Prevalence of patients with self-reported hidradenitis suppurativa in a cohort of Danish blood donors

a cross-sectional study

P. Theut Riis*, O. B. Pedersen, V. Sigsgaard, C. Erikstrup, H. M. Paarup, K. R. Nielsen, K. S. Burgdorf, H. Hjalgrim, K. Rostgaard, K. Banasik, H. Ullum, G. B. Jemec

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Resumé

Background: Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease characterized by recurrent inflamed nodules. No pathognomonic test is available for HS; hence the diagnosis is based on three clinical criteria. Objectives: To estimate the cross-sectional prevalence and characterize patients with HS in the Danish Blood Donor Study cohort. Methods: A questionnaire previously developed containing HS screening questions, the Major Depression Inventory, the Short Form-12, as well as questions about height, weight and drinking habits was answered by 27 765 blood donors. Results: The prevalence of HS was 1·8% [95% confidence interval (CI) 1·6–2·0%] in the cohort of Danish blood donors. Donors with HS were on average 4·7 years younger (P < 0·001), had 1·3 kg m−2 higher mean body mass index (BMI) (P < 0·001) and were significantly more likely to smoke [odds ratio (OR) 1·44, 17·9% vs. 13·1%, P = 0·002] compared with donors without HS. Furthermore, significantly more donors with HS were classified as having moderate depression (3·2% vs. 0·7%, P < 0·001). Also, significantly more patients with HS were apprenticeship educated, received educational support and sickness or cash benefits. Conclusions: The prevalence of HS in the cohort of blood donors was estimated to 1·8% (95% CI 1·6–2·0%). Donors with HS reported characteristics similar to those reported for hospital-based patients with HS such as higher BMI, smoking rates and lower socioeconomic status than donors without HS.

OriginalsprogEngelsk
TidsskriftBritish Journal of Dermatology
Vol/bind180
Udgave nummer4
Sider (fra-til)774-781
ISSN0007-0963
DOI
StatusUdgivet - apr. 2019

Fingeraftryk

Hidradenitis Suppurativa
Cross-Sectional Studies
Body Mass Index
Confidence Intervals
Depression
Skin Diseases
Smoke

Citer dette

Theut Riis, P. ; Pedersen, O. B. ; Sigsgaard, V. ; Erikstrup, C. ; Paarup, H. M. ; Nielsen, K. R. ; Burgdorf, K. S. ; Hjalgrim, H. ; Rostgaard, K. ; Banasik, K. ; Ullum, H. ; Jemec, G. B. / Prevalence of patients with self-reported hidradenitis suppurativa in a cohort of Danish blood donors : a cross-sectional study. I: British Journal of Dermatology. 2019 ; Bind 180, Nr. 4. s. 774-781.
@article{91c6fa19e10b4b09b95ad3ea2680f5c0,
title = "Prevalence of patients with self-reported hidradenitis suppurativa in a cohort of Danish blood donors: a cross-sectional study",
abstract = "Background: Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease characterized by recurrent inflamed nodules. No pathognomonic test is available for HS; hence the diagnosis is based on three clinical criteria. Objectives: To estimate the cross-sectional prevalence and characterize patients with HS in the Danish Blood Donor Study cohort. Methods: A questionnaire previously developed containing HS screening questions, the Major Depression Inventory, the Short Form-12, as well as questions about height, weight and drinking habits was answered by 27 765 blood donors. Results: The prevalence of HS was 1·8{\%} [95{\%} confidence interval (CI) 1·6–2·0{\%}] in the cohort of Danish blood donors. Donors with HS were on average 4·7 years younger (P < 0·001), had 1·3 kg m−2 higher mean body mass index (BMI) (P < 0·001) and were significantly more likely to smoke [odds ratio (OR) 1·44, 17·9{\%} vs. 13·1{\%}, P = 0·002] compared with donors without HS. Furthermore, significantly more donors with HS were classified as having moderate depression (3·2{\%} vs. 0·7{\%}, P < 0·001). Also, significantly more patients with HS were apprenticeship educated, received educational support and sickness or cash benefits. Conclusions: The prevalence of HS in the cohort of blood donors was estimated to 1·8{\%} (95{\%} CI 1·6–2·0{\%}). Donors with HS reported characteristics similar to those reported for hospital-based patients with HS such as higher BMI, smoking rates and lower socioeconomic status than donors without HS.",
author = "{Theut Riis}, P. and Pedersen, {O. B.} and V. Sigsgaard and C. Erikstrup and Paarup, {H. M.} and Nielsen, {K. R.} and Burgdorf, {K. S.} and H. Hjalgrim and K. Rostgaard and K. Banasik and H. Ullum and Jemec, {G. B.}",
year = "2019",
month = "4",
doi = "10.1111/bjd.16998",
language = "English",
volume = "180",
pages = "774--781",
journal = "British Journal of Dermatology",
issn = "0007-0963",
publisher = "Wiley-Blackwell",
number = "4",

}

Theut Riis, P, Pedersen, OB, Sigsgaard, V, Erikstrup, C, Paarup, HM, Nielsen, KR, Burgdorf, KS, Hjalgrim, H, Rostgaard, K, Banasik, K, Ullum, H & Jemec, GB 2019, 'Prevalence of patients with self-reported hidradenitis suppurativa in a cohort of Danish blood donors: a cross-sectional study', British Journal of Dermatology, bind 180, nr. 4, s. 774-781. https://doi.org/10.1111/bjd.16998

Prevalence of patients with self-reported hidradenitis suppurativa in a cohort of Danish blood donors : a cross-sectional study. / Theut Riis, P.; Pedersen, O. B.; Sigsgaard, V.; Erikstrup, C.; Paarup, H. M.; Nielsen, K. R.; Burgdorf, K. S.; Hjalgrim, H.; Rostgaard, K.; Banasik, K.; Ullum, H.; Jemec, G. B.

I: British Journal of Dermatology, Bind 180, Nr. 4, 04.2019, s. 774-781.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

TY - JOUR

T1 - Prevalence of patients with self-reported hidradenitis suppurativa in a cohort of Danish blood donors

T2 - a cross-sectional study

AU - Theut Riis, P.

AU - Pedersen, O. B.

AU - Sigsgaard, V.

AU - Erikstrup, C.

AU - Paarup, H. M.

AU - Nielsen, K. R.

AU - Burgdorf, K. S.

AU - Hjalgrim, H.

AU - Rostgaard, K.

AU - Banasik, K.

AU - Ullum, H.

AU - Jemec, G. B.

PY - 2019/4

Y1 - 2019/4

N2 - Background: Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease characterized by recurrent inflamed nodules. No pathognomonic test is available for HS; hence the diagnosis is based on three clinical criteria. Objectives: To estimate the cross-sectional prevalence and characterize patients with HS in the Danish Blood Donor Study cohort. Methods: A questionnaire previously developed containing HS screening questions, the Major Depression Inventory, the Short Form-12, as well as questions about height, weight and drinking habits was answered by 27 765 blood donors. Results: The prevalence of HS was 1·8% [95% confidence interval (CI) 1·6–2·0%] in the cohort of Danish blood donors. Donors with HS were on average 4·7 years younger (P < 0·001), had 1·3 kg m−2 higher mean body mass index (BMI) (P < 0·001) and were significantly more likely to smoke [odds ratio (OR) 1·44, 17·9% vs. 13·1%, P = 0·002] compared with donors without HS. Furthermore, significantly more donors with HS were classified as having moderate depression (3·2% vs. 0·7%, P < 0·001). Also, significantly more patients with HS were apprenticeship educated, received educational support and sickness or cash benefits. Conclusions: The prevalence of HS in the cohort of blood donors was estimated to 1·8% (95% CI 1·6–2·0%). Donors with HS reported characteristics similar to those reported for hospital-based patients with HS such as higher BMI, smoking rates and lower socioeconomic status than donors without HS.

AB - Background: Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease characterized by recurrent inflamed nodules. No pathognomonic test is available for HS; hence the diagnosis is based on three clinical criteria. Objectives: To estimate the cross-sectional prevalence and characterize patients with HS in the Danish Blood Donor Study cohort. Methods: A questionnaire previously developed containing HS screening questions, the Major Depression Inventory, the Short Form-12, as well as questions about height, weight and drinking habits was answered by 27 765 blood donors. Results: The prevalence of HS was 1·8% [95% confidence interval (CI) 1·6–2·0%] in the cohort of Danish blood donors. Donors with HS were on average 4·7 years younger (P < 0·001), had 1·3 kg m−2 higher mean body mass index (BMI) (P < 0·001) and were significantly more likely to smoke [odds ratio (OR) 1·44, 17·9% vs. 13·1%, P = 0·002] compared with donors without HS. Furthermore, significantly more donors with HS were classified as having moderate depression (3·2% vs. 0·7%, P < 0·001). Also, significantly more patients with HS were apprenticeship educated, received educational support and sickness or cash benefits. Conclusions: The prevalence of HS in the cohort of blood donors was estimated to 1·8% (95% CI 1·6–2·0%). Donors with HS reported characteristics similar to those reported for hospital-based patients with HS such as higher BMI, smoking rates and lower socioeconomic status than donors without HS.

U2 - 10.1111/bjd.16998

DO - 10.1111/bjd.16998

M3 - Journal article

VL - 180

SP - 774

EP - 781

JO - British Journal of Dermatology

JF - British Journal of Dermatology

SN - 0007-0963

IS - 4

ER -