Self-rated health in patients with mild Alzheimer's disease: baseline data from the Danish Alzheimer Intervention Study

Frans Boch Waldorff, Anni B S Nielsen, Gunhild Waldemar

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Resumé

In both epidemiological studies and in clinical trials the patients' own health perception, self-rated health (SRH), measured by a single question, is frequently used as an overall health assessment. Researchers have been encouraged to examine ways of assessing SRH in cognitively impaired persons, but the validity and the influence on other factors on SRH among cognitively impaired persons remain unknown. This study reports how patients with mild Alzheimer's disease (AD) report SRH and which factors influence SRH. The study was based on baseline data from 321 home living patients with mild AD who participated in the Danish Alzheimer Intervention Study (DAISY). Analysis using the generalized estimating equation (GEE) models revealed that good/excellent SRH among patients with mild AD were associated with longer education, lack of other chronic conditions, higher scores of quality of life (QOL), lower scores of mini mental state examination (MMSE), and loss of insight in own cognitive deficits. The present results indicate that SRH reported by patients with mild AD may differ from SRH among cognitively intact persons. Further research is needed in order to establish the validity and implication of SRH in this group of patients.
OriginalsprogEngelsk
TidsskriftArchives of Gerontology and Geriatrics
Vol/bind50
Udgave nummer1
Sider (fra-til)1-5
Antal sider5
ISSN0167-4943
DOI
StatusUdgivet - 2010
Udgivet eksterntJa

Fingeraftryk

Alzheimer Disease
Health
Self Report
Epidemiologic Studies
Quality of Life
Research Personnel
Clinical Trials
Education
Research

Citer dette

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abstract = "In both epidemiological studies and in clinical trials the patients' own health perception, self-rated health (SRH), measured by a single question, is frequently used as an overall health assessment. Researchers have been encouraged to examine ways of assessing SRH in cognitively impaired persons, but the validity and the influence on other factors on SRH among cognitively impaired persons remain unknown. This study reports how patients with mild Alzheimer's disease (AD) report SRH and which factors influence SRH. The study was based on baseline data from 321 home living patients with mild AD who participated in the Danish Alzheimer Intervention Study (DAISY). Analysis using the generalized estimating equation (GEE) models revealed that good/excellent SRH among patients with mild AD were associated with longer education, lack of other chronic conditions, higher scores of quality of life (QOL), lower scores of mini mental state examination (MMSE), and loss of insight in own cognitive deficits. The present results indicate that SRH reported by patients with mild AD may differ from SRH among cognitively intact persons. Further research is needed in order to establish the validity and implication of SRH in this group of patients.",
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Self-rated health in patients with mild Alzheimer's disease: baseline data from the Danish Alzheimer Intervention Study. / Waldorff, Frans Boch; Nielsen, Anni B S; Waldemar, Gunhild.

I: Archives of Gerontology and Geriatrics, Bind 50, Nr. 1, 2010, s. 1-5.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

TY - JOUR

T1 - Self-rated health in patients with mild Alzheimer's disease: baseline data from the Danish Alzheimer Intervention Study

AU - Waldorff, Frans Boch

AU - Nielsen, Anni B S

AU - Waldemar, Gunhild

PY - 2010

Y1 - 2010

N2 - In both epidemiological studies and in clinical trials the patients' own health perception, self-rated health (SRH), measured by a single question, is frequently used as an overall health assessment. Researchers have been encouraged to examine ways of assessing SRH in cognitively impaired persons, but the validity and the influence on other factors on SRH among cognitively impaired persons remain unknown. This study reports how patients with mild Alzheimer's disease (AD) report SRH and which factors influence SRH. The study was based on baseline data from 321 home living patients with mild AD who participated in the Danish Alzheimer Intervention Study (DAISY). Analysis using the generalized estimating equation (GEE) models revealed that good/excellent SRH among patients with mild AD were associated with longer education, lack of other chronic conditions, higher scores of quality of life (QOL), lower scores of mini mental state examination (MMSE), and loss of insight in own cognitive deficits. The present results indicate that SRH reported by patients with mild AD may differ from SRH among cognitively intact persons. Further research is needed in order to establish the validity and implication of SRH in this group of patients.

AB - In both epidemiological studies and in clinical trials the patients' own health perception, self-rated health (SRH), measured by a single question, is frequently used as an overall health assessment. Researchers have been encouraged to examine ways of assessing SRH in cognitively impaired persons, but the validity and the influence on other factors on SRH among cognitively impaired persons remain unknown. This study reports how patients with mild Alzheimer's disease (AD) report SRH and which factors influence SRH. The study was based on baseline data from 321 home living patients with mild AD who participated in the Danish Alzheimer Intervention Study (DAISY). Analysis using the generalized estimating equation (GEE) models revealed that good/excellent SRH among patients with mild AD were associated with longer education, lack of other chronic conditions, higher scores of quality of life (QOL), lower scores of mini mental state examination (MMSE), and loss of insight in own cognitive deficits. The present results indicate that SRH reported by patients with mild AD may differ from SRH among cognitively intact persons. Further research is needed in order to establish the validity and implication of SRH in this group of patients.

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DO - 10.1016/j.archger.2008.12.010

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JO - Archives of Gerontology and Geriatrics

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