Risk of Inflammatory Bowel Disease following Bacille Calmette-Guérin and Smallpox Vaccination: A Population-based Danish Case-Cohort Study

Anne Marie Villumsen, Tine Jess, Signe Sørup, Henrik Ravn, Erik Sturegård, Christine Stabell Benn, Peter Aaby, Adam Anders Edvin Roth

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Abstrakt

Childhood immunology has been suggested to play a role in development of inflammatory bowel disease (IBD) based on the studies of childhood vaccinations, infections, and treatment with antibiotics. Bacille Calmette-Guérin (BCG) and smallpox vaccinations were gradually phased-out in Denmark for children born between 1965 and 1976, hence allowing the study of subsequent risk of Crohn's disease and ulcerative colitis in a unique prospective design.
OriginalsprogEngelsk
TidsskriftInflammatory Bowel Diseases
Vol/bind19
Udgave nummer8
Sider (fra-til)1717-1724
ISSN1078-0998
DOI
StatusUdgivet - 2013

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