Resistance training and aerobic training improve muscle strength and aerobic capacity in chronic inflammatory demyelinating polyneuropathy

Lars H Markvardsen, Kristian Overgaard, Karen Heje, Søren H Sindrup, Ingelise Christiansen, John Vissing, Henning Andersen

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Resumé

Introduction: We investigated the effects of aerobic and resistance exercise in patients with chronic inflammatory demyelinating polyneuropathy (CIDP). Methods: Eighteen CIDP patients treated with subcutaneous immunoglobulin performed 12 weeks of aerobic exercise and 12 weeks of resistance exercise after a run-in period of 12 weeks without exercise. Three times weekly the participants performed aerobic exercise on an ergometer bike or resistance exercise with unilateral training of knee and elbow flexion/extension. Primary outcomes were maximal oxygen consumption velocity (VO 2-max) and maximal combined isokinetic muscle strength (cIKS) of knee and elbow flexion/extension. Results: VO 2-max and muscle strength were unchanged during run-in (−4.9% ± 10.3%, P = 0.80 and −3.7% ± 10.1%, P = 0.17, respectively). Aerobic exercise increased VO 2-max by 11.0% ± 14.7% (P = 0.02). Resistance exercise resulted in an increase of 13.8% ± 16.0% (P = 0.0004) in cIKS. Discussion: Aerobic exercise training and resistance exercise training improve fitness and strength in CIDP patients. Muscle Nerve 57: 70–76, 2018.

OriginalsprogEngelsk
TidsskriftMuscle & Nerve
Vol/bind57
Udgave nummer1
Sider (fra-til)70–76
ISSN0148-639X
DOI
StatusUdgivet - jan. 2018

Fingeraftryk

Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Resistance Training
Exercise
Elbow
Knee
Oxygen Consumption

Citer dette

Markvardsen, Lars H ; Overgaard, Kristian ; Heje, Karen ; Sindrup, Søren H ; Christiansen, Ingelise ; Vissing, John ; Andersen, Henning. / Resistance training and aerobic training improve muscle strength and aerobic capacity in chronic inflammatory demyelinating polyneuropathy. I: Muscle & Nerve. 2018 ; Bind 57, Nr. 1. s. 70–76.
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abstract = "Introduction: We investigated the effects of aerobic and resistance exercise in patients with chronic inflammatory demyelinating polyneuropathy (CIDP). Methods: Eighteen CIDP patients treated with subcutaneous immunoglobulin performed 12 weeks of aerobic exercise and 12 weeks of resistance exercise after a run-in period of 12 weeks without exercise. Three times weekly the participants performed aerobic exercise on an ergometer bike or resistance exercise with unilateral training of knee and elbow flexion/extension. Primary outcomes were maximal oxygen consumption velocity (VO 2-max) and maximal combined isokinetic muscle strength (cIKS) of knee and elbow flexion/extension. Results: VO 2-max and muscle strength were unchanged during run-in (−4.9{\%} ± 10.3{\%}, P = 0.80 and −3.7{\%} ± 10.1{\%}, P = 0.17, respectively). Aerobic exercise increased VO 2-max by 11.0{\%} ± 14.7{\%} (P = 0.02). Resistance exercise resulted in an increase of 13.8{\%} ± 16.0{\%} (P = 0.0004) in cIKS. Discussion: Aerobic exercise training and resistance exercise training improve fitness and strength in CIDP patients. Muscle Nerve 57: 70–76, 2018.",
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Resistance training and aerobic training improve muscle strength and aerobic capacity in chronic inflammatory demyelinating polyneuropathy. / Markvardsen, Lars H; Overgaard, Kristian; Heje, Karen; Sindrup, Søren H; Christiansen, Ingelise; Vissing, John; Andersen, Henning.

I: Muscle & Nerve, Bind 57, Nr. 1, 01.2018, s. 70–76.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

TY - JOUR

T1 - Resistance training and aerobic training improve muscle strength and aerobic capacity in chronic inflammatory demyelinating polyneuropathy

AU - Markvardsen, Lars H

AU - Overgaard, Kristian

AU - Heje, Karen

AU - Sindrup, Søren H

AU - Christiansen, Ingelise

AU - Vissing, John

AU - Andersen, Henning

N1 - © 2017 Wiley Periodicals, Inc.

PY - 2018/1

Y1 - 2018/1

N2 - Introduction: We investigated the effects of aerobic and resistance exercise in patients with chronic inflammatory demyelinating polyneuropathy (CIDP). Methods: Eighteen CIDP patients treated with subcutaneous immunoglobulin performed 12 weeks of aerobic exercise and 12 weeks of resistance exercise after a run-in period of 12 weeks without exercise. Three times weekly the participants performed aerobic exercise on an ergometer bike or resistance exercise with unilateral training of knee and elbow flexion/extension. Primary outcomes were maximal oxygen consumption velocity (VO 2-max) and maximal combined isokinetic muscle strength (cIKS) of knee and elbow flexion/extension. Results: VO 2-max and muscle strength were unchanged during run-in (−4.9% ± 10.3%, P = 0.80 and −3.7% ± 10.1%, P = 0.17, respectively). Aerobic exercise increased VO 2-max by 11.0% ± 14.7% (P = 0.02). Resistance exercise resulted in an increase of 13.8% ± 16.0% (P = 0.0004) in cIKS. Discussion: Aerobic exercise training and resistance exercise training improve fitness and strength in CIDP patients. Muscle Nerve 57: 70–76, 2018.

AB - Introduction: We investigated the effects of aerobic and resistance exercise in patients with chronic inflammatory demyelinating polyneuropathy (CIDP). Methods: Eighteen CIDP patients treated with subcutaneous immunoglobulin performed 12 weeks of aerobic exercise and 12 weeks of resistance exercise after a run-in period of 12 weeks without exercise. Three times weekly the participants performed aerobic exercise on an ergometer bike or resistance exercise with unilateral training of knee and elbow flexion/extension. Primary outcomes were maximal oxygen consumption velocity (VO 2-max) and maximal combined isokinetic muscle strength (cIKS) of knee and elbow flexion/extension. Results: VO 2-max and muscle strength were unchanged during run-in (−4.9% ± 10.3%, P = 0.80 and −3.7% ± 10.1%, P = 0.17, respectively). Aerobic exercise increased VO 2-max by 11.0% ± 14.7% (P = 0.02). Resistance exercise resulted in an increase of 13.8% ± 16.0% (P = 0.0004) in cIKS. Discussion: Aerobic exercise training and resistance exercise training improve fitness and strength in CIDP patients. Muscle Nerve 57: 70–76, 2018.

KW - Journal Article

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KW - Middle Aged

KW - Male

KW - Treatment Outcome

KW - Anaerobic Threshold

KW - Resistance Training

KW - Oxygen Consumption/physiology

KW - Exercise

KW - Knee/physiopathology

KW - Bicycling

KW - Elbow/physiopathology

KW - Immunization, Passive

KW - Quality of Life

KW - Female

KW - Exercise Therapy/methods

KW - Polyradiculoneuropathy, Chronic Inflammatory Demyelinating/physiopathology

KW - Muscle Strength

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EP - 76

JO - Muscle & Nerve

JF - Muscle & Nerve

SN - 0148-639X

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