Self-reported workplace bullying and subsequent risk of diagnosed mental disorders and psychotropic drug prescriptions: A register-based prospective cohort study of 75,252 participants

Paul Maurice Conway*, Annette Erlangsen, Matias Brødsgaard Grynderup, Thomas Clausen, Jacob Bue Bjørner, Hermann Burr, Laura Francioli, Anne Helene Garde, Åse Marie Hansen, Linda L. Magnusson Hanson, Jonas Kirchheiner-Rasmussen, Tage S. Kristensen, Eva Gemzøe Mikkelsen, Elsebeth Stenager, Sannie Vester Thorsen, Ebbe Villadsen, Annie Høgh, Reiner Ernst Rugulies

*Kontaktforfatter

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Abstract

depressive disorders and mainly based on non-clinical assessments. This study aims to examine the prospective
association of self-reported workplace bullying with different types of register-based hospital-diagnosed mental
disorders and redeemed psychotropic drug prescriptions.
Methods: Using a cohort study design, we examined a pooled dataset of 75,252 participants from 14 questionnaire-based surveys conducted between 2004 and 2014. In the questionnaires, workplace bullying was measured by a single item. The questionnaires were linked to Danish registers on hospital-diagnosed mental
disorders and redeemed psychotropic drug prescriptions up to 2016. Data were analysed by multivariate Cox proportional hazard models, including only participants without a history of mental disorders or prescriptions
since 1995.
Results: After adjustment for sex, age, marital and socio-economic status, workplace bullying was associated with
an excess risk of any mental disorder (HR 1.37; 95 % CI: 1.17–1.59) as well as mood disorders and neurotic, stress-related, and somatoform disorders. In stratified analyses, this association were statistically significant only
among women. Workplace bullying was also associated with any psychotropic drug prescription (fully-adjusted
HR 1.43; 95 % CI: 1.35–1.53). This association was observed in both sexes and for all prescriptions, including
anxiolytics, hypnotics and sedatives, antidepressants, and nootropics.
Limitations: Firm conclusions about sex-related differences cannot be drawn. Residual confounding by unmeasured factors such as personality cannot be ruled out
OriginalsprogEngelsk
TidsskriftJournal of Affective Disorders
Vol/bind369
Sider (fra-til)1-7
ISSN0165-0327
DOI
StatusUdgivet - 15. jan. 2025

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