Risk factors for Clostridium difficile infection in the community: a case-control study in patients in general practice, Denmark, 2009-2011

Lillian Marie Søes, H M Holt, B Böttiger, H V Nielsen, V Andreasen, M Kemp, K E P Olsen, S Ethelberg, K Mølbak

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Abstrakt

SUMMARY To identify risk factors for Clostridium difficile infection (CDI) in Danish patients consulting general practice with gastrointestinal symptoms, a prospective matched case-control study was performed; cases (N = 259) had positive cultures for toxigenic C. difficile and controls (N = 455) negative cultures. Data were analysed by conditional logistic regression. In patients aged ⩾2 years (138 cases), hospitalization [odds ratio (OR) 8·4, 95% confidence interval (CI) 3·1-23], consumption of beef (OR 5·5, 95% CI 2·0-15), phenoxymethylpenicillin (OR 15, 95% CI 2·7-82), dicloxacillin (OR 27, 95% CI 3·6-211), and extended spectrum penicillins (OR 9·2, 95% CI 1·9-45) were associated with CDI. In patients aged
OriginalsprogEngelsk
TidsskriftEpidemiology and Infection
Vol/bind142
Udgave nummer7
Sider (fra-til)1437-1448
ISSN0950-2688
DOI
StatusUdgivet - 2014

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