On the basis of an experimental investigation , numerical investigation is conducted in this paper on damaged seamless metallic pipelines with metal loss (diameter-to-thickness ratio D/t around 21) through nonlinear finite element method (FEM). Numerical models are developed and validated through test results by using the measured material properties and specimen geometry, capable of predicting the residual ultimate strength of pipes in terms of bending capacity (Mcr) and critical curvature (κcr). By changing the metal loss parameters, i.e. length (lm), width (wm) and depth (dm), a series of numerical simulations are carried out. Results show that the larger the dm or lm is, the less the bending capacity will be. The increase of notch width slightly reduces the pipe strength, presenting a linear tendency. Based on the FEM results, empirical formulas are proposed to predict the residual ultimate strength of metallic pipes with metal loss under pure bending moment. The prediction results match well with the results from the tests, the numerical simulations as well as the theoretical derivation. Such formulas can be therefore used for practice purposes and facilitate the decision-making of pipe maintenance after mechanical interference.