@article{0de4f630d0a211dbbc51000ea68e967b,
title = "Smooth muscle cells in atherosclerosis originate from the local vessel wall and not circulating progenitor cells in ApoE knockout mice",
abstract = "Recent studies of bone marrow (BM)-transplanted apoE knockout (apoE-/-) mice have concluded that a substantial fraction of smooth muscle cells (SMCs) in atherosclerosis arise from circulating progenitor cells of hematopoietic origin. This pathway, however, remains controversial. In the present study, we reexamined the origin of plaque SMCs in apoE-/- mice by a series of BM transplantations and in a novel model of atherosclerosis induced in surgically transferred arterial segments.",
keywords = "Animals, Apolipoproteins E, Atherosclerosis, Bone Marrow Transplantation, Cell Differentiation, Cell Movement, Cell Proliferation, Disease Models, Animal, Female, Green Fluorescent Proteins, Hematopoietic Stem Cells, Hyperlipidemias, Male, Mice, Mice, Knockout, Microscopy, Fluorescence, Muscle, Smooth, Vascular, Tunica Intima",
author = "Bentzon, {Jacob Fog} and Charlotte Weile and Sondergaard, {Claus S} and Johnny Hindkjaer and Moustapha Kassem and Erling Falk",
year = "2006",
doi = "10.1161/01.ATV.0000247243.48542.9d",
language = "English",
volume = "26",
pages = "2696--2702",
journal = "Arteriosclerosis, Thrombosis, and Vascular Biology",
issn = "1079-5642",
publisher = "Lippincott Williams & Wilkins",
number = "12",
}