Suchtpotenzial und andere Risiken von Benzodiazepinen und Z-Drugs im Alter

Dirk K. Wolter*

*Kontaktforfatter for dette arbejde

Publikation: Bidrag til tidsskriftReviewForskningpeer review

Resumé

Objective: To review dependence liability and other adverse effects of benzodiazepines (BZD) and z-drugs as well as the treatment of dependency of these drugs in old age. Methods: The author employed a narrative review and did a literature search in PubMed (terms: benzodiazepinz.ast;, z-drugs, zolpidem, zopiclonz.ast;, for each term AND old and elderly, respectively) as well as in more recent relevant textbooks. Selection was made with respect to salience from a geriatric viewpoint and topicality. Results: Use of BZD remains common in old age. Z-drugs, however, have now largely replaced BZD hypnotics. Besides low-dose dependency, both are suspected of causing several health problems including dementia. Z-drugs do not represent a fundamental step forward over BZD: Withdrawal is possible even in old age, but thorough preparation thereof is mandatory. Conclusions: BZD and z-drugs are still important issues in geriatrics.

OriginalsprogTysk
TidsskriftSucht
Vol/bind63
Udgave nummer2
Sider (fra-til)81-97
ISSN0939-5911
DOI
StatusUdgivet - 2017

Fingeraftryk

Pharmaceutical Preparations
Geriatrics
Hypnotics and Sedatives
PubMed
Health
Dependency (Psychology)
zolpidem

Emneord

  • Adverse effects
  • Dementia
  • Low-dose dependency
  • Management
  • Withdrawal

Citer dette

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Suchtpotenzial und andere Risiken von Benzodiazepinen und Z-Drugs im Alter. / Wolter, Dirk K.

I: Sucht, Bind 63, Nr. 2, 2017, s. 81-97.

Publikation: Bidrag til tidsskriftReviewForskningpeer review

TY - JOUR

T1 - Suchtpotenzial und andere Risiken von Benzodiazepinen und Z-Drugs im Alter

AU - Wolter, Dirk K.

PY - 2017

Y1 - 2017

N2 - Objective: To review dependence liability and other adverse effects of benzodiazepines (BZD) and z-drugs as well as the treatment of dependency of these drugs in old age. Methods: The author employed a narrative review and did a literature search in PubMed (terms: benzodiazepinz.ast;, z-drugs, zolpidem, zopiclonz.ast;, for each term AND old and elderly, respectively) as well as in more recent relevant textbooks. Selection was made with respect to salience from a geriatric viewpoint and topicality. Results: Use of BZD remains common in old age. Z-drugs, however, have now largely replaced BZD hypnotics. Besides low-dose dependency, both are suspected of causing several health problems including dementia. Z-drugs do not represent a fundamental step forward over BZD: Withdrawal is possible even in old age, but thorough preparation thereof is mandatory. Conclusions: BZD and z-drugs are still important issues in geriatrics.

AB - Objective: To review dependence liability and other adverse effects of benzodiazepines (BZD) and z-drugs as well as the treatment of dependency of these drugs in old age. Methods: The author employed a narrative review and did a literature search in PubMed (terms: benzodiazepinz.ast;, z-drugs, zolpidem, zopiclonz.ast;, for each term AND old and elderly, respectively) as well as in more recent relevant textbooks. Selection was made with respect to salience from a geriatric viewpoint and topicality. Results: Use of BZD remains common in old age. Z-drugs, however, have now largely replaced BZD hypnotics. Besides low-dose dependency, both are suspected of causing several health problems including dementia. Z-drugs do not represent a fundamental step forward over BZD: Withdrawal is possible even in old age, but thorough preparation thereof is mandatory. Conclusions: BZD and z-drugs are still important issues in geriatrics.

KW - Adverse effects

KW - Dementia

KW - Low-dose dependency

KW - Management

KW - Withdrawal

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