Production of the Auger emitter 119Sb for targeted radionuclide therapy using a small PET-cyclotron

Helge Thisgaard; M Jensen

doi:10.1016/j.apradiso.2008.09.003

Production of the Auger emitter 119Sb for targeted radionuclide therapy using a small PET-cyclotron

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

Resumé

The use of Auger electrons in radionuclide therapy of cancer is a promising tool for specific tumor cell killing of micrometastases and small tumors. The radioisotope (119)Sb has recently been identified as a potent Auger-emitter for therapy. We here present a method for producing this isotope using a low-energy cyclotron. With this method, it will be possible to produce clinically relevant amounts of (119)Sb radioactivity with high chemical and radionuclidic purity for cancer therapy.

Originalsprog	Engelsk
Tidsskrift	Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine
Vol/bind	67
Udgave nummer	1
Sider (fra-til)	34-8
Antal sider	5
DOI	https://doi.org/10.1016/j.apradiso.2008.09.003
Status	Udgivet - 1. jan. 2009
Udgivet eksternt	Ja

Fingeraftryk

Cyclotrons

Radioisotopes

radioactive isotopes

cyclotrons

Tumors

therapy

emitters

Radioactivity

tumors

cancer

Isotopes

Neoplasms

Cells

radioactivity

Neoplasm Micrometastasis

Electrons

purity

isotopes

electrons

energy

Citer dette

Thisgaard, H., & Jensen, M. (2009). Production of the Auger emitter 119Sb for targeted radionuclide therapy using a small PET-cyclotron. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 67(1), 34-8. https://doi.org/10.1016/j.apradiso.2008.09.003

Thisgaard, Helge ; Jensen, M. / Production of the Auger emitter 119Sb for targeted radionuclide therapy using a small PET-cyclotron. I: Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine. 2009 ; Bind 67, Nr. 1. s. 34-8.

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abstract = "The use of Auger electrons in radionuclide therapy of cancer is a promising tool for specific tumor cell killing of micrometastases and small tumors. The radioisotope (119)Sb has recently been identified as a potent Auger-emitter for therapy. We here present a method for producing this isotope using a low-energy cyclotron. With this method, it will be possible to produce clinically relevant amounts of (119)Sb radioactivity with high chemical and radionuclidic purity for cancer therapy.",

author = "Helge Thisgaard and M Jensen",

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doi = "10.1016/j.apradiso.2008.09.003",

language = "English",

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Thisgaard, H & Jensen, M 2009, 'Production of the Auger emitter 119Sb for targeted radionuclide therapy using a small PET-cyclotron', Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, bind 67, nr. 1, s. 34-8. https://doi.org/10.1016/j.apradiso.2008.09.003

Production of the Auger emitter 119Sb for targeted radionuclide therapy using a small PET-cyclotron. / Thisgaard, Helge; Jensen, M.

I: Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, Bind 67, Nr. 1, 01.01.2009, s. 34-8.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

TY - JOUR

T1 - Production of the Auger emitter 119Sb for targeted radionuclide therapy using a small PET-cyclotron

AU - Thisgaard, Helge

AU - Jensen, M

PY - 2009/1/1

Y1 - 2009/1/1

N2 - The use of Auger electrons in radionuclide therapy of cancer is a promising tool for specific tumor cell killing of micrometastases and small tumors. The radioisotope (119)Sb has recently been identified as a potent Auger-emitter for therapy. We here present a method for producing this isotope using a low-energy cyclotron. With this method, it will be possible to produce clinically relevant amounts of (119)Sb radioactivity with high chemical and radionuclidic purity for cancer therapy.

AB - The use of Auger electrons in radionuclide therapy of cancer is a promising tool for specific tumor cell killing of micrometastases and small tumors. The radioisotope (119)Sb has recently been identified as a potent Auger-emitter for therapy. We here present a method for producing this isotope using a low-energy cyclotron. With this method, it will be possible to produce clinically relevant amounts of (119)Sb radioactivity with high chemical and radionuclidic purity for cancer therapy.

U2 - 10.1016/j.apradiso.2008.09.003

DO - 10.1016/j.apradiso.2008.09.003

M3 - Journal article

VL - 67

SP - 34

EP - 38

JO - Applied Radiation and Isotopes

JF - Applied Radiation and Isotopes

SN - 0969-8043

IS - 1

ER -

Thisgaard H, Jensen M. Production of the Auger emitter 119Sb for targeted radionuclide therapy using a small PET-cyclotron. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine. 2009 jan 1;67(1):34-8. https://doi.org/10.1016/j.apradiso.2008.09.003

Dokumenter og links

10.1016/j.apradiso.2008.09.003