95%CI: 1.1–8.8 and OR: 3.0, 95%CI: 1.1–8.4, respectively). Depression symptoms in young adulthood were related to unfavorable clinical- and behavioral CVD risk factors, particularly in women.

OriginalsprogEngelsk
TidsskriftPreventive Medicine Reports
Vol/bind11
Sider (fra-til)209-215
ISSN2211-3355
DOI
StatusUdgivet - sep. 2018

Fingeraftryk

Depression
Young Adult
Adiposity
Sex Characteristics
Drinking
Habits
Insulin Resistance
Linear Models
Fasting
Public Health
Logistic Models
Smoking
Insulin
Lipids
Equipment and Supplies
Population

Citer dette

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title = "Symptoms of depression in young adulthood is associated with unfavorable clinical- and behavioral cardiovascular disease risk factors",
abstract = "Depression in young adults is a growing concern to public health. This study aims to investigate if depression status in young adults is related to clinical and behavioral cardiovascular disease (CVD) risk factors. Cross-sectional data from a population-based sample of young Danish adults participating in the European Youth Heart Study 2009–2010 were used to examine this (n = 644, mean age 24.3 years 47{\%} male). Measures of cardiorespiratory fitness (CRF), body composition, blood pressure, fasting levels of high and low density lipids (HDL, LDL), insulin, and glucose were obtained. Symptoms of depression were obtained using the Major Depression Inventory scale. Information on sleep disorders; drinking and smoking habits were obtained by questionnaires. Associations of depression with CVD risk factors were examined using logistic and linear regression adjusted for age and sex. Prevalence of mild-moderate-severe depression was 8.7{\%} (5.6{\%} males, 11.5{\%} females). Significant sex differences were found in the association between several CVD risk factors and depression status. Women with depression had higher odds of overweight (OR = 2.2, 95{\%}CI: 1.01–4.0), abdominal adiposity (OR = 2.5, 95{\%}CI: 1.2–4.8), low CRF (OR = 2.5, 95{\%}CI: 1.2–5.5), insulin resistance (OR = 2.3, 95{\%}CI: 1.1–4.6), low HDL (OR = 2.0, 95{\%}CI: 1.01–4.1) and high LDL (OR = 2.2, 95{\%}CI: 1.04–4.5) compared to women without depression. Men with depression had significantly increased odds of having high blood pressure and being smokers compared to men without depression (OR: 3.1, 95{\%}CI: 1.1–8.8 and OR: 3.0, 95{\%}CI: 1.1–8.4, respectively). Depression symptoms in young adulthood were related to unfavorable clinical- and behavioral CVD risk factors, particularly in women.",
keywords = "Behavioral risk, Cardiovascular disease risk, Depression, EYHS, Gender, Young adults",
author = "Heidi Klakk and Kristensen, {Peter Lund} and Andersen, {Lars Bo} and Karsten Froberg and M{\o}ller, {Niels Christian} and Anders Gr{\o}ntved",
year = "2018",
month = "9",
doi = "10.1016/j.pmedr.2018.05.017",
language = "English",
volume = "11",
pages = "209--215",
journal = "Preventive Medicine Reports",
issn = "2211-3355",
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T1 - Symptoms of depression in young adulthood is associated with unfavorable clinical- and behavioral cardiovascular disease risk factors

AU - Klakk, Heidi

AU - Kristensen, Peter Lund

AU - Andersen, Lars Bo

AU - Froberg, Karsten

AU - Møller, Niels Christian

AU - Grøntved, Anders

PY - 2018/9

Y1 - 2018/9

N2 - Depression in young adults is a growing concern to public health. This study aims to investigate if depression status in young adults is related to clinical and behavioral cardiovascular disease (CVD) risk factors. Cross-sectional data from a population-based sample of young Danish adults participating in the European Youth Heart Study 2009–2010 were used to examine this (n = 644, mean age 24.3 years 47% male). Measures of cardiorespiratory fitness (CRF), body composition, blood pressure, fasting levels of high and low density lipids (HDL, LDL), insulin, and glucose were obtained. Symptoms of depression were obtained using the Major Depression Inventory scale. Information on sleep disorders; drinking and smoking habits were obtained by questionnaires. Associations of depression with CVD risk factors were examined using logistic and linear regression adjusted for age and sex. Prevalence of mild-moderate-severe depression was 8.7% (5.6% males, 11.5% females). Significant sex differences were found in the association between several CVD risk factors and depression status. Women with depression had higher odds of overweight (OR = 2.2, 95%CI: 1.01–4.0), abdominal adiposity (OR = 2.5, 95%CI: 1.2–4.8), low CRF (OR = 2.5, 95%CI: 1.2–5.5), insulin resistance (OR = 2.3, 95%CI: 1.1–4.6), low HDL (OR = 2.0, 95%CI: 1.01–4.1) and high LDL (OR = 2.2, 95%CI: 1.04–4.5) compared to women without depression. Men with depression had significantly increased odds of having high blood pressure and being smokers compared to men without depression (OR: 3.1, 95%CI: 1.1–8.8 and OR: 3.0, 95%CI: 1.1–8.4, respectively). Depression symptoms in young adulthood were related to unfavorable clinical- and behavioral CVD risk factors, particularly in women.

AB - Depression in young adults is a growing concern to public health. This study aims to investigate if depression status in young adults is related to clinical and behavioral cardiovascular disease (CVD) risk factors. Cross-sectional data from a population-based sample of young Danish adults participating in the European Youth Heart Study 2009–2010 were used to examine this (n = 644, mean age 24.3 years 47% male). Measures of cardiorespiratory fitness (CRF), body composition, blood pressure, fasting levels of high and low density lipids (HDL, LDL), insulin, and glucose were obtained. Symptoms of depression were obtained using the Major Depression Inventory scale. Information on sleep disorders; drinking and smoking habits were obtained by questionnaires. Associations of depression with CVD risk factors were examined using logistic and linear regression adjusted for age and sex. Prevalence of mild-moderate-severe depression was 8.7% (5.6% males, 11.5% females). Significant sex differences were found in the association between several CVD risk factors and depression status. Women with depression had higher odds of overweight (OR = 2.2, 95%CI: 1.01–4.0), abdominal adiposity (OR = 2.5, 95%CI: 1.2–4.8), low CRF (OR = 2.5, 95%CI: 1.2–5.5), insulin resistance (OR = 2.3, 95%CI: 1.1–4.6), low HDL (OR = 2.0, 95%CI: 1.01–4.1) and high LDL (OR = 2.2, 95%CI: 1.04–4.5) compared to women without depression. Men with depression had significantly increased odds of having high blood pressure and being smokers compared to men without depression (OR: 3.1, 95%CI: 1.1–8.8 and OR: 3.0, 95%CI: 1.1–8.4, respectively). Depression symptoms in young adulthood were related to unfavorable clinical- and behavioral CVD risk factors, particularly in women.

KW - Behavioral risk

KW - Cardiovascular disease risk

KW - Depression

KW - EYHS

KW - Gender

KW - Young adults

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U2 - 10.1016/j.pmedr.2018.05.017

DO - 10.1016/j.pmedr.2018.05.017

M3 - Journal article

VL - 11

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JO - Preventive Medicine Reports

JF - Preventive Medicine Reports

SN - 2211-3355

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