Stoppage in Autism Spectrum Disorders

Therese K Grønborg, Stefan N Hansen, Svend V Nielsen, Axel Skytthe, Erik T Parner

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Resumé

Stoppage refers to changes in reproductive behavior following the birth of a child with a severe disease. The presence of stoppage can bias estimates of sibling recurrence risk if not properly addressed. If stoppage occurs non-randomly (differential stoppage), it is possibly an additional source of bias in sibling recurrence risk estimation. This study investigated whether stoppage occurs in Danish families with a firstborn child diagnosed with autism spectrum disorders, and if stoppage was differential. We found that stoppage occurs moderately in Danish families affected by autism spectrum disorders, and that stoppage is differential. However, differential stoppage is a minor source of estimation bias in Danish sibling recurrence risk studies of autism spectrum disorders.
OriginalsprogEngelsk
TidsskriftJournal of Autism and Developmental Disorders
Vol/bind45
Udgave nummer11
Sider (fra-til)3509-19
ISSN0162-3257
DOI
StatusUdgivet - nov. 2015

Fingeraftryk

Siblings
Autism Spectrum Disorder

Citer dette

Grønborg, T. K., Hansen, S. N., Nielsen, S. V., Skytthe, A., & Parner, E. T. (2015). Stoppage in Autism Spectrum Disorders. Journal of Autism and Developmental Disorders, 45(11), 3509-19. https://doi.org/10.1007/s10803-015-2497-3
Grønborg, Therese K ; Hansen, Stefan N ; Nielsen, Svend V ; Skytthe, Axel ; Parner, Erik T. / Stoppage in Autism Spectrum Disorders. I: Journal of Autism and Developmental Disorders. 2015 ; Bind 45, Nr. 11. s. 3509-19.
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title = "Stoppage in Autism Spectrum Disorders",
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Grønborg, TK, Hansen, SN, Nielsen, SV, Skytthe, A & Parner, ET 2015, 'Stoppage in Autism Spectrum Disorders', Journal of Autism and Developmental Disorders, bind 45, nr. 11, s. 3509-19. https://doi.org/10.1007/s10803-015-2497-3

Stoppage in Autism Spectrum Disorders. / Grønborg, Therese K; Hansen, Stefan N; Nielsen, Svend V; Skytthe, Axel; Parner, Erik T.

I: Journal of Autism and Developmental Disorders, Bind 45, Nr. 11, 11.2015, s. 3509-19.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

TY - JOUR

T1 - Stoppage in Autism Spectrum Disorders

AU - Grønborg, Therese K

AU - Hansen, Stefan N

AU - Nielsen, Svend V

AU - Skytthe, Axel

AU - Parner, Erik T

PY - 2015/11

Y1 - 2015/11

N2 - Stoppage refers to changes in reproductive behavior following the birth of a child with a severe disease. The presence of stoppage can bias estimates of sibling recurrence risk if not properly addressed. If stoppage occurs non-randomly (differential stoppage), it is possibly an additional source of bias in sibling recurrence risk estimation. This study investigated whether stoppage occurs in Danish families with a firstborn child diagnosed with autism spectrum disorders, and if stoppage was differential. We found that stoppage occurs moderately in Danish families affected by autism spectrum disorders, and that stoppage is differential. However, differential stoppage is a minor source of estimation bias in Danish sibling recurrence risk studies of autism spectrum disorders.

AB - Stoppage refers to changes in reproductive behavior following the birth of a child with a severe disease. The presence of stoppage can bias estimates of sibling recurrence risk if not properly addressed. If stoppage occurs non-randomly (differential stoppage), it is possibly an additional source of bias in sibling recurrence risk estimation. This study investigated whether stoppage occurs in Danish families with a firstborn child diagnosed with autism spectrum disorders, and if stoppage was differential. We found that stoppage occurs moderately in Danish families affected by autism spectrum disorders, and that stoppage is differential. However, differential stoppage is a minor source of estimation bias in Danish sibling recurrence risk studies of autism spectrum disorders.

KW - Autism spectrum disorder

KW - Sibling recurrence risk

KW - Stoppage

U2 - 10.1007/s10803-015-2497-3

DO - 10.1007/s10803-015-2497-3

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JO - Journal of Autism and Developmental Disorders

JF - Journal of Autism and Developmental Disorders

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