Strength training increases the size of the satellite cell pool in type I and II fibres of chronically painful female trapezius muscle

Abigail Louise Mackey, Lars L Andersen, Ulrik Frandsen, Gisela Sjøgaard

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Abstrakt

While strength training has been shown to be effective in mediating hypertrophy and reducing pain in trapezius myalgia, responses at the cellular level have not previously been studied. This study investigated the potential of strength training targeting the affected muscles (SST, n=18) and general fitness training (GFT, n=16) to augment the satellite cell (SC) and macrophage pools in the trapezius muscles of women diagnosed with trapezius myalgia. A group receiving general health information (REF, n=8) served as a control. Muscle biopsies were collected from the trapezius muscles of the 42 women (age 44 ± 8 yrs; mean ± SD) before and after the 10-week intervention period and were analysed by immunohistochemistry for SCs, macrophages, and myonuclei. The SC content of type I and II fibres was observed to increase significantly from baseline by 65% and 164%, respectively, with SST (P
OriginalsprogEngelsk
TidsskriftJournal of Physiology
Vol/bind589
Udgave nummer22
Sider (fra-til)5503–5515
ISSN0022-3751
DOI
StatusUdgivet - jan. 2011

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