Quantification of colour Doppler activity in the wrist in patients with rheumatoid arthritis - the reliability of different methods for image selection and evaluation

K Ellegaard, S Torp-Pedersen, Hans Lund, M Henriksen, L Terslev, P S Jensen, B Danneskiold-Samsøe, H Bliddal

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Resumé

Udgivelsesdato: 2008-Aug
OriginalsprogEngelsk
TidsskriftUltraschall in der Medizin
Vol/bind29
Udgave nummer4
Sider (fra-til)393-8
Antal sider5
ISSN0172-4614
DOI
StatusUdgivet - 1. aug. 2008
Udgivet eksterntJa

Fingeraftryk

Wrist
Color
Reproducibility of Results
Doppler Ultrasonography
Research Personnel

Citer dette

Ellegaard, K ; Torp-Pedersen, S ; Lund, Hans ; Henriksen, M ; Terslev, L ; Jensen, P S ; Danneskiold-Samsøe, B ; Bliddal, H. / Quantification of colour Doppler activity in the wrist in patients with rheumatoid arthritis - the reliability of different methods for image selection and evaluation. I: Ultraschall in der Medizin. 2008 ; Bind 29, Nr. 4. s. 393-8.
@article{77983f20db1711dd9908000ea68e967b,
title = "Quantification of colour Doppler activity in the wrist in patients with rheumatoid arthritis - the reliability of different methods for image selection and evaluation",
abstract = "PURPOSE: The amount of colour Doppler activity in the inflamed synovium is used to quantify inflammatory activity. The measurements may vary due to image selection, quantification method, and point in cardiac cycle. This study investigated the test-retest reliability of ultrasound colour Doppler measurements in the wrist of patients with rheumatoid arthritis (RA) using different selection and quantification methods. MATERIALS AND METHODS: 14 patients with RA had their wrist scanned twice by the same investigator with an interval of 30 minutes. The images for analysis were selected either by the anatomical position only or by the anatomical position with maximum colour Doppler activity. Subsequently, the amount of colour Doppler was measured in an area defined by either the synovial tissue or by specific anatomical structures surrounding the synovial tissue. RESULTS: The best test-retest reliability was obtained when the images were selected guided by colour Doppler and the subsequent quantification was done in an area defined by anatomical structures. With this method, the intra-class coefficient ICC (2.1) was 0.95 and the within-subject SD (SW) was 0.017, indicating good reliability. In contrast, poor test-retest reliability was found if the images were selected by anatomical position only and the quantification was done in an area defined by the synovial tissue (ICC [2.1] = 0.48 and SW = 0.049). CONCLUSION: The study showed that colour Doppler measurements are reliable if the images for analysis are selected by anatomical position in combination with colour Doppler activity and the subsequent analysis is performed in an area defined by anatomical structures.",
author = "K Ellegaard and S Torp-Pedersen and Hans Lund and M Henriksen and L Terslev and Jensen, {P S} and B Danneskiold-Sams{\o}e and H Bliddal",
year = "2008",
month = "8",
day = "1",
doi = "10.1055/s-2008-1027196",
language = "English",
volume = "29",
pages = "393--8",
journal = "Ultraschall in der Medizin",
issn = "0172-4614",
publisher = "GeorgThieme Verlag",
number = "4",

}

Quantification of colour Doppler activity in the wrist in patients with rheumatoid arthritis - the reliability of different methods for image selection and evaluation. / Ellegaard, K; Torp-Pedersen, S; Lund, Hans; Henriksen, M; Terslev, L; Jensen, P S; Danneskiold-Samsøe, B; Bliddal, H.

I: Ultraschall in der Medizin, Bind 29, Nr. 4, 01.08.2008, s. 393-8.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

TY - JOUR

T1 - Quantification of colour Doppler activity in the wrist in patients with rheumatoid arthritis - the reliability of different methods for image selection and evaluation

AU - Ellegaard, K

AU - Torp-Pedersen, S

AU - Lund, Hans

AU - Henriksen, M

AU - Terslev, L

AU - Jensen, P S

AU - Danneskiold-Samsøe, B

AU - Bliddal, H

PY - 2008/8/1

Y1 - 2008/8/1

N2 - PURPOSE: The amount of colour Doppler activity in the inflamed synovium is used to quantify inflammatory activity. The measurements may vary due to image selection, quantification method, and point in cardiac cycle. This study investigated the test-retest reliability of ultrasound colour Doppler measurements in the wrist of patients with rheumatoid arthritis (RA) using different selection and quantification methods. MATERIALS AND METHODS: 14 patients with RA had their wrist scanned twice by the same investigator with an interval of 30 minutes. The images for analysis were selected either by the anatomical position only or by the anatomical position with maximum colour Doppler activity. Subsequently, the amount of colour Doppler was measured in an area defined by either the synovial tissue or by specific anatomical structures surrounding the synovial tissue. RESULTS: The best test-retest reliability was obtained when the images were selected guided by colour Doppler and the subsequent quantification was done in an area defined by anatomical structures. With this method, the intra-class coefficient ICC (2.1) was 0.95 and the within-subject SD (SW) was 0.017, indicating good reliability. In contrast, poor test-retest reliability was found if the images were selected by anatomical position only and the quantification was done in an area defined by the synovial tissue (ICC [2.1] = 0.48 and SW = 0.049). CONCLUSION: The study showed that colour Doppler measurements are reliable if the images for analysis are selected by anatomical position in combination with colour Doppler activity and the subsequent analysis is performed in an area defined by anatomical structures.

AB - PURPOSE: The amount of colour Doppler activity in the inflamed synovium is used to quantify inflammatory activity. The measurements may vary due to image selection, quantification method, and point in cardiac cycle. This study investigated the test-retest reliability of ultrasound colour Doppler measurements in the wrist of patients with rheumatoid arthritis (RA) using different selection and quantification methods. MATERIALS AND METHODS: 14 patients with RA had their wrist scanned twice by the same investigator with an interval of 30 minutes. The images for analysis were selected either by the anatomical position only or by the anatomical position with maximum colour Doppler activity. Subsequently, the amount of colour Doppler was measured in an area defined by either the synovial tissue or by specific anatomical structures surrounding the synovial tissue. RESULTS: The best test-retest reliability was obtained when the images were selected guided by colour Doppler and the subsequent quantification was done in an area defined by anatomical structures. With this method, the intra-class coefficient ICC (2.1) was 0.95 and the within-subject SD (SW) was 0.017, indicating good reliability. In contrast, poor test-retest reliability was found if the images were selected by anatomical position only and the quantification was done in an area defined by the synovial tissue (ICC [2.1] = 0.48 and SW = 0.049). CONCLUSION: The study showed that colour Doppler measurements are reliable if the images for analysis are selected by anatomical position in combination with colour Doppler activity and the subsequent analysis is performed in an area defined by anatomical structures.

U2 - 10.1055/s-2008-1027196

DO - 10.1055/s-2008-1027196

M3 - Journal article

C2 - 18709606

VL - 29

SP - 393

EP - 398

JO - Ultraschall in der Medizin

JF - Ultraschall in der Medizin

SN - 0172-4614

IS - 4

ER -