Surveillance of vancomycin-resistant enterococci reveals shift in dominating clones and national spread of a vancomycin-variable vanA Enterococcus faecium ST1421-CT1134 clone, Denmark, 2015 to March 2019

Anette M. Hammerum, Ulrik S. Justesen, Mette Pinholt, Louise Roer, Hülya Kaya, Peder Worning, Sanne Nygaard, Michael Kemp, Marianne Engell Clausen, Karen Leth Nielsen, Jurgita Samulioniené, Mona Kjærsgaard, Claus Østergaard, John Coia, Turid Snekloth Søndergaard, Shahin Gaini, Kristian Schønning, Henrik Westh, Henrik Hasman, Barbara Juliane Holzknecht

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We describe clonal shifts in vanA Enterococcus faecium isolates from clinical samples obtained from patients in Denmark from 2015 to the first quarter (Q1) of 2019. During Q1 2019, the vancomycin-variable enterococci (VVE) ST1421-CT1134 vanA E. faecium became the most dominant vanA E. faecium clone and has spread to all five regions in Denmark. Among 174 E. faecium isolates with vanA, vanB or vanA/vanB genes in Q1 2019, 44% belonged to this type. We describe the clonal shift for vanA Enterococcus faecium during the last 4 years and the national spread of a vancomycin-variable vanA E. faecium ST1421-CT1134 clone in Denmark. The aim is to highlight the importance of using molecular methods for detecting vancomycin-variable enterococci (VVE), and to alert other countries about this emerging nosocomial clone.

OriginalsprogEngelsk
Artikelnummer1900503
TidsskriftEurosurveillance
Vol/bind24
Udgave nummer34
Antal sider5
ISSN1025-496X
DOI
StatusUdgivet - 22. aug. 2019

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