Self-reported health and adverse outcomes among women living with symptoms of angina or unspecific chest pain but no diagnosis of obstructive coronary artery disease: findings from the DenHeart study

Jane Lange Dalsgaard*, Michael Skov Hansen, Lars Thrysoee, Ola Ekholm, Charlotte Brun Thorup, Rikke Mols, Trine Bernholdt Rasmussen, Anne Vinggaard Christensen, Selina Kikkenborg Berg, Andreas Kristian Pedersen, Lisette Okkels Jensen, Christian Backer Mogensen, Britt Borregaard

*Kontaktforfatter

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

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Abstract

AIMS: The objectives were to describe differences in self-reported health at discharge between women diagnosed with angina or unspecific chest pain and investigate the association between self-reported health and adverse outcomes within three years.

METHODS AND RESULTS: Data from a national cohort study were used, including data from the DenHeart survey combined with three years of register-based follow-up. The population included two groups of women with symptoms of angina but no diagnosis of obstructive coronary artery disease at discharge (women with angina and women with unspecific chest pain). Self-reported health measured with validated instruments was combined with register-based follow-up on adverse outcomes (a composite of unplanned cardiac readmissions, revascularisation, or all-cause mortality). Associations between self-reported health and time to first adverse outcomes were investigated with Cox Proportional Hazard Models; reported as hazards ratios (HR) with 95% confidence intervals (CI).In total, 1770 women completed the questionnaire (49%). Women with angina (n = 931) reported significantly worse self-reported health on several outcomes than women with unspecific chest pain (n = 839). Within the three years follow-up, women with angina were more often readmitted (29% vs 23%, p = 0.011) and more underwent revascularisation (10% vs 1%, p < 0.001), whereas mortality rates were similar (4% vs 4%, p = 0.750). Self-reported health (physical and mental) was associated with adverse outcomes between both groups (on most instruments).

CONCLUSION: Women with angina reported significantly worse self-reported health on most instruments compared to women with unspecific chest pain. Adverse outcomes varied between groups, with women diagnosed with angina experiencing more events.

REGISTRATION: ClinicalTrials.gov (NCT01926145).

OriginalsprogEngelsk
TidsskriftEuropean Journal of Cardiovascular Nursing
Vol/bind22
Udgave nummer5
Sider (fra-til)506-515
ISSN1474-5151
DOI
StatusUdgivet - 19. jul. 2023

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© The Author(s) 2022. Published by Oxford University Press on behalf of European Society of Cardiology. All rights reserved. For permissions, please e-mail: [email protected].

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