SNPs in microRNA binding sites in 3'-UTRs of RAAS genes influence arterial blood pressure and risk of myocardial infarction

Anne Yaël Nossent, Jakob Liebe Hansen, Carine Doggen, Paul H A Quax, Søren P Sheikh, Frits R Rosendaal

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Resumé

We hypothesized that single nucleotide polymorphisms (SNPs) located in microRNA (miR) binding sites in genes of the renin angiotensin aldosterone system (RAAS) can influence blood pressure and risk of myocardial infarction.
OriginalsprogEngelsk
TidsskriftAmerican Journal of Hypertension (Spanish Edition)
Vol/bind24
Udgave nummer9
Sider (fra-til)999-1006
Antal sider8
ISSN1139-5990
DOI
StatusUdgivet - 2011

Fingeraftryk

Renin-Angiotensin System
MicroRNAs
Single Nucleotide Polymorphism
Arterial Pressure

Citer dette

Nossent, Anne Yaël ; Hansen, Jakob Liebe ; Doggen, Carine ; Quax, Paul H A ; Sheikh, Søren P ; Rosendaal, Frits R. / SNPs in microRNA binding sites in 3'-UTRs of RAAS genes influence arterial blood pressure and risk of myocardial infarction. I: American Journal of Hypertension (Spanish Edition). 2011 ; Bind 24, Nr. 9. s. 999-1006.
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abstract = "We hypothesized that single nucleotide polymorphisms (SNPs) located in microRNA (miR) binding sites in genes of the renin angiotensin aldosterone system (RAAS) can influence blood pressure and risk of myocardial infarction.",
keywords = "3' Untranslated Regions, Binding Sites, Blood Pressure, Factor VIII, Humans, MicroRNAs, Myocardial Infarction, Polymorphism, Single Nucleotide, Receptor, Bradykinin B2, Receptors, Thromboxane A2, Prostaglandin H2, Receptors, Vasopressin, Renin-Angiotensin System, von Willebrand Factor",
author = "Nossent, {Anne Ya{\"e}l} and Hansen, {Jakob Liebe} and Carine Doggen and Quax, {Paul H A} and Sheikh, {S{\o}ren P} and Rosendaal, {Frits R}",
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SNPs in microRNA binding sites in 3'-UTRs of RAAS genes influence arterial blood pressure and risk of myocardial infarction. / Nossent, Anne Yaël; Hansen, Jakob Liebe; Doggen, Carine; Quax, Paul H A; Sheikh, Søren P; Rosendaal, Frits R.

I: American Journal of Hypertension (Spanish Edition), Bind 24, Nr. 9, 2011, s. 999-1006.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

TY - JOUR

T1 - SNPs in microRNA binding sites in 3'-UTRs of RAAS genes influence arterial blood pressure and risk of myocardial infarction

AU - Nossent, Anne Yaël

AU - Hansen, Jakob Liebe

AU - Doggen, Carine

AU - Quax, Paul H A

AU - Sheikh, Søren P

AU - Rosendaal, Frits R

PY - 2011

Y1 - 2011

N2 - We hypothesized that single nucleotide polymorphisms (SNPs) located in microRNA (miR) binding sites in genes of the renin angiotensin aldosterone system (RAAS) can influence blood pressure and risk of myocardial infarction.

AB - We hypothesized that single nucleotide polymorphisms (SNPs) located in microRNA (miR) binding sites in genes of the renin angiotensin aldosterone system (RAAS) can influence blood pressure and risk of myocardial infarction.

KW - 3' Untranslated Regions

KW - Binding Sites

KW - Blood Pressure

KW - Factor VIII

KW - Humans

KW - MicroRNAs

KW - Myocardial Infarction

KW - Polymorphism, Single Nucleotide

KW - Receptor, Bradykinin B2

KW - Receptors, Thromboxane A2, Prostaglandin H2

KW - Receptors, Vasopressin

KW - Renin-Angiotensin System

KW - von Willebrand Factor

U2 - 10.1038/ajh.2011.92

DO - 10.1038/ajh.2011.92

M3 - Journal article

VL - 24

SP - 999

EP - 1006

JO - American Journal of Hypertension (Spanish Edition)

JF - American Journal of Hypertension (Spanish Edition)

SN - 1139-5990

IS - 9

ER -