Statiner er sikre ved leversygdom og har muligvis en gunstig effekt

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Resumé

The Danish Medicines Agency recommends routine controls of liver enzymes in patients, who are treated with statins in order to prevent liver injury. In this review, much evidence showing that severe drug-induced hepatic injury is very rarely associated with statins is presented. No data support, that routine control of blood liver enzymes will improve prevention or detection of statin-induced liver injury. Furthermore, recent studies show, that statins are safe and may even have beneficial effects in chronic liver disease. In future revision of the Danish Medicines Agency recommendations, these new findings should be taken into consideration.
OriginalsprogDansk
ArtikelnummerV11180794
TidsskriftUgeskrift for Laeger
Vol/bind181
ISSN0041-5782
StatusE-pub ahead of print - 8. jul. 2019

Fingeraftryk

Hydroxymethylglutaryl-CoA Reductase Inhibitors
Liver Diseases
Liver
Wounds and Injuries
Enzymes
Pharmaceutical Preparations

Citer dette

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title = "Statiner er sikre ved leversygdom og har muligvis en gunstig effekt",
abstract = "The Danish Medicines Agency recommends routine controls of liver enzymes in patients, who are treated with statins in order to prevent liver injury. In this review, much evidence showing that severe drug-induced hepatic injury is very rarely associated with statins is presented. No data support, that routine control of blood liver enzymes will improve prevention or detection of statin-induced liver injury. Furthermore, recent studies show, that statins are safe and may even have beneficial effects in chronic liver disease. In future revision of the Danish Medicines Agency recommendations, these new findings should be taken into consideration.",
author = "{Balle Hugger}, Mie and {Bastrup Israelsen}, Mads and {Dalby Hansen}, Camilla and Aleksander Krag",
year = "2019",
month = "7",
day = "8",
language = "Dansk",
volume = "181",
journal = "Ugeskrift for Laeger",
issn = "0041-5782",
publisher = "Almindelige Danske Laegeforening",

}

Statiner er sikre ved leversygdom og har muligvis en gunstig effekt. / Balle Hugger, Mie; Bastrup Israelsen, Mads; Dalby Hansen, Camilla; Krag, Aleksander.

I: Ugeskrift for Laeger, Bind 181, V11180794, 08.07.2019.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

TY - JOUR

T1 - Statiner er sikre ved leversygdom og har muligvis en gunstig effekt

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AU - Bastrup Israelsen, Mads

AU - Dalby Hansen, Camilla

AU - Krag, Aleksander

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N2 - The Danish Medicines Agency recommends routine controls of liver enzymes in patients, who are treated with statins in order to prevent liver injury. In this review, much evidence showing that severe drug-induced hepatic injury is very rarely associated with statins is presented. No data support, that routine control of blood liver enzymes will improve prevention or detection of statin-induced liver injury. Furthermore, recent studies show, that statins are safe and may even have beneficial effects in chronic liver disease. In future revision of the Danish Medicines Agency recommendations, these new findings should be taken into consideration.

AB - The Danish Medicines Agency recommends routine controls of liver enzymes in patients, who are treated with statins in order to prevent liver injury. In this review, much evidence showing that severe drug-induced hepatic injury is very rarely associated with statins is presented. No data support, that routine control of blood liver enzymes will improve prevention or detection of statin-induced liver injury. Furthermore, recent studies show, that statins are safe and may even have beneficial effects in chronic liver disease. In future revision of the Danish Medicines Agency recommendations, these new findings should be taken into consideration.

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VL - 181

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

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