Subjective memory complaints and future depression in primary care patients: A four-year follow-up study

Anna Sophie Quaade, Annette Sofie Davidsen, Volkert Siersma, Gunhild Waldemar, Frans Boch Waldorff

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

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Resumé

OBJECTIVE: To investigate the predictive value of subjective memory complaints (SMCs) for having a hospital-based diagnosis of a single depressive episode over a four-year follow-up period.

METHODS: A prospective register-based cohort study in general practice. All 17 practices in Inner city Copenhagen participated in the study. They had 40,865 registered patients, 2934 aged 65 years or older. Information on SMCs and socio-demographics was collected during two months at enrolment in primary care. Diagnoses of single depressive episodes were retrieved from the Danish Psychiatric Central Research Register. Cox proportional hazard regression models were used to examine risk factors for a hospital-based diagnosis of a single depressive episode.

RESULTS: 758 patients aged 65 years or older consulted their GP in October and November 2002. According to our definition, 177 (23%) had SMCs at enrolment, 12 (6.9%) of whom received a diagnosis of a single depressive episode within the follow-up period. In three multivariate models, SMCs were significantly associated with single depressive episodes. In the fully controlled model SMCs had a hazard ratio (HR) of 2.59 for receiving a subsequent depression diagnosis.

CONCLUSIONS: In an older general practice population, SMCs are associated with increased risk of receiving a hospital-based diagnosis of a single depressive episode.

OriginalsprogEngelsk
TidsskriftGeneral Hospital Psychiatry
Vol/bind55
Sider (fra-til)4-9
ISSN0163-8343
DOI
StatusUdgivet - 4. sep. 2018

Fingeraftryk

Primary Health Care
Depression
General Practice
Proportional Hazards Models
Cohort Studies
Research
Population

Citer dette

Quaade, Anna Sophie ; Davidsen, Annette Sofie ; Siersma, Volkert ; Waldemar, Gunhild ; Waldorff, Frans Boch. / Subjective memory complaints and future depression in primary care patients : A four-year follow-up study. I: General Hospital Psychiatry. 2018 ; Bind 55. s. 4-9.
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title = "Subjective memory complaints and future depression in primary care patients: A four-year follow-up study",
abstract = "OBJECTIVE: To investigate the predictive value of subjective memory complaints (SMCs) for having a hospital-based diagnosis of a single depressive episode over a four-year follow-up period.METHODS: A prospective register-based cohort study in general practice. All 17 practices in Inner city Copenhagen participated in the study. They had 40,865 registered patients, 2934 aged 65 years or older. Information on SMCs and socio-demographics was collected during two months at enrolment in primary care. Diagnoses of single depressive episodes were retrieved from the Danish Psychiatric Central Research Register. Cox proportional hazard regression models were used to examine risk factors for a hospital-based diagnosis of a single depressive episode.RESULTS: 758 patients aged 65 years or older consulted their GP in October and November 2002. According to our definition, 177 (23{\%}) had SMCs at enrolment, 12 (6.9{\%}) of whom received a diagnosis of a single depressive episode within the follow-up period. In three multivariate models, SMCs were significantly associated with single depressive episodes. In the fully controlled model SMCs had a hazard ratio (HR) of 2.59 for receiving a subsequent depression diagnosis.CONCLUSIONS: In an older general practice population, SMCs are associated with increased risk of receiving a hospital-based diagnosis of a single depressive episode.",
keywords = "Depression, Epidemiology, Family practice, Memory complaints, Memory impairment, Single depressive episode",
author = "Quaade, {Anna Sophie} and Davidsen, {Annette Sofie} and Volkert Siersma and Gunhild Waldemar and Waldorff, {Frans Boch}",
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Subjective memory complaints and future depression in primary care patients : A four-year follow-up study. / Quaade, Anna Sophie; Davidsen, Annette Sofie; Siersma, Volkert; Waldemar, Gunhild; Waldorff, Frans Boch.

I: General Hospital Psychiatry, Bind 55, 04.09.2018, s. 4-9.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

TY - JOUR

T1 - Subjective memory complaints and future depression in primary care patients

T2 - A four-year follow-up study

AU - Quaade, Anna Sophie

AU - Davidsen, Annette Sofie

AU - Siersma, Volkert

AU - Waldemar, Gunhild

AU - Waldorff, Frans Boch

N1 - Copyright © 2018 Elsevier Inc. All rights reserved.

PY - 2018/9/4

Y1 - 2018/9/4

N2 - OBJECTIVE: To investigate the predictive value of subjective memory complaints (SMCs) for having a hospital-based diagnosis of a single depressive episode over a four-year follow-up period.METHODS: A prospective register-based cohort study in general practice. All 17 practices in Inner city Copenhagen participated in the study. They had 40,865 registered patients, 2934 aged 65 years or older. Information on SMCs and socio-demographics was collected during two months at enrolment in primary care. Diagnoses of single depressive episodes were retrieved from the Danish Psychiatric Central Research Register. Cox proportional hazard regression models were used to examine risk factors for a hospital-based diagnosis of a single depressive episode.RESULTS: 758 patients aged 65 years or older consulted their GP in October and November 2002. According to our definition, 177 (23%) had SMCs at enrolment, 12 (6.9%) of whom received a diagnosis of a single depressive episode within the follow-up period. In three multivariate models, SMCs were significantly associated with single depressive episodes. In the fully controlled model SMCs had a hazard ratio (HR) of 2.59 for receiving a subsequent depression diagnosis.CONCLUSIONS: In an older general practice population, SMCs are associated with increased risk of receiving a hospital-based diagnosis of a single depressive episode.

AB - OBJECTIVE: To investigate the predictive value of subjective memory complaints (SMCs) for having a hospital-based diagnosis of a single depressive episode over a four-year follow-up period.METHODS: A prospective register-based cohort study in general practice. All 17 practices in Inner city Copenhagen participated in the study. They had 40,865 registered patients, 2934 aged 65 years or older. Information on SMCs and socio-demographics was collected during two months at enrolment in primary care. Diagnoses of single depressive episodes were retrieved from the Danish Psychiatric Central Research Register. Cox proportional hazard regression models were used to examine risk factors for a hospital-based diagnosis of a single depressive episode.RESULTS: 758 patients aged 65 years or older consulted their GP in October and November 2002. According to our definition, 177 (23%) had SMCs at enrolment, 12 (6.9%) of whom received a diagnosis of a single depressive episode within the follow-up period. In three multivariate models, SMCs were significantly associated with single depressive episodes. In the fully controlled model SMCs had a hazard ratio (HR) of 2.59 for receiving a subsequent depression diagnosis.CONCLUSIONS: In an older general practice population, SMCs are associated with increased risk of receiving a hospital-based diagnosis of a single depressive episode.

KW - Depression

KW - Epidemiology

KW - Family practice

KW - Memory complaints

KW - Memory impairment

KW - Single depressive episode

U2 - 10.1016/j.genhosppsych.2018.08.008

DO - 10.1016/j.genhosppsych.2018.08.008

M3 - Journal article

C2 - 30176576

VL - 55

SP - 4

EP - 9

JO - General Hospital Psychiatry

JF - General Hospital Psychiatry

SN - 0163-8343

ER -