Recommendations for the management of rheumatoid arthritis in the Eastern Mediterranean region: an adolopment of the 2015 American College of Rheumatology guidelines

Thurayya Arayssi*, Manale Harfouche, Andrea Darzi, Samar Al Emadi, Khaled A. Alnaqbi, Humeira Badsha, Farida Al Balushi, Carole Dib, Bassel Elzorkany, Hussein Halabi, Mohammed Hammoudeh, Wissam Hazer, Basel Masri, Mira Merashli, Mohammed Omair, Nelly Salloum, Imad Uthman, Sumeja Zahirovic, Nelly Ziade, Raveendhara R. BannuruTimothy McAlindon, Mohamed A. Nomier, Jasvinder A. Singh, Robin Christensen, Peter Tugwell, Holger Schünemann, Elie A. Akl

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Abstrakt

Clinical practice guidelines can assist rheumatologists in the proper prescription of newer treatment for rheumatoid arthritis (RA). The objective of this paper is to report on the recommendations for the management of patients with RA in the Eastern Mediterranean region. We adapted the 2015 American College of Rheumatology guidelines in two separate waves. We used the adolopment methodology, and followed the 18 steps of the “Guidelines 2.0” comprehensive checklist for guideline development. For each question, we updated the original guidelines’ evidence synthesis, and we developed an Evidence Profile (EP) and an Evidence to Decision (EtD) table. In the first wave, we adoloped eight out of the 15 original questions on early RA. The strength changed for five of these recommendations from strong to conditional, due to one or more of the following factors: cost, impact on health equities, the balance of benefits, and harms and acceptability. In the second wave, we adoloped eight out of the original 44 questions on established RA. The strength changed for two of these recommendations from strong to conditional, in both cases due to cost, impact on health equities, balance of benefits and harms, and acceptability. The panel also developed a good practice recommendation. We successfully adoloped 16 recommendations for the management of early and established RA in the Eastern Mediterranean region. The process proved feasible and sensitive to contextual factors.

OriginalsprogEngelsk
TidsskriftClinical Rheumatology
Vol/bind37
Udgave nummer11
Sider (fra-til)2947–2959
ISSN0770-3198
DOI
StatusUdgivet - nov. 2018

Bibliografisk note

The original version of this article, unfortunately, contained an error. In the original version of this article the first name of the co-author was incorrectly spelled as “Khaled A. Alnaqbi”. The correct spelling should have been “Khalid A. Alnaqbi”. This is now presented correctly in this article. The original article has been corrected.

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