Routine patch testing with the sesquiterpene lactone mix in Europe: a 2-year experience:  A multicentre study of the EECDRG

E Paulsen, Klaus Ejner Andersen, F M Brandão, D P Bruynzeel, G Ducombs, P J Frosch, A Goossens, A Lahti, T Menné, S Shaw, A Tosti, J E Wahlberg, J D Wilkinson, K Wrangsjö

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Resumé

Udgivelsesdato: 1999-Feb
OriginalsprogEngelsk
TidsskriftContact Dermatitis
Vol/bind40
Udgave nummer2
Sider (fra-til)72-6
Antal sider4
ISSN0105-1873
StatusUdgivet - 1999

Fingeraftryk

Lactones
Multicenter Studies
Patch Tests
Perfume
Asteraceae
Irritants
Eczema
Skin Diseases
Forearm
Allergens

Citer dette

Paulsen, E ; Andersen, Klaus Ejner ; Brandão, F M ; Bruynzeel, D P ; Ducombs, G ; Frosch, P J ; Goossens, A ; Lahti, A ; Menné, T ; Shaw, S ; Tosti, A ; Wahlberg, J E ; Wilkinson, J D ; Wrangsjö, K. / Routine patch testing with the sesquiterpene lactone mix in Europe: a 2-year experience :  A multicentre study of the EECDRG. I: Contact Dermatitis. 1999 ; Bind 40, Nr. 2. s. 72-6.
@article{cbf87cc0ba9711dc9626000ea68e967b,
title = "Routine patch testing with the sesquiterpene lactone mix in Europe: a 2-year experience:  A multicentre study of the EECDRG",
abstract = "To test the screening value of the sesquiterpene lactone (SL) mix in Europe today and describe epidemiological and clinical features of Compositae-sensitive patients, the SL mix 0.1{\%} pet. was included in the standard patch test series in 11 European clinics. 10,695 patients were tested, and 106 (1{\%}) had positive reactions, 74{\%} of which were of current or old relevance. The prevalence of positive reactions varied between 0.1 and 2.7{\%} in different centres. The median age of the 66 females was 51.5 years, and 55.2 in the 40 males. The 20 occupationally sensitized had a higher {\%} of males and a median age of 43 years, whereas 7 UV-sensitive patients had a median age of 72 years. Garden plants were the major suspected sensitizers and the clinical patterns were partly, in accordance with plant dermatoses in general, involving hands, forearms and face, and partly widespread eczema in a large proportion of the patients. More than 1/3 were positive to perfume and/or colophony, possibly reflecting cross-reactivity. With only 1 case of active sensitization and no irritant reactions, the SL mix is a safe allergen and the overall prevalence of positive reactions supports its continued use in the standard patch test series.",
keywords = "Adult, Aged, Aged, 80 and over, Asteraceae, Chi-Square Distribution, Dermatitis, Allergic Contact, Dermatitis, Occupational, Europe, Female, Humans, Lactones, Male, Middle Aged, Patch Tests, Sesquiterpenes",
author = "E Paulsen and Andersen, {Klaus Ejner} and Brand{\~a}o, {F M} and Bruynzeel, {D P} and G Ducombs and Frosch, {P J} and A Goossens and A Lahti and T Menn{\'e} and S Shaw and A Tosti and Wahlberg, {J E} and Wilkinson, {J D} and K Wrangsj{\"o}",
year = "1999",
language = "English",
volume = "40",
pages = "72--6",
journal = "Contact Dermatitis",
issn = "0105-1873",
publisher = "Wiley-Blackwell",
number = "2",

}

Paulsen, E, Andersen, KE, Brandão, FM, Bruynzeel, DP, Ducombs, G, Frosch, PJ, Goossens, A, Lahti, A, Menné, T, Shaw, S, Tosti, A, Wahlberg, JE, Wilkinson, JD & Wrangsjö, K 1999, 'Routine patch testing with the sesquiterpene lactone mix in Europe: a 2-year experience:  A multicentre study of the EECDRG', Contact Dermatitis, bind 40, nr. 2, s. 72-6.

Routine patch testing with the sesquiterpene lactone mix in Europe: a 2-year experience :  A multicentre study of the EECDRG. / Paulsen, E; Andersen, Klaus Ejner; Brandão, F M; Bruynzeel, D P; Ducombs, G; Frosch, P J; Goossens, A; Lahti, A; Menné, T; Shaw, S; Tosti, A; Wahlberg, J E; Wilkinson, J D; Wrangsjö, K.

I: Contact Dermatitis, Bind 40, Nr. 2, 1999, s. 72-6.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

TY - JOUR

T1 - Routine patch testing with the sesquiterpene lactone mix in Europe: a 2-year experience

T2 -  A multicentre study of the EECDRG

AU - Paulsen, E

AU - Andersen, Klaus Ejner

AU - Brandão, F M

AU - Bruynzeel, D P

AU - Ducombs, G

AU - Frosch, P J

AU - Goossens, A

AU - Lahti, A

AU - Menné, T

AU - Shaw, S

AU - Tosti, A

AU - Wahlberg, J E

AU - Wilkinson, J D

AU - Wrangsjö, K

PY - 1999

Y1 - 1999

N2 - To test the screening value of the sesquiterpene lactone (SL) mix in Europe today and describe epidemiological and clinical features of Compositae-sensitive patients, the SL mix 0.1% pet. was included in the standard patch test series in 11 European clinics. 10,695 patients were tested, and 106 (1%) had positive reactions, 74% of which were of current or old relevance. The prevalence of positive reactions varied between 0.1 and 2.7% in different centres. The median age of the 66 females was 51.5 years, and 55.2 in the 40 males. The 20 occupationally sensitized had a higher % of males and a median age of 43 years, whereas 7 UV-sensitive patients had a median age of 72 years. Garden plants were the major suspected sensitizers and the clinical patterns were partly, in accordance with plant dermatoses in general, involving hands, forearms and face, and partly widespread eczema in a large proportion of the patients. More than 1/3 were positive to perfume and/or colophony, possibly reflecting cross-reactivity. With only 1 case of active sensitization and no irritant reactions, the SL mix is a safe allergen and the overall prevalence of positive reactions supports its continued use in the standard patch test series.

AB - To test the screening value of the sesquiterpene lactone (SL) mix in Europe today and describe epidemiological and clinical features of Compositae-sensitive patients, the SL mix 0.1% pet. was included in the standard patch test series in 11 European clinics. 10,695 patients were tested, and 106 (1%) had positive reactions, 74% of which were of current or old relevance. The prevalence of positive reactions varied between 0.1 and 2.7% in different centres. The median age of the 66 females was 51.5 years, and 55.2 in the 40 males. The 20 occupationally sensitized had a higher % of males and a median age of 43 years, whereas 7 UV-sensitive patients had a median age of 72 years. Garden plants were the major suspected sensitizers and the clinical patterns were partly, in accordance with plant dermatoses in general, involving hands, forearms and face, and partly widespread eczema in a large proportion of the patients. More than 1/3 were positive to perfume and/or colophony, possibly reflecting cross-reactivity. With only 1 case of active sensitization and no irritant reactions, the SL mix is a safe allergen and the overall prevalence of positive reactions supports its continued use in the standard patch test series.

KW - Adult

KW - Aged

KW - Aged, 80 and over

KW - Asteraceae

KW - Chi-Square Distribution

KW - Dermatitis, Allergic Contact

KW - Dermatitis, Occupational

KW - Europe

KW - Female

KW - Humans

KW - Lactones

KW - Male

KW - Middle Aged

KW - Patch Tests

KW - Sesquiterpenes

M3 - Journal article

C2 - 10048650

VL - 40

SP - 72

EP - 76

JO - Contact Dermatitis

JF - Contact Dermatitis

SN - 0105-1873

IS - 2

ER -