Review and comparison of retinal vessel calibre and geometry software and their application to diabetes, cardiovascular disease, and dementia

Laima Brazionis; Nicola Quinn; Sami Dabbah; Chris D. Ryan; Dennis M. Møller; Hilary Richardson; Anthony C. Keech; Andrzej S. Januszewski; Jakob Grauslund; Malin Lundberg Rasmussen; Tunde Peto; Alicia J. Jenkins

doi:10.1007/s00417-023-06002-7

Review and comparison of retinal vessel calibre and geometry software and their application to diabetes, cardiovascular disease, and dementia

Laima Brazionis, Nicola Quinn, Sami Dabbah, Chris D. Ryan, Dennis M. Møller, Hilary Richardson, Anthony C. Keech, Andrzej S. Januszewski^*, Jakob Grauslund, Malin Lundberg Rasmussen, Tunde Peto, Alicia J. Jenkins

^*Kontaktforfatter

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

Abstract

Developments in retinal imaging technologies have enabled the quantitative evaluation of the retinal vasculature. Changes in retinal calibre and/or geometry have been reported in systemic vascular diseases, including diabetes mellitus (DM), cardiovascular disease (CVD), and more recently in neurodegenerative diseases, such as dementia. Several retinal vessel analysis softwares exist, some being disease-specific, others for a broader context. In the research setting, retinal vasculature analysis using semi-automated software has identified associations between retinal vessel calibre and geometry and the presence of or risk of DM and its chronic complications, and of CVD and dementia, including in the general population. In this article, we review and compare the most widely used semi-automated retinal vessel analysis softwares and their associations with ocular imaging findings in common systemic diseases, including DM and its chronic complications, CVD, and dementia. We also provide original data comparing retinal calibre grading in people with Type 1 DM using two softwares, with good concordance.

Originalsprog	Engelsk
Tidsskrift	Graefe's Archive for Clinical and Experimental Ophthalmology
Vol/bind	261
Udgave nummer	8
Sider (fra-til)	2117-2133
ISSN	0721-832X
DOI	https://doi.org/10.1007/s00417-023-06002-7
Status	Udgivet - aug. 2023

Bibliografisk note

Funding Information:
This study (salary support) was funded by the National Health and Medical Research Council (NHMRC, Australia) Centre of Research Excellence in Diabetic Retinopathy (salary support for LB, CR, HR, NQ), a National Heart Foundation Grant (salary support NQ), a NHMRC Practitioner Fellowship (salary support AJJ), a NHMRC Senior Fellowship Grant (salary support ACK), and a University of Sydney Medical School Foundation grant (to AJJ for salary support of ASJ).

Funding Information:
Authors A. Jenkins, T. Peto, L. Brazionis, and A. Januszewski are investigators on an investigator initiated trial of fenofibrate in adults with diabetic retinopathy (the FAME-1 Eye trial) which is funded by the Australian NHMRC, the Juvenile Diabetes Research Foundation (JDRF) Australia and Abbott (EU). A. Jenkins, L. Brazionis, A. Januszewski, and N. Quinn have published research related to the FIELD trial of fenofibrate in diabetes retinopathy.

Dokumenter og links

10.1007/s00417-023-06002-7

Citationsformater

Brazionis, L., Quinn, N., Dabbah, S., Ryan, C. D., Møller, D. M., Richardson, H., Keech, A. C., Januszewski, A. S., Grauslund, J., Rasmussen, M. L., Peto, T., & Jenkins, A. J. (2023). Review and comparison of retinal vessel calibre and geometry software and their application to diabetes, cardiovascular disease, and dementia. Graefe's Archive for Clinical and Experimental Ophthalmology, 261(8), 2117-2133. https://doi.org/10.1007/s00417-023-06002-7

@article{23aeaabf21b74484a59a2d49f95cafc9,

title = "Review and comparison of retinal vessel calibre and geometry software and their application to diabetes, cardiovascular disease, and dementia",

abstract = "Developments in retinal imaging technologies have enabled the quantitative evaluation of the retinal vasculature. Changes in retinal calibre and/or geometry have been reported in systemic vascular diseases, including diabetes mellitus (DM), cardiovascular disease (CVD), and more recently in neurodegenerative diseases, such as dementia. Several retinal vessel analysis softwares exist, some being disease-specific, others for a broader context. In the research setting, retinal vasculature analysis using semi-automated software has identified associations between retinal vessel calibre and geometry and the presence of or risk of DM and its chronic complications, and of CVD and dementia, including in the general population. In this article, we review and compare the most widely used semi-automated retinal vessel analysis softwares and their associations with ocular imaging findings in common systemic diseases, including DM and its chronic complications, CVD, and dementia. We also provide original data comparing retinal calibre grading in people with Type 1 DM using two softwares, with good concordance.",

keywords = "Cardiovascular disease, Dementia, Diabetes, Diabetic retinopathy, Retinal vessel assessment, Software, Cardiovascular Diseases, Retinal Vessels, Humans, Dementia/complications, Diabetic Retinopathy/complications, Diabetes Mellitus, Type 1/complications",

author = "Laima Brazionis and Nicola Quinn and Sami Dabbah and Ryan, {Chris D.} and M{\o}ller, {Dennis M.} and Hilary Richardson and Keech, {Anthony C.} and Januszewski, {Andrzej S.} and Jakob Grauslund and Rasmussen, {Malin Lundberg} and Tunde Peto and Jenkins, {Alicia J.}",

note = "Funding Information: This study (salary support) was funded by the National Health and Medical Research Council (NHMRC, Australia) Centre of Research Excellence in Diabetic Retinopathy (salary support for LB, CR, HR, NQ), a National Heart Foundation Grant (salary support NQ), a NHMRC Practitioner Fellowship (salary support AJJ), a NHMRC Senior Fellowship Grant (salary support ACK), and a University of Sydney Medical School Foundation grant (to AJJ for salary support of ASJ). Funding Information: Authors A. Jenkins, T. Peto, L. Brazionis, and A. Januszewski are investigators on an investigator initiated trial of fenofibrate in adults with diabetic retinopathy (the FAME-1 Eye trial) which is funded by the Australian NHMRC, the Juvenile Diabetes Research Foundation (JDRF) Australia and Abbott (EU). A. Jenkins, L. Brazionis, A. Januszewski, and N. Quinn have published research related to the FIELD trial of fenofibrate in diabetes retinopathy. ",

year = "2023",

month = aug,

doi = "10.1007/s00417-023-06002-7",

language = "English",

volume = "261",

pages = "2117--2133",

journal = "Graefe's Archive for Clinical and Experimental Ophthalmology",

issn = "0721-832X",

publisher = "Springer Science+Business Media",

number = "8",

}

Brazionis, L, Quinn, N, Dabbah, S, Ryan, CD, Møller, DM, Richardson, H, Keech, AC, Januszewski, AS, Grauslund, J, Rasmussen, ML, Peto, T & Jenkins, AJ 2023, 'Review and comparison of retinal vessel calibre and geometry software and their application to diabetes, cardiovascular disease, and dementia', Graefe's Archive for Clinical and Experimental Ophthalmology, bind 261, nr. 8, s. 2117-2133. https://doi.org/10.1007/s00417-023-06002-7

Review and comparison of retinal vessel calibre and geometry software and their application to diabetes, cardiovascular disease, and dementia. / Brazionis, Laima; Quinn, Nicola; Dabbah, Sami et al.
I: Graefe's Archive for Clinical and Experimental Ophthalmology, Bind 261, Nr. 8, 08.2023, s. 2117-2133.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

TY - JOUR

T1 - Review and comparison of retinal vessel calibre and geometry software and their application to diabetes, cardiovascular disease, and dementia

AU - Brazionis, Laima

AU - Quinn, Nicola

AU - Dabbah, Sami

AU - Ryan, Chris D.

AU - Møller, Dennis M.

AU - Richardson, Hilary

AU - Keech, Anthony C.

AU - Januszewski, Andrzej S.

AU - Grauslund, Jakob

AU - Rasmussen, Malin Lundberg

AU - Peto, Tunde

AU - Jenkins, Alicia J.

N1 - Funding Information: This study (salary support) was funded by the National Health and Medical Research Council (NHMRC, Australia) Centre of Research Excellence in Diabetic Retinopathy (salary support for LB, CR, HR, NQ), a National Heart Foundation Grant (salary support NQ), a NHMRC Practitioner Fellowship (salary support AJJ), a NHMRC Senior Fellowship Grant (salary support ACK), and a University of Sydney Medical School Foundation grant (to AJJ for salary support of ASJ). Funding Information: Authors A. Jenkins, T. Peto, L. Brazionis, and A. Januszewski are investigators on an investigator initiated trial of fenofibrate in adults with diabetic retinopathy (the FAME-1 Eye trial) which is funded by the Australian NHMRC, the Juvenile Diabetes Research Foundation (JDRF) Australia and Abbott (EU). A. Jenkins, L. Brazionis, A. Januszewski, and N. Quinn have published research related to the FIELD trial of fenofibrate in diabetes retinopathy.

PY - 2023/8

Y1 - 2023/8

N2 - Developments in retinal imaging technologies have enabled the quantitative evaluation of the retinal vasculature. Changes in retinal calibre and/or geometry have been reported in systemic vascular diseases, including diabetes mellitus (DM), cardiovascular disease (CVD), and more recently in neurodegenerative diseases, such as dementia. Several retinal vessel analysis softwares exist, some being disease-specific, others for a broader context. In the research setting, retinal vasculature analysis using semi-automated software has identified associations between retinal vessel calibre and geometry and the presence of or risk of DM and its chronic complications, and of CVD and dementia, including in the general population. In this article, we review and compare the most widely used semi-automated retinal vessel analysis softwares and their associations with ocular imaging findings in common systemic diseases, including DM and its chronic complications, CVD, and dementia. We also provide original data comparing retinal calibre grading in people with Type 1 DM using two softwares, with good concordance.

AB - Developments in retinal imaging technologies have enabled the quantitative evaluation of the retinal vasculature. Changes in retinal calibre and/or geometry have been reported in systemic vascular diseases, including diabetes mellitus (DM), cardiovascular disease (CVD), and more recently in neurodegenerative diseases, such as dementia. Several retinal vessel analysis softwares exist, some being disease-specific, others for a broader context. In the research setting, retinal vasculature analysis using semi-automated software has identified associations between retinal vessel calibre and geometry and the presence of or risk of DM and its chronic complications, and of CVD and dementia, including in the general population. In this article, we review and compare the most widely used semi-automated retinal vessel analysis softwares and their associations with ocular imaging findings in common systemic diseases, including DM and its chronic complications, CVD, and dementia. We also provide original data comparing retinal calibre grading in people with Type 1 DM using two softwares, with good concordance.

KW - Cardiovascular disease

KW - Dementia

KW - Diabetes

KW - Diabetic retinopathy

KW - Retinal vessel assessment

KW - Software

KW - Cardiovascular Diseases

KW - Retinal Vessels

KW - Humans

KW - Dementia/complications

KW - Diabetic Retinopathy/complications

KW - Diabetes Mellitus, Type 1/complications

U2 - 10.1007/s00417-023-06002-7

DO - 10.1007/s00417-023-06002-7

M3 - Journal article

C2 - 36801971

AN - SCOPUS:85148336517

SN - 0721-832X

VL - 261

SP - 2117

EP - 2133

JO - Graefe's Archive for Clinical and Experimental Ophthalmology

JF - Graefe's Archive for Clinical and Experimental Ophthalmology

IS - 8

ER -

Review and comparison of retinal vessel calibre and geometry software and their application to diabetes, cardiovascular disease, and dementia

Abstract

Bibliografisk note

Dokumenter og links

Fingeraftryk

Citationsformater