Surveillance of vancomycin-resistant enterococci reveals shift in dominating clones and national spread of a vancomycin-variable vanA Enterococcus faecium ST1421-CT1134 clone, Denmark, 2015 to March 2019

Anette M. Hammerum, Ulrik S. Justesen, Mette Pinholt, Louise Roer, Hülya Kaya, Peder Worning, Sanne Nygaard, Michael Kemp, Marianne Engell Clausen, Karen Leth Nielsen, Jurgita Samulioniené, Mona Kjærsgaard, Claus Østergaard, John Coia, Turid Snekloth Søndergaard, Shahin Gaini, Kristian Schønning, Henrik Westh, Henrik Hasman, Barbara Juliane Holzknecht

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Resumé

We describe clonal shifts in vanA Enterococcus faecium isolates from clinical samples obtained from patients in Denmark from 2015 to the first quarter (Q1) of 2019. During Q1 2019, the vancomycin-variable enterococci (VVE) ST1421-CT1134 vanA E. faecium became the most dominant vanA E. faecium clone and has spread to all five regions in Denmark. Among 174 E. faecium isolates with vanA, vanB or vanA/vanB genes in Q1 2019, 44% belonged to this type.

OriginalsprogEngelsk
Artikelnummer1900503
TidsskriftEurosurveillance
Vol/bind24
Udgave nummer34
Antal sider5
ISSN1025-496X
DOI
StatusUdgivet - 1. aug. 2019

Fingeraftryk

Enterococcus faecium
Denmark
Vancomycin
Clone Cells
Vancomycin-Resistant Enterococci

Citer dette

Hammerum, Anette M. ; Justesen, Ulrik S. ; Pinholt, Mette ; Roer, Louise ; Kaya, Hülya ; Worning, Peder ; Nygaard, Sanne ; Kemp, Michael ; Clausen, Marianne Engell ; Nielsen, Karen Leth ; Samulioniené, Jurgita ; Kjærsgaard, Mona ; Østergaard, Claus ; Coia, John ; Søndergaard, Turid Snekloth ; Gaini, Shahin ; Schønning, Kristian ; Westh, Henrik ; Hasman, Henrik ; Holzknecht, Barbara Juliane. / Surveillance of vancomycin-resistant enterococci reveals shift in dominating clones and national spread of a vancomycin-variable vanA Enterococcus faecium ST1421-CT1134 clone, Denmark, 2015 to March 2019. I: Eurosurveillance. 2019 ; Bind 24, Nr. 34.
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title = "Surveillance of vancomycin-resistant enterococci reveals shift in dominating clones and national spread of a vancomycin-variable vanA Enterococcus faecium ST1421-CT1134 clone, Denmark, 2015 to March 2019",
abstract = "We describe clonal shifts in vanA Enterococcus faecium isolates from clinical samples obtained from patients in Denmark from 2015 to the first quarter (Q1) of 2019. During Q1 2019, the vancomycin-variable enterococci (VVE) ST1421-CT1134 vanA E. faecium became the most dominant vanA E. faecium clone and has spread to all five regions in Denmark. Among 174 E. faecium isolates with vanA, vanB or vanA/vanB genes in Q1 2019, 44{\%} belonged to this type.",
keywords = "Enterococci, MLST, vanA, vanB, VRE, VVE",
author = "Hammerum, {Anette M.} and Justesen, {Ulrik S.} and Mette Pinholt and Louise Roer and H{\"u}lya Kaya and Peder Worning and Sanne Nygaard and Michael Kemp and Clausen, {Marianne Engell} and Nielsen, {Karen Leth} and Jurgita Samulionien{\'e} and Mona Kj{\ae}rsgaard and Claus {\O}stergaard and John Coia and S{\o}ndergaard, {Turid Snekloth} and Shahin Gaini and Kristian Sch{\o}nning and Henrik Westh and Henrik Hasman and Holzknecht, {Barbara Juliane}",
year = "2019",
month = "8",
day = "1",
doi = "10.2807/1560-7917.ES.2019.24.34.1900503",
language = "English",
volume = "24",
journal = "Eurosurveillance",
issn = "1025-496X",
publisher = "Centre Europeen pour la Surveillance Epidemiologique du SIDA",
number = "34",

}

Hammerum, AM, Justesen, US, Pinholt, M, Roer, L, Kaya, H, Worning, P, Nygaard, S, Kemp, M, Clausen, ME, Nielsen, KL, Samulioniené, J, Kjærsgaard, M, Østergaard, C, Coia, J, Søndergaard, TS, Gaini, S, Schønning, K, Westh, H, Hasman, H & Holzknecht, BJ 2019, 'Surveillance of vancomycin-resistant enterococci reveals shift in dominating clones and national spread of a vancomycin-variable vanA Enterococcus faecium ST1421-CT1134 clone, Denmark, 2015 to March 2019', Eurosurveillance, bind 24, nr. 34, 1900503. https://doi.org/10.2807/1560-7917.ES.2019.24.34.1900503

Surveillance of vancomycin-resistant enterococci reveals shift in dominating clones and national spread of a vancomycin-variable vanA Enterococcus faecium ST1421-CT1134 clone, Denmark, 2015 to March 2019. / Hammerum, Anette M.; Justesen, Ulrik S.; Pinholt, Mette; Roer, Louise; Kaya, Hülya; Worning, Peder; Nygaard, Sanne; Kemp, Michael; Clausen, Marianne Engell; Nielsen, Karen Leth; Samulioniené, Jurgita; Kjærsgaard, Mona; Østergaard, Claus; Coia, John; Søndergaard, Turid Snekloth; Gaini, Shahin; Schønning, Kristian; Westh, Henrik; Hasman, Henrik; Holzknecht, Barbara Juliane.

I: Eurosurveillance, Bind 24, Nr. 34, 1900503, 01.08.2019.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

TY - JOUR

T1 - Surveillance of vancomycin-resistant enterococci reveals shift in dominating clones and national spread of a vancomycin-variable vanA Enterococcus faecium ST1421-CT1134 clone, Denmark, 2015 to March 2019

AU - Hammerum, Anette M.

AU - Justesen, Ulrik S.

AU - Pinholt, Mette

AU - Roer, Louise

AU - Kaya, Hülya

AU - Worning, Peder

AU - Nygaard, Sanne

AU - Kemp, Michael

AU - Clausen, Marianne Engell

AU - Nielsen, Karen Leth

AU - Samulioniené, Jurgita

AU - Kjærsgaard, Mona

AU - Østergaard, Claus

AU - Coia, John

AU - Søndergaard, Turid Snekloth

AU - Gaini, Shahin

AU - Schønning, Kristian

AU - Westh, Henrik

AU - Hasman, Henrik

AU - Holzknecht, Barbara Juliane

PY - 2019/8/1

Y1 - 2019/8/1

N2 - We describe clonal shifts in vanA Enterococcus faecium isolates from clinical samples obtained from patients in Denmark from 2015 to the first quarter (Q1) of 2019. During Q1 2019, the vancomycin-variable enterococci (VVE) ST1421-CT1134 vanA E. faecium became the most dominant vanA E. faecium clone and has spread to all five regions in Denmark. Among 174 E. faecium isolates with vanA, vanB or vanA/vanB genes in Q1 2019, 44% belonged to this type.

AB - We describe clonal shifts in vanA Enterococcus faecium isolates from clinical samples obtained from patients in Denmark from 2015 to the first quarter (Q1) of 2019. During Q1 2019, the vancomycin-variable enterococci (VVE) ST1421-CT1134 vanA E. faecium became the most dominant vanA E. faecium clone and has spread to all five regions in Denmark. Among 174 E. faecium isolates with vanA, vanB or vanA/vanB genes in Q1 2019, 44% belonged to this type.

KW - Enterococci

KW - MLST

KW - vanA

KW - vanB

KW - VRE

KW - VVE

U2 - 10.2807/1560-7917.ES.2019.24.34.1900503

DO - 10.2807/1560-7917.ES.2019.24.34.1900503

M3 - Journal article

C2 - 31456560

AN - SCOPUS:85071651705

VL - 24

JO - Eurosurveillance

JF - Eurosurveillance

SN - 1025-496X

IS - 34

M1 - 1900503

ER -