Pulmonary and caval flow dynamics after total cavopulmonary connection

K Houlind*, E V Stenbøg, K E Sørensen, K Emmertsen, O K Hansen, L Rybro, V E Hjortdal

*Kontaktforfatter for dette arbejde

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Resumé

OBJECTIVE: To assess flow dynamics after total cavopulmonary connection (TCPC).

DESIGN: Cross-sectional study.

SETTING: Aarhus University Hospital.

PATIENTS: Seven patients (mean age 9 (4-18) years) who had previously undergone a lateral tunnel TCPC mean 2 (0. 3-5) years earlier.

INTERVENTIONS: Pressure recordings (cardiac catheterisation), flow volume, and temporal changes of flow in the lateral tunnel, superior vena cava, and right and left pulmonary arteries (magnetic resonance velocity mapping).

RESULTS: Superior vena cava flow was similar to lateral tunnel flow (1.7 (0.6-1.9) v 1. 3 (0.9-2.4) l/min*m2) (NS), and right pulmonary artery flow was higher than left pulmonary artery flow (1.7 (0.6-4.3) v 1.1 (0.8-2. 5) l/min*m2, p < 0.05). The flow pulsatility index was highest in the lateral tunnel (2.0 (1.1-8.5)), lowest in the superior vena cava (0.8 (0.5-2.4)), and intermediate in the left and right pulmonary arteries (1.6 (0.9-2.0) and 1.2 (0.4-1.9), respectively). Flow and pressure waveforms were biphasic with maxima in atrial systole and late ventricular systole.

CONCLUSIONS: Following a standard lateral tunnel TCPC, flow returning via the superior vena cava is not lower than flow returning via the inferior vena cava as otherwise seen in healthy subjects; flow distribution to the pulmonary arteries is optimal; and some pulsatility is preserved primarily in the lateral tunnel and the corresponding pulmonary artery. This study provides in vivo data for future in vitro and computer model studies.

OriginalsprogEngelsk
TidsskriftHeart
Vol/bind81
Udgave nummer1
Sider (fra-til)67-72
ISSN1355-6037
DOI
StatusUdgivet - jan. 1999
Udgivet eksterntJa

Fingeraftryk

Pulmonary Artery
Superior Vena Cava
Lung
Inferior Vena Cava
Computer Simulation
Cross-Sectional Studies

Citer dette

Houlind, K., Stenbøg, E. V., Sørensen, K. E., Emmertsen, K., Hansen, O. K., Rybro, L., & Hjortdal, V. E. (1999). Pulmonary and caval flow dynamics after total cavopulmonary connection. Heart, 81(1), 67-72. https://doi.org/10.1136/hrt.81.1.67
Houlind, K ; Stenbøg, E V ; Sørensen, K E ; Emmertsen, K ; Hansen, O K ; Rybro, L ; Hjortdal, V E. / Pulmonary and caval flow dynamics after total cavopulmonary connection. I: Heart. 1999 ; Bind 81, Nr. 1. s. 67-72.
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abstract = "OBJECTIVE: To assess flow dynamics after total cavopulmonary connection (TCPC).DESIGN: Cross-sectional study.SETTING: Aarhus University Hospital.PATIENTS: Seven patients (mean age 9 (4-18) years) who had previously undergone a lateral tunnel TCPC mean 2 (0. 3-5) years earlier.INTERVENTIONS: Pressure recordings (cardiac catheterisation), flow volume, and temporal changes of flow in the lateral tunnel, superior vena cava, and right and left pulmonary arteries (magnetic resonance velocity mapping).RESULTS: Superior vena cava flow was similar to lateral tunnel flow (1.7 (0.6-1.9) v 1. 3 (0.9-2.4) l/min*m2) (NS), and right pulmonary artery flow was higher than left pulmonary artery flow (1.7 (0.6-4.3) v 1.1 (0.8-2. 5) l/min*m2, p < 0.05). The flow pulsatility index was highest in the lateral tunnel (2.0 (1.1-8.5)), lowest in the superior vena cava (0.8 (0.5-2.4)), and intermediate in the left and right pulmonary arteries (1.6 (0.9-2.0) and 1.2 (0.4-1.9), respectively). Flow and pressure waveforms were biphasic with maxima in atrial systole and late ventricular systole.CONCLUSIONS: Following a standard lateral tunnel TCPC, flow returning via the superior vena cava is not lower than flow returning via the inferior vena cava as otherwise seen in healthy subjects; flow distribution to the pulmonary arteries is optimal; and some pulsatility is preserved primarily in the lateral tunnel and the corresponding pulmonary artery. This study provides in vivo data for future in vitro and computer model studies.",
keywords = "Adolescent, Cardiac Catheterization, Child, Child, Preschool, Cross-Sectional Studies, Female, Heart Bypass, Right, Heart Defects, Congenital/surgery, Humans, Magnetic Resonance Imaging, Male, Pulmonary Artery, Pulmonary Circulation, Pulsatile Flow, Regional Blood Flow, Signal Processing, Computer-Assisted, Statistics, Nonparametric, Treatment Outcome, Vena Cava, Superior, Venae Cavae",
author = "K Houlind and Stenb{\o}g, {E V} and S{\o}rensen, {K E} and K Emmertsen and Hansen, {O K} and L Rybro and Hjortdal, {V E}",
year = "1999",
month = "1",
doi = "10.1136/hrt.81.1.67",
language = "English",
volume = "81",
pages = "67--72",
journal = "Heart",
issn = "1355-6037",
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Houlind, K, Stenbøg, EV, Sørensen, KE, Emmertsen, K, Hansen, OK, Rybro, L & Hjortdal, VE 1999, 'Pulmonary and caval flow dynamics after total cavopulmonary connection', Heart, bind 81, nr. 1, s. 67-72. https://doi.org/10.1136/hrt.81.1.67

Pulmonary and caval flow dynamics after total cavopulmonary connection. / Houlind, K; Stenbøg, E V; Sørensen, K E; Emmertsen, K; Hansen, O K; Rybro, L; Hjortdal, V E.

I: Heart, Bind 81, Nr. 1, 01.1999, s. 67-72.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

TY - JOUR

T1 - Pulmonary and caval flow dynamics after total cavopulmonary connection

AU - Houlind, K

AU - Stenbøg, E V

AU - Sørensen, K E

AU - Emmertsen, K

AU - Hansen, O K

AU - Rybro, L

AU - Hjortdal, V E

PY - 1999/1

Y1 - 1999/1

N2 - OBJECTIVE: To assess flow dynamics after total cavopulmonary connection (TCPC).DESIGN: Cross-sectional study.SETTING: Aarhus University Hospital.PATIENTS: Seven patients (mean age 9 (4-18) years) who had previously undergone a lateral tunnel TCPC mean 2 (0. 3-5) years earlier.INTERVENTIONS: Pressure recordings (cardiac catheterisation), flow volume, and temporal changes of flow in the lateral tunnel, superior vena cava, and right and left pulmonary arteries (magnetic resonance velocity mapping).RESULTS: Superior vena cava flow was similar to lateral tunnel flow (1.7 (0.6-1.9) v 1. 3 (0.9-2.4) l/min*m2) (NS), and right pulmonary artery flow was higher than left pulmonary artery flow (1.7 (0.6-4.3) v 1.1 (0.8-2. 5) l/min*m2, p < 0.05). The flow pulsatility index was highest in the lateral tunnel (2.0 (1.1-8.5)), lowest in the superior vena cava (0.8 (0.5-2.4)), and intermediate in the left and right pulmonary arteries (1.6 (0.9-2.0) and 1.2 (0.4-1.9), respectively). Flow and pressure waveforms were biphasic with maxima in atrial systole and late ventricular systole.CONCLUSIONS: Following a standard lateral tunnel TCPC, flow returning via the superior vena cava is not lower than flow returning via the inferior vena cava as otherwise seen in healthy subjects; flow distribution to the pulmonary arteries is optimal; and some pulsatility is preserved primarily in the lateral tunnel and the corresponding pulmonary artery. This study provides in vivo data for future in vitro and computer model studies.

AB - OBJECTIVE: To assess flow dynamics after total cavopulmonary connection (TCPC).DESIGN: Cross-sectional study.SETTING: Aarhus University Hospital.PATIENTS: Seven patients (mean age 9 (4-18) years) who had previously undergone a lateral tunnel TCPC mean 2 (0. 3-5) years earlier.INTERVENTIONS: Pressure recordings (cardiac catheterisation), flow volume, and temporal changes of flow in the lateral tunnel, superior vena cava, and right and left pulmonary arteries (magnetic resonance velocity mapping).RESULTS: Superior vena cava flow was similar to lateral tunnel flow (1.7 (0.6-1.9) v 1. 3 (0.9-2.4) l/min*m2) (NS), and right pulmonary artery flow was higher than left pulmonary artery flow (1.7 (0.6-4.3) v 1.1 (0.8-2. 5) l/min*m2, p < 0.05). The flow pulsatility index was highest in the lateral tunnel (2.0 (1.1-8.5)), lowest in the superior vena cava (0.8 (0.5-2.4)), and intermediate in the left and right pulmonary arteries (1.6 (0.9-2.0) and 1.2 (0.4-1.9), respectively). Flow and pressure waveforms were biphasic with maxima in atrial systole and late ventricular systole.CONCLUSIONS: Following a standard lateral tunnel TCPC, flow returning via the superior vena cava is not lower than flow returning via the inferior vena cava as otherwise seen in healthy subjects; flow distribution to the pulmonary arteries is optimal; and some pulsatility is preserved primarily in the lateral tunnel and the corresponding pulmonary artery. This study provides in vivo data for future in vitro and computer model studies.

KW - Adolescent

KW - Cardiac Catheterization

KW - Child

KW - Child, Preschool

KW - Cross-Sectional Studies

KW - Female

KW - Heart Bypass, Right

KW - Heart Defects, Congenital/surgery

KW - Humans

KW - Magnetic Resonance Imaging

KW - Male

KW - Pulmonary Artery

KW - Pulmonary Circulation

KW - Pulsatile Flow

KW - Regional Blood Flow

KW - Signal Processing, Computer-Assisted

KW - Statistics, Nonparametric

KW - Treatment Outcome

KW - Vena Cava, Superior

KW - Venae Cavae

U2 - 10.1136/hrt.81.1.67

DO - 10.1136/hrt.81.1.67

M3 - Journal article

C2 - 10220548

VL - 81

SP - 67

EP - 72

JO - Heart

JF - Heart

SN - 1355-6037

IS - 1

ER -

Houlind K, Stenbøg EV, Sørensen KE, Emmertsen K, Hansen OK, Rybro L et al. Pulmonary and caval flow dynamics after total cavopulmonary connection. Heart. 1999 jan;81(1):67-72. https://doi.org/10.1136/hrt.81.1.67